2BOWA

Multidrug-binding domain of transcription activator bmrr in complex with a ligand, tetraphenylphosphonium
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
157
structure length
130
Chain Sequence
LGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSYGATFSFQPYTSIDEMTYRHIFTPVLTISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYRVEMKIRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
pubmed doi rcsb
molecule tags Transcription activator
source organism Bacillus subtilis
molecule keywords MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR
total genus 25
structure length 130
sequence length 157
ec nomenclature
pdb deposition date 1998-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 2bowA00
3Q3DA 5KATA 3Q1MA 3IAOA 3Q2YA 2KCUA 4AYZA 1EXJA 3D70A 5GQQA 2GOVA 3D71A 1BOWA 3GK6A 3D6YA 1JYHA 5KAWA 5KAXA 3D6ZA 3Q5PA 5KAUA 5KCBA 3E0HA 2BOWA 5KAVA 2HVAA 3Q5RA 4B0YA 1EXIA 3R8KA 3R8JA 4A1MA 3B49A 1R8EA 4AYZB 3Q5SA 1D5YA 3LURA
chains in the Genus database with same CATH superfamily
3Q3DA 5KATA 3Q1MA 3IAOA 3Q2YA 2KCUA 4AYZA 1EXJA 3D70A 5GQQA 2GOVA 3D71A 1BOWA 3GK6A 3D6YA 1JYHA 5KAWA 5KAXA 3D6ZA 3Q5PA 5KAUA 5KCBA 3E0HA 2BOWA 5KAVA 2HVAA 3Q5RA 4B0YA 1EXIA 3R8KA 3R8JA 4A1MA 3B49A 1R8EA 4AYZB 3Q5SA 1D5YA 3LURA
chains in the Genus database with same CATH topology
3Q3DA 5KATA 3Q1MA 3IAOA 3Q2YA 2KCUA 4AYZA 1EXJA 3D70A 5GQQA 2GOVA 3D71A 1BOWA 3GK6A 3D6YA 1JYHA 5KAWA 5KAXA 3D6ZA 3Q5PA 5KAUA 5KCBA 3E0HA 2BOWA 5KAVA 2HVAA 3Q5RA 4B0YA 1EXIA 3R8KA 3R8JA 4A1MA 3B49A 1R8EA 4AYZB 3Q5SA 1D5YA 3LURA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q3D A;  5KAT A;  3Q1M A;  3IAO A;  3Q2Y A;  2KCU A;  4AYZ A;  1EXJ A;  3D70 A;  5GQQ A;  2GOV A;  3D71 A;  1BOW A;  3GK6 A;  3D6Y A;  1JYH A;  5KAW A;  5KAX A;  3D6Z A;  3Q5P A;  5KAU A;  5KCB A;  3E0H A;  2BOW A;  5KAV A;  2HVA A;  3Q5R A;  4B0Y A;  1EXI A;  3R8K A;  3R8J A;  4A1M A;  3B49 A;  1R8E A;  4AYZ B;  3Q5S A;  1D5Y A;  3LUR A; 
#chains in the Genus database with same CATH topology
 3Q3D A;  5KAT A;  3Q1M A;  3IAO A;  3Q2Y A;  2KCU A;  4AYZ A;  1EXJ A;  3D70 A;  5GQQ A;  2GOV A;  3D71 A;  1BOW A;  3GK6 A;  3D6Y A;  1JYH A;  5KAW A;  5KAX A;  3D6Z A;  3Q5P A;  5KAU A;  5KCB A;  3E0H A;  2BOW A;  5KAV A;  2HVA A;  3Q5R A;  4B0Y A;  1EXI A;  3R8K A;  3R8J A;  4A1M A;  3B49 A;  1R8E A;  4AYZ B;  3Q5S A;  1D5Y A;  3LUR A; 
#chains in the Genus database with same CATH homology
 3Q3D A;  5KAT A;  3Q1M A;  3IAO A;  3Q2Y A;  2KCU A;  4AYZ A;  1EXJ A;  3D70 A;  5GQQ A;  2GOV A;  3D71 A;  1BOW A;  3GK6 A;  3D6Y A;  1JYH A;  5KAW A;  5KAX A;  3D6Z A;  3Q5P A;  5KAU A;  5KCB A;  3E0H A;  2BOW A;  5KAV A;  2HVA A;  3Q5R A;  4B0Y A;  1EXI A;  3R8K A;  3R8J A;  4A1M A;  3B49 A;  1R8E A;  4AYZ B;  3Q5S A;  1D5Y A;  3LUR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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