2IO7A

E. coli bifunctional glutathionylspermidine synthetase/amidase incomplex with mg2+ and amppnp
Total Genus 160
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
160
sequence length
606
structure length
587
Chain Sequence
APFGTLLGYAPGGVAIYSSDYRSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEENYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQIREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFPHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNIYQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
pubmed doi rcsb
molecule tags Ligase, hydrolase
source organism Escherichia coli
molecule keywords Bifunctional glutathionylspermidine synthetase/amidase
total genus 160
structure length 587
sequence length 606
chains with identical sequence B
ec nomenclature ec 3.5.1.78: Glutathionylspermidine amidase.
pdb deposition date 2006-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03738 GSP_synth Glutathionylspermidine synthase preATP-grasp
A PF05257 CHAP CHAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1720.10 Alpha Beta Alpha-Beta Complex endopeptidase fold (from Nostoc punctiforme) endopeptidase domain like (from Nostoc punctiforme) 2io7A01
2IOAA 4FGDA 3I86A 4F0VA 4EOBA 2IOBA 3GT2A 3PVQA 3H41A 4HZ9A 3A30A 4FGIA 4OLKA 4HPEA 4EQ8A 3A2ZA 3S0QA 4CT3A 3KW0A 2HBWA 2XIVA 3A2YA 3NPFA 2LRJA 3PBCA 4FQBA 2VOBA 2EVRA 4F0WA 4F4MA 4FQAA 4JXBA 4EQAA 3PBIA 2K1GA 4Q4TA 2VPMA 2FG0A 2IO7A 3NE0A 4FDYA 4FGEA 4R0KA 4CSHA 2IO8A 4Q4NA 3M1UA 2VPSA 3O98A 2IO9A 4Q4GX 3VPIA 2K3AA 4LJ1A 4CGKA 4HZBA 3VPJA 2IF6A
chains in the Genus database with same CATH superfamily
2IOAA 4FGDA 3I86A 4J30A 4F0VA 4EOBA 2IOBA 4J32A 3GT2A 3PVQA 3H41A 4HZ9A 3A30A 4FGIA 4OLKA 4HPEA 4EQ8A 3A2ZA 4HFKA 3S0QA 4CT3A 3KW0A 2HBWA 2XIVA 3A2YA 3NPFA 2LRJA 3PBCA 4FQBA 2VOBA 2EVRA 4F0WA 4F4MA 4HFFA 4FQAA 4JXBA 4EQAA 3EBQA 4JURA 2WP7A 3PBIA 2K1GA 4Q4TA 2VPMA 2FG0A 2IO7A 3NE0A 4FDYA 4FGEA 4R0KA 4CSHA 2IO8A 4Q4NA 3M1UA 2VPSA 4HFLA 3O98A 2IO9A 4Q4GX 3VPIA 2K3AA 4LJ1A 4CGKA 4HZBA 3VPJA 2IF6A
chains in the Genus database with same CATH topology
2IOAA 4FGDA 3I86A 4F0VA 4EOBA 2IOBA 3GT2A 3PVQA 3H41A 4HZ9A 3A30A 4FGIA 4OLKA 4HPEA 4EQ8A 3A2ZA 3S0QA 4CT3A 3KW0A 2HBWA 2XIVA 3A2YA 3NPFA 2LRJA 3PBCA 4FQBA 2VOBA 2EVRA 4F0WA 4F4MA 4FQAA 4JXBA 4EQAA 3PBIA 2K1GA 4Q4TA 2VPMA 2FG0A 2IO7A 3NE0A 4FDYA 4FGEA 4R0KA 4CSHA 2IO8A 4Q4NA 3M1UA 2VPSA 3O98A 2IO9A 4Q4GX 3VPIA 2K3AA 4LJ1A 4CGKA 4HZBA 3VPJA 2IF6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IOA A;  4FGD A;  3I86 A;  4F0V A;  4EOB A;  2IOB A;  3GT2 A;  3PVQ A;  3H41 A;  4HZ9 A;  3A30 A;  4FGI A;  4OLK A;  4HPE A;  4EQ8 A;  3A2Z A;  3S0Q A;  4CT3 A;  3KW0 A;  2HBW A;  2XIV A;  3A2Y A;  3NPF A;  2LRJ A;  3PBC A;  4FQB A;  2VOB A;  2EVR A;  4F0W A;  4F4M A;  4FQA A;  4JXB A;  4EQA A;  3PBI A;  2K1G A;  4Q4T A;  2VPM A;  2FG0 A;  2IO7 A;  3NE0 A;  4FDY A;  4FGE A;  4R0K A;  4CSH A;  2IO8 A;  4Q4N A;  3M1U A;  2VPS A;  3O98 A;  2IO9 A;  4Q4G X;  3VPI A;  2K3A A;  4LJ1 A;  4CGK A;  4HZB A;  3VPJ A;  2IF6 A; 
#chains in the Genus database with same CATH topology
 2IOA A;  4FGD A;  3I86 A;  4J30 A;  4F0V A;  4EOB A;  2IOB A;  4J32 A;  3GT2 A;  3PVQ A;  3H41 A;  4HZ9 A;  3A30 A;  4FGI A;  4OLK A;  4HPE A;  4EQ8 A;  3A2Z A;  4HFK A;  3S0Q A;  4CT3 A;  3KW0 A;  2HBW A;  2XIV A;  3A2Y A;  3NPF A;  2LRJ A;  3PBC A;  4FQB A;  2VOB A;  2EVR A;  4F0W A;  4F4M A;  4HFF A;  4FQA A;  4JXB A;  4EQA A;  3EBQ A;  4JUR A;  2WP7 A;  3PBI A;  2K1G A;  4Q4T A;  2VPM A;  2FG0 A;  2IO7 A;  3NE0 A;  4FDY A;  4FGE A;  4R0K A;  4CSH A;  2IO8 A;  4Q4N A;  3M1U A;  2VPS A;  4HFL A;  3O98 A;  2IO9 A;  4Q4G X;  3VPI A;  2K3A A;  4LJ1 A;  4CGK A;  4HZB A;  3VPJ A;  2IF6 A; 
#chains in the Genus database with same CATH homology
 2IOA A;  4FGD A;  3I86 A;  4F0V A;  4EOB A;  2IOB A;  3GT2 A;  3PVQ A;  3H41 A;  4HZ9 A;  3A30 A;  4FGI A;  4OLK A;  4HPE A;  4EQ8 A;  3A2Z A;  3S0Q A;  4CT3 A;  3KW0 A;  2HBW A;  2XIV A;  3A2Y A;  3NPF A;  2LRJ A;  3PBC A;  4FQB A;  2VOB A;  2EVR A;  4F0W A;  4F4M A;  4FQA A;  4JXB A;  4EQA A;  3PBI A;  2K1G A;  4Q4T A;  2VPM A;  2FG0 A;  2IO7 A;  3NE0 A;  4FDY A;  4FGE A;  4R0K A;  4CSH A;  2IO8 A;  4Q4N A;  3M1U A;  2VPS A;  3O98 A;  2IO9 A;  4Q4G X;  3VPI A;  2K3A A;  4LJ1 A;  4CGK A;  4HZB A;  3VPJ A;  2IF6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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