2BOWA

Multidrug-binding domain of transcription activator bmrr in complex with a ligand, tetraphenylphosphonium
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
157
structure length
130
Chain Sequence
LGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSYGATFSFQPYTSIDEMTYRHIFTPVLTISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYRVEMKIRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
pubmed doi rcsb
molecule keywords MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR
molecule tags Transcription activator
source organism Bacillus subtilis
total genus 25
structure length 130
sequence length 157
ec nomenclature
pdb deposition date 1998-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 2bowA00
3D6ZA 1JYHA 3B49A 2HVAA 4AYZB 1D5YA 1R8EA 5KAWA 3GK6A 2BOWA 3Q2YA 3Q3DA 2KCUA 3Q1MA 1EXIA 4AYZA 5KCBA 3Q5SA 3E0HA 3Q5RA 3D6YA 4A1MA 2GOVA 5KATA 1EXJA 3IAOA 3D71A 3R8KA 5KAXA 5KAUA 4B0YA 3R8JA 3D70A 3LURA 5KAVA 1BOWA 3Q5PA 5GQQA
chains in the Genus database with same CATH superfamily
3D6ZA 1JYHA 3B49A 2HVAA 4AYZB 1D5YA 1R8EA 5KAWA 3GK6A 2BOWA 3Q2YA 3Q3DA 2KCUA 3Q1MA 1EXIA 4AYZA 5KCBA 3Q5SA 3E0HA 3Q5RA 3D6YA 4A1MA 2GOVA 5KATA 1EXJA 3IAOA 3D71A 3R8KA 5KAXA 5KAUA 4B0YA 3R8JA 3D70A 3LURA 5KAVA 1BOWA 3Q5PA 5GQQA
chains in the Genus database with same CATH topology
3D6ZA 1JYHA 3B49A 2HVAA 4AYZB 1D5YA 1R8EA 5KAWA 3GK6A 2BOWA 3Q2YA 3Q3DA 2KCUA 3Q1MA 1EXIA 4AYZA 5KCBA 3Q5SA 3E0HA 3Q5RA 3D6YA 4A1MA 2GOVA 5KATA 1EXJA 3IAOA 3D71A 3R8KA 5KAXA 5KAUA 4B0YA 3R8JA 3D70A 3LURA 5KAVA 1BOWA 3Q5PA 5GQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D6Z A;  1JYH A;  3B49 A;  2HVA A;  4AYZ B;  1D5Y A;  1R8E A;  5KAW A;  3GK6 A;  2BOW A;  3Q2Y A;  3Q3D A;  2KCU A;  3Q1M A;  1EXI A;  4AYZ A;  5KCB A;  3Q5S A;  3E0H A;  3Q5R A;  3D6Y A;  4A1M A;  2GOV A;  5KAT A;  1EXJ A;  3IAO A;  3D71 A;  3R8K A;  5KAX A;  5KAU A;  4B0Y A;  3R8J A;  3D70 A;  3LUR A;  5KAV A;  1BOW A;  3Q5P A;  5GQQ A; 
#chains in the Genus database with same CATH topology
 3D6Z A;  1JYH A;  3B49 A;  2HVA A;  4AYZ B;  1D5Y A;  1R8E A;  5KAW A;  3GK6 A;  2BOW A;  3Q2Y A;  3Q3D A;  2KCU A;  3Q1M A;  1EXI A;  4AYZ A;  5KCB A;  3Q5S A;  3E0H A;  3Q5R A;  3D6Y A;  4A1M A;  2GOV A;  5KAT A;  1EXJ A;  3IAO A;  3D71 A;  3R8K A;  5KAX A;  5KAU A;  4B0Y A;  3R8J A;  3D70 A;  3LUR A;  5KAV A;  1BOW A;  3Q5P A;  5GQQ A; 
#chains in the Genus database with same CATH homology
 3D6Z A;  1JYH A;  3B49 A;  2HVA A;  4AYZ B;  1D5Y A;  1R8E A;  5KAW A;  3GK6 A;  2BOW A;  3Q2Y A;  3Q3D A;  2KCU A;  3Q1M A;  1EXI A;  4AYZ A;  5KCB A;  3Q5S A;  3E0H A;  3Q5R A;  3D6Y A;  4A1M A;  2GOV A;  5KAT A;  1EXJ A;  3IAO A;  3D71 A;  3R8K A;  5KAX A;  5KAU A;  4B0Y A;  3R8J A;  3D70 A;  3LUR A;  5KAV A;  1BOW A;  3Q5P A;  5GQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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