1H7KA

Formation of a tyrosyl radical intermediate in proteus mirabilis catalase by directed mutagenesis and consequences for nucleotide reactivity
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
475
structure length
474
Chain Sequence
KKLTTAAGAPVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYKWDFFSHLPESLHQLTIDMSDRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHYRCQQGIKNLMDDEAEALVGKDRESSQRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELNRNPDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPKCPFHNYHRDGAMRVDGNSGNGITYEPNSGGVFQEQPDFKEPPLSIEGAADHWNHREDEDYFSQPRALYELLSDDEHQRMFARIAGELSQASKETQQRQIDLFTKVHPEYGAGVEKAIKVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Formation of a Tyrosyl Radical Intermediate in Proteus Mirabilis Catalase by Directed Mutagenesis and Consequences for Nucleotide Reactivity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Proteus mirabilis
molecule keywords CATALASE
total genus 142
structure length 474
sequence length 475
ec nomenclature ec 1.11.1.6: Catalase.
pdb deposition date 2001-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00199 Catalase Catalase
A PF06628 Catalase-rel Catalase-related immune-responsive
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.180.10 Mainly Beta Beta Barrel Catalase HpII, Chain A, domain 1 Catalase core domain 1h7kA00
1A4EA 1GGKA 1GGFA 1IPHA 1M7SA 1GGEA 3EJ6A 3PQ4A 3PQ5A 1P7YA 1GWHA 2XF2A 4QOMA 1GGJA 1QWSA 3P9QA 1SI8A 4AJ9A 1QWLA 4B2YA 3PQ8A 4BIMA 3P9SA 3PQ7A 1P80A 4ENUA 1E93A 3TTTA 4QOQA 1CF9A 1MQFA 4E37A 4ENPA 4ENVA 4ENTA 3PQ3A 3PQ2A 4QOLA 2XQ1A 2ISAA 4ENWA 4AULA 3TTVA 1QWMA 3P9RA 2J2MA 2IQFA 4B40A 2IUFA 1F4JA 5BV2P 1SY7A 3PQ6A 1HBZA 4QORA 2CAGA 1P7ZA 4ENQA 4CABA 1GGHA 1GWFA 4BFLA 4AUNA 1M85A 1QF7A 3TTUA 1GWEA 4B5KA 1H7KA 3TTWA 3VU3A 4QOPA 3ZJ5A 4B7AA 3DY5A 3ZJ4A 1H6NA 2A9EA 2CAHA 4AUEA 4B31A 3HB6A 1U5UA 1GG9A 4AUMA 4QOOA 4QONA 3P9PA 3TTXA 4ENSA 1P81A 1NM0A 4ENRA
chains in the Genus database with same CATH superfamily
1A4EA 1GGKA 1GGFA 1TH4A 1IPHA 1M7SA 1GGEA 3EJ6A 3PQ4A 1TGUA 3PQ5A 1P7YA 1GWHA 1DGFA 2XF2A 4QOMA 1GGJA 1QWSA 3P9QA 1SI8A 4AJ9A 1QWLA 1QQWA 4B2YA 3PQ8A 4BIMA 3P9SA 3PQ7A 1P80A 4ENUA 3E4WA 1E93A 3TTTA 4BLCA 4QOQA 1CF9A 1MQFA 4E37A 3RE8A 4ENPA 4ENVA 4ENTA 3PQ3A 3PQ2A 4QOLA 2XQ1A 2ISAA 4ENWA 4AULA 1TH3A 3TTVA 1QWMA 3P9RA 2J2MA 2IQFA 4B40A 2IUFA 1F4JA 5BV2P 1DGHA 1SY7A 3NWLA 3PQ6A 1HBZA 4QORA 2CAGA 1P7ZA 4ENQA 4CABA 1DGGA 1GGHA 4B7FA 1GWFA 3RGPA 4BFLA 1DGBA 4AUNA 1M85A 1QF7A 3TTUA 1GWEA 4B5KA 1H7KA 4ENRA 5GKNA 3RGSA 3TTWA 3VU3A 4QOPA 3ZJ5A 4B7AA 3E4YA 3DY5A 3ZJ4A 1H6NA 2A9EA 2CAHA 4B7HA 4AUEA 4B31A 3HB6A 1TH2A 1U5UA 1GG9A 8CATA 1DGHB 4AUMA 4QOOA 4QONA 3P9PA 7CATA 3TTXA 4ENSA 1P81A 4B7GA 1NM0A 3J7BA
chains in the Genus database with same CATH topology
1A4EA 1GGKA 1GGFA 1IPHA 1M7SA 1GGEA 3EJ6A 3PQ4A 3PQ5A 1P7YA 1GWHA 2XF2A 4QOMA 1GGJA 1QWSA 3P9QA 1SI8A 4AJ9A 1QWLA 4B2YA 3PQ8A 4BIMA 3P9SA 3PQ7A 1P80A 4ENUA 1E93A 3TTTA 4QOQA 1CF9A 1MQFA 4E37A 4ENPA 4ENVA 4ENTA 3PQ3A 3PQ2A 4QOLA 2XQ1A 2ISAA 4ENWA 4AULA 3TTVA 1QWMA 3P9RA 2J2MA 2IQFA 4B40A 2IUFA 1F4JA 5BV2P 1SY7A 3PQ6A 1HBZA 4QORA 2CAGA 1P7ZA 4ENQA 4CABA 1GGHA 1GWFA 4BFLA 4AUNA 1M85A 1QF7A 3TTUA 1GWEA 4B5KA 1H7KA 3TTWA 3VU3A 4QOPA 3ZJ5A 4B7AA 3DY5A 3ZJ4A 1H6NA 2A9EA 2CAHA 4AUEA 4B31A 3HB6A 1U5UA 1GG9A 4AUMA 4QOOA 4QONA 3P9PA 3TTXA 4ENSA 1P81A 1NM0A 4ENRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A4E A;  1GGK A;  1GGF A;  1IPH A;  1M7S A;  1GGE A;  3EJ6 A;  3PQ4 A;  3PQ5 A;  1P7Y A;  1GWH A;  2XF2 A;  4QOM A;  1GGJ A;  1QWS A;  3P9Q A;  1SI8 A;  4AJ9 A;  1QWL A;  4B2Y A;  3PQ8 A;  4BIM A;  3P9S A;  3PQ7 A;  1P80 A;  4ENU A;  1E93 A;  3TTT A;  4QOQ A;  1CF9 A;  1MQF A;  4E37 A;  4ENP A;  4ENV A;  4ENT A;  3PQ3 A;  3PQ2 A;  4QOL A;  2XQ1 A;  2ISA A;  4ENW A;  4AUL A;  3TTV A;  1QWM A;  3P9R A;  2J2M A;  2IQF A;  4B40 A;  2IUF A;  1F4J A;  5BV2 P;  1SY7 A;  3PQ6 A;  1HBZ A;  4QOR A;  2CAG A;  1P7Z A;  4ENQ A;  4CAB A;  1GGH A;  1GWF A;  4BFL A;  4AUN A;  1M85 A;  1QF7 A;  3TTU A;  1GWE A;  4B5K A;  1H7K A;  3TTW A;  3VU3 A;  4QOP A;  3ZJ5 A;  4B7A A;  3DY5 A;  3ZJ4 A;  1H6N A;  2A9E A;  2CAH A;  4AUE A;  4B31 A;  3HB6 A;  1U5U A;  1GG9 A;  4AUM A;  4QOO A;  4QON A;  3P9P A;  3TTX A;  4ENS A;  1P81 A;  1NM0 A;  4ENR A; 
#chains in the Genus database with same CATH topology
 1A4E A;  1GGK A;  1GGF A;  1TH4 A;  1IPH A;  1M7S A;  1GGE A;  3EJ6 A;  3PQ4 A;  1TGU A;  3PQ5 A;  1P7Y A;  1GWH A;  1DGF A;  2XF2 A;  4QOM A;  1GGJ A;  1QWS A;  3P9Q A;  1SI8 A;  4AJ9 A;  1QWL A;  1QQW A;  4B2Y A;  3PQ8 A;  4BIM A;  3P9S A;  3PQ7 A;  1P80 A;  4ENU A;  3E4W A;  1E93 A;  3TTT A;  4BLC A;  4QOQ A;  1CF9 A;  1MQF A;  4E37 A;  3RE8 A;  4ENP A;  4ENV A;  4ENT A;  3PQ3 A;  3PQ2 A;  4QOL A;  2XQ1 A;  2ISA A;  4ENW A;  4AUL A;  1TH3 A;  3TTV A;  1QWM A;  3P9R A;  2J2M A;  2IQF A;  4B40 A;  2IUF A;  1F4J A;  5BV2 P;  1DGH A;  1SY7 A;  3NWL A;  3PQ6 A;  1HBZ A;  4QOR A;  2CAG A;  1P7Z A;  4ENQ A;  4CAB A;  1DGG A;  1GGH A;  4B7F A;  1GWF A;  3RGP A;  4BFL A;  1DGB A;  4AUN A;  1M85 A;  1QF7 A;  3TTU A;  1GWE A;  4B5K A;  1H7K A;  4ENR A;  5GKN A;  3RGS A;  3TTW A;  3VU3 A;  4QOP A;  3ZJ5 A;  4B7A A;  3E4Y A;  3DY5 A;  3ZJ4 A;  1H6N A;  2A9E A;  2CAH A;  4B7H A;  4AUE A;  4B31 A;  3HB6 A;  1TH2 A;  1U5U A;  1GG9 A;  8CAT A;  1DGH B;  4AUM A;  4QOO A;  4QON A;  3P9P A;  7CAT A;  3TTX A;  4ENS A;  1P81 A;  4B7G A;  1NM0 A;  3J7B A; 
#chains in the Genus database with same CATH homology
 1A4E A;  1GGK A;  1GGF A;  1IPH A;  1M7S A;  1GGE A;  3EJ6 A;  3PQ4 A;  3PQ5 A;  1P7Y A;  1GWH A;  2XF2 A;  4QOM A;  1GGJ A;  1QWS A;  3P9Q A;  1SI8 A;  4AJ9 A;  1QWL A;  4B2Y A;  3PQ8 A;  4BIM A;  3P9S A;  3PQ7 A;  1P80 A;  4ENU A;  1E93 A;  3TTT A;  4QOQ A;  1CF9 A;  1MQF A;  4E37 A;  4ENP A;  4ENV A;  4ENT A;  3PQ3 A;  3PQ2 A;  4QOL A;  2XQ1 A;  2ISA A;  4ENW A;  4AUL A;  3TTV A;  1QWM A;  3P9R A;  2J2M A;  2IQF A;  4B40 A;  2IUF A;  1F4J A;  5BV2 P;  1SY7 A;  3PQ6 A;  1HBZ A;  4QOR A;  2CAG A;  1P7Z A;  4ENQ A;  4CAB A;  1GGH A;  1GWF A;  4BFL A;  4AUN A;  1M85 A;  1QF7 A;  3TTU A;  1GWE A;  4B5K A;  1H7K A;  3TTW A;  3VU3 A;  4QOP A;  3ZJ5 A;  4B7A A;  3DY5 A;  3ZJ4 A;  1H6N A;  2A9E A;  2CAH A;  4AUE A;  4B31 A;  3HB6 A;  1U5U A;  1GG9 A;  4AUM A;  4QOO A;  4QON A;  3P9P A;  3TTX A;  4ENS A;  1P81 A;  1NM0 A;  4ENR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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