2VPSA

Structure of the bifunctional leishmania major trypanothione synthetase-amidase
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
651
structure length
603
Chain Sequence
SSLQRASVSFNKPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGERNIEDNIFFGFKYQCVEFARRWLLVRKGLLLPDVNWACHIFQLKEVRDAATTESFAVLQVRNGTTTKPEADALLVYPSTDANPVGHVGTITEVGDDYVCVADQNYRFHKWESSCAYKLKLDHRDGIWTIIDDIDADEIEIPLGWLTFPGRANRPEGAPPVALHPSLHFKEPPKPYLLRRNFLPTESKANWLDMNNPAERLFVEEFGVVSYYESNHEFHLRCVAYGTQLHAIFMEATAQVIESDEKLRLFAIPEEFWPRIRHSWKYQQTYISGRFDFAFNNETGEVKCFEYNADSASTLLECGLIQQKWAESVGLDKQDTRGSGFAVERNLKMAWANSGATGRVHFCVDEEREEQYTALYCMQAAEAVGLEGKLCILFDEFRFDDNGHVVDSDGVRVRNVWKTWMWESAITDYYAAREERGENWKPSPKDKVRLCDLLLGDDWEILYFEPMWKVIPSNKAILPMIYHNHPEHPAILKAEYELTDELRKHGYAKKPIVNMIYQQLFELKKQDDYYAIIGGWMIGDAFSGTGIREDKSVITGVDSPFAAVRIKTDIDKMAEDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Leishmania Trypanothione Synthetase-Amidase Structure Reveals a Basis for Regulation of Conflicting Synthetic and Hydrolytic Activities.
pubmed doi rcsb
source organism Leishmania major
molecule tags Ligase
molecule keywords TRYPANOTHIONE SYNTHETASE
total genus 175
structure length 603
sequence length 651
ec nomenclature ec 6.3.1.9: Trypanothione synthase.
pdb deposition date 2008-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03738 GSP_synth Glutathionylspermidine synthase preATP-grasp
A PF05257 CHAP CHAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1490.330 Alpha Beta 2-Layer Sandwich Dna Ligase; domain 1 Dna Ligase; domain 1 2vpsA03
3.90.1720.10 Alpha Beta Alpha-Beta Complex endopeptidase fold (from Nostoc punctiforme) endopeptidase domain like (from Nostoc punctiforme) 2vpsA02
3NE0A 3O98A 4HZ9A 3VPJA 4FGDA 4FGEA 3PBIA 2IO8A 4EQ8A 3S0QA 2IO7A 4FQAA 2EVRA 2K3AA 3I86A 3A2ZA 2IO9A 2LRJA 2VOBA 2IOBA 3H41A 4Q4TA 4OLKA 4R0KA 4JXBA 4FDYA 4EQAA 3A2YA 2K1GA 3VPIA 4Q4NA 3M1UA 3NPFA 4CGKA 2VPMA 4CSHA 4FQBA 4EOBA 4HPEA 2HBWA 2VPSA 2FG0A 2IOAA 3PVQA 4HZBA 2IF6A 4FGIA 4LJ1A 4CT3A 3A30A 4F0WA 4F0VA 3KW0A 2XIVA 4F4MA 3PBCA 4Q4GX 3GT2A
chains in the Genus database with same CATH superfamily
3ORQA 2P0AA 1W96A 3HOYG 3PBIA 2IO8A 1B6RA 3Q8RB 1IBMH 4LMYA 3PW7A 3JZIA 1WCMA 3JRWA 5LA6F 1KEEA 2UXBH 5KFTA 1S68A 4YR2A 3CQZA 1M0WA 5BPHA 1AUVA 4DV0H 5CA1F 4ED8A 3HOXG 1ZHQA 4JXBA 3EYYA 2UVUA 3VMMA 4J9SA 3FKIG 4QWDA 4EOBA 5FD5A 3OSNA 3JSLA 5KT5A 2HHHH 3GTOA 5BR8H 2VQFH 2W9BB 5FLXW 2NUAB 4Q44A 2OLSA 4FGIA 3GQCA 4Q8FA 1WCMG 3GTGA 4F50A 1TWFA 4RB2C 4ECTA 1S10A 4XZ3B 3GV7B 3PW0A 3H4BA 1OWTA 2FMAA 4RNOA 3OTOH 2WB1A 3GV8B 3RUPA 4ED2A 3BA8A 3JAMW 2W9BA 2PBZA 4DUZH 4MAMA 4JI0H 2AGPA 3KAJA 4J0MA 4QIWA 2I87A 2XC9A 4ECYA 3QZ8A 4ECRA 3HKZE 1N36H 3V4SA 5KFMA 3N41B 1M0TA 4FS1A 2R7MA 4QWAA 5EWGA 5KFHA 4Q4NA 2YL2A 4RB1A 4C5BA 2YW2A 2O03A 3T5LA 2FG0A 1KJ9A 2GPWA 5KFSA 4X64H 4EGJA 3V6JA 4DR7H 3I12A 1EUDB 2W6MA 2JA6A 4F0WA 2VUGA 1AUXA 2R86A 3K3VA 3KW0A 1RJRA 4ECXA 3Q8PB 1WR2A 1CE8A 2SCUB 3RIZA 5KFFA 2R92A 4EQ8A 2WP7A 3VPDA 1C3OA 4ED0A 3MFHA 4IRKA 2BR0A 5JVLA 4HNVA 4NLGA 4UCTA 3KHRA 4A3EG 2HJWA 2OWOA 3BAAA 1MZBA 2NVXA 4M7EA 4EEQA 5FPOA 2J9GA 2V4RA 2Q2TA 4RUAA 4X62H 1DV2A 4O3QA 2R7NA 2YS7A 1P8LA 4UCUA 4YAJB 2ASDA 1T94A 1Z2NX 2JEGA 2VUMA 4FQBA 3PR4A 2RDJA 2JA6G 1S03G 1I6UA 3Q1KA 1KJQA 4EG0A 3GTPA 5KFKA 1K1SA 2W6OA 4MV8A 3L4JA 5KFJA 1IOVA 4GKJH 2XIVA 4A3JG 4F4MA 3N43B 2QYZA 1JXLA 4AYBA 3O98A 3MWEA 4B3MH 5KT6A 1IOWA 4RUCA 5KFGA 5KFZA 4HNTA 2VA2A 5C5JA 4J9LA 2UVVA 5LP6F 3TINA 5KG6A 5DQGA 4IZOA 2ZDHA 4MA0A 4ZHQF 4LF5H 3A2ZA 5KFLA 3J81W 2UU9H 4R8UB 2UUBH 2R6FA 4IRDA 1KC7A 1GYFA 2VUMG 4RZQA 2UUCH 4ECQA 4J9NA 4FS2A 4PWQA 2RDIA 2VR1A 3RGZA 4LF4H 5FD6A 5DQIA 3BQ1A 3RBEA 4EFBA 2C2EA 4TV9F 2DPJA 5KFQA 4YP3A 4J9QA 4F4YA 4B3RH 5KKNB 4HPEA 4AYBE 4A3FG 2E2HA 2M05A 5DLGA 4DLKA 3BA9A 3J7AK 3V4ZA 4YHHH 4BY7G 2FK3A 2FLPA 4XYMB 4UCRA 3V6HA 2W6NA 3T1YH 4J9MA 2W71A 1I7LA 3GTLA 3GTKA 1Z2PX 4C5CA 4ZQIA 4JUZA 5FLMG 4DV5H 3TQ1A 1A9XA 1RYRA 2GPSA 4JV2A 3N44B 4IHJF 2XCPA 5J2TF 1FVIA 2ASJA 1UC8A 2XCLA 3SE7A 3RV3A 2JA8G 1DV1A 1RJPA 5EOYA 3GV5B 3GTQA 2IO9A 1XDNA 5KFWA 3UQ8A 5IYCG 5LXTF 1ZETA 2R7ZA 2NU6B 5KFIA 2FK2A 2HGSA 2YZMA 3R23A 2WAQA 5FPRA 3QFFA 5D1OA 3K3PA 4QW8A 5KFBA 4MTDA 3HOZG 2Y0SA 4BBSG 3RB0A 4LH6A 4A2BA 4K0KH 4DL3A 3N40P 4HNUA 1N56A 3LWBA 5IP9G 2FPGB 2VPQA 2W9AA 3QZ7A 3PBCA 1V9PA 4JV5H 4ZI7F 1TWCA 1GSAA 4TQSA 4O4HF 1Y14B 4ZOLF 1VAJA 3E5NA 4MV1A 3EPIA 4Q43A 3TQTA 1KJ8A 3MR5A 2FLNA 3ORRA 3VPBA 5C3EG 5L1LA 4ED7A 4O2AF 1GLVA 4Y8VB 1JIHA 1B6SA 1WH2A 3GLKA 2UXDH 2R8JA 4YB8B 1S0NA 2WE6A 4QWEA 3H40A 4MTEA 5LL6b 4TUYF 4BBRG 2JA5G 4JI1H 4HR7A 2WB1E 2MCTA 2W6QA 2CKZB 1Y1WG 1E4FT 4ECZA 3WO0A 2RGRA 2J6UA 4ETSA 1KJIA 4Q8EA 4A3BG 4DR1H 4YJ2F 2XGQA 2UUAH 4U7CA 3Q8QB 2X0SA 4GLXA 3NE0A 1EUCB 4MV3A 5CA0F 2WYOA 1E4GT 3R5FA 2C2DA 1JLLB 2KSWA 2EVRA 5CAEB 4RAYA 2VQDA 2V58A 4C2MA 4O2BF 4UCOA 4CC5A 4F4WA 5LYJF 4XX0B 3TIGA 3PR5B 2FLLA 5H80A 3H0GG 3RAQA 2Y0SE 4MV9A 1I3QA 4YY3H 5KG2A 3CVZA 4O3SA 3VPIA 1EZ1A 2VPMA 3LP8A 2VPSA 3PZPA 3KHLA 4RB3C 4ED6A 3MWMA 4F4XA 2Q2UA 4RNMA 4CT3A 3A30A 1RK6A 5KFVA 5KFXA 4ECSA 2V5AA 5EWFA 1I7NA 1CS0A 3OSPA 4Q4GX 3GT2A 2PN1A 3GIKA 2W9CB 2IMWP 4FGDA 4F4ZA 5IYDG 2J6SA 2R93A 4HFLA 4GC6A 5D1PA 5D8DA 2FPPB 3GIPA 4A3LG 2DZDA 1EHIA 4J9KA 5GONF 3HBLA 4I4TF 3RB6A 1B33N 2BQRA 1X9NA 1RK5A 4DUYH 3JSNA 4EBCA 4DL2A 2UVRA 2CW7A 1VBGA 5KG5A 1VS0A 2W57A 1TWGA 5DGBA 4FDYA 2W70A 4L1KA 4DR2H 3NGDA 3EBQA 4CSHA 4BXXG 4J32A 4YBZB 1Y1VG 3BG5A 3H4DA 4FBTA 3V6KA 4EFEA 2RF4A 4EBDA 1J5EH 4IR1A 5L1KA 1VBHA 5EDWA 5C1PA 3BQ2A 2ASLA 2BQ3A 3OUZA 3Q8SB 1DIKA 2YRWA 4HZ9A 5HBRB 3UFXB 3MR2A 2JA7A 4C5AA 4JURA 1SEIA 4O3RA 3HXLA 4U6PA 2ATLA 1S9FA 1TWAA 3RV4A 3MR6A 4TV8F 3G6YA 2WDTA 3GIIA 4R0KA 4O3NA 3FKIA 4AQYH 4I50F 1HNZH 3AYHB 1CQIB 1BXRA 3FDSA 3GIMA 2R7KA 2C28A 4IRCA 1N33H 4LJ1A 3MFIA 4RAZA 3M4IA 1S97A 4LH7A 1V51A 4RB0A 3PO2G 3ETJA 3L4KA 4NXMH 4ECVA 1FJGH 2JA7G 4BY1G 4DV6H 1V4YA 3MJFA 3RBDA 5IYZF 1T36A 5K2MA 1B04A 1E4EB 2RGVA 3F8NA 5KFCA 4LFCH 3PW4A 2ZDGA 4O3PA 4EYHB 4B3SH 1KJJA 1M6VA 4CC6A 1I50A 2UXCH 4I7HA 3GIJA 2R8HA 4ECWA 4IR9A 2PVPA 4LF8H 2XIGA 4Q4TA 3RJ0A 2R85A 4APMA 4FM9A 4ED3A 4EQAA 4J9PA 1KBLA 3KHHA 3M1UA 3H3VH 4EYIB 1UC9A 5L9XA 3G6XA 2HBWA 2HVQA 3C0FB 4R8UA 4ED1A 4A3IG 2FJZA 3L2PA 3U9SA 5KG7A 2E5LH 3T1HH 4LF7H 4FU0A 2NU9B 4PDBA 4F0VA 2JA5A 2AU0A 1S0OA 4CGKA 4JI6H 2FPIB 3MR3A 5LMUH 3U9TA 3OUUA 2B63G 2WTFA 2AGQA 5KG0A 4A3DG 1JDBB 3I86A 5LMNH 5EWEA 3H41A 1BGWA 3T5JA 2FK1A 4GC7A 5IT9W 2YYAA 3H20A 4J9OA 5KFAA 2YS6A 5KG3A 2W6PA 1N32H 3GTMA 2CZGA 2J6TA 5C44G 3H0GA 4JV1A 3KALA 4MA5A 3K5HA 1WSCA 4EEYA 4DV7H 3LMLA 3PN1A 5CB4F 5JH7F 4DV3H 3ETHA 2C2RA 4QW9A 4BWSC 3M9MB 1CQJB 3RF2A 2FE3A 1XMOH 4JI4H 4EGQA 4DV1H 2W6ZA 3IN5A 2YU9A 5IYBG 4MV7A 3Q2OA 1FKAH 5DG8A 1JKJB 3GIQA 3TIIA 3K5IA 3N6XA 4IWXA 2DPIA 3EPGA 3HOWG 5JVDF 4DV2H 1BJTA 2NU7B 5EZYF 4HFKA 3MWDA 4TQRA 1W93A 5KFOA 2UVWA 1XNQH 5IP7G 4A93G 2FKLA 4JI5H 4JV0A 3NPFA 4JYAH 4HQ6A 3RTXA 4HFFA 1SCUB 1PK8A 3T5KA 5I47A 3I4MG 3DF7A 1IBKH 2F4VH 1GSOA 1GSHA 5KFUA 4WBNF 4LF6H 1SYXB 5KG1A 2ZM6H 2W9CA 4WD3A 2B63A 4ME6A 3JRXA 3RB3A 2AGOA 4ECUA 4FGEA 3PO3G 3S0QA 5KFDA 2C00A 4QWBA 2YRXA 5BPFA 3RGXA 1N34H 1IBLH 2R8KA 2VOBA 2IOBA 3BJYA 4UCVA 4OLKA 2YCHA 2YZNA 2ZJTA 3BQ0A 2BQUA 4DR3H 3PW2A 3KTMA 3A2YA 2JEFA 1A0IA 3G6VA 2WAQE 2ALZA 2HVSA 2GLTA 3WO1A 2R7ZG 1O75A 5KFPA 2IOAA 3PVQA 2R82A 3T5HA 4O3OA 2IF6A 1DGSA 2JEJA 2I80A 4GKKH 4LF9H 2V4QA 5L1JA 4A3GG 5KT2A 3GILA 5C4XG 3RFCA 4A3CG 1EYZA 5C8YF 2V59A 5DGAA 5KT3A 4IAJA 3IG0A 4IWYA 2R8IA 5J2UF 3VPJA 3OHBA 2IO7A 5C1OA 2R8GA 5KFYA 4JI3H 4JI2H 4DL7A 2IA6A 4B3TH 4Q45A 2LRJA 4E4TA 4KHPH 2AQ4A 3HKZA 2FB9A 3KXYT 1T3NA 2JEIA 2ZDQA 2VA3A 2NVYA 1JDEA 2PMZA 4MV4A 2NU8B 2W8LA 1I94H 5KFEA 3FMAA 4A2AA 2XD4A 4I55F 4MV6A 1K1QA 4HYKA 3WNZA 3N42B 1TWHA 1XMQH 2PMZE 4M9UA 5DQHA 2QK4A 2V9WA 5F9LA 1C30A 3HOUG 2C22A 1XNRH 2CW8A 3RB4A 5FJ8G 4R7RA 5DG7A 3M9NB 4YJ3F 3J80W 4RU9A 4JI7H 1N48A 2XGPA 4A3KG 4DL5A 1HNWH 3GTJA 2K3AA 1M7JA 1VKZA 2C35B 3VPCA 4RZRA 3G8CA 4UCSA 2HVRA 5A2QW 2W7OA 5KX5F 1Y1VA 2VQEH 5D1OB 2DLNA 2R7LA 2DWCA 2DIKA 1R9TA 2YZGA 5L1IA 1RYSA 4XYLB 2K1GA 3BABA 4LFBH 3KAKA 1L2ZA 4LSXA 4RNNA 3R5HA 1HNXH 5JUMA 3HOVG 4J30A 3GIDA 2OH2A 4DL4A 5DG9A 3PVXA 1Y1WA 2IBKA 4JI8H 2R84A 5KG4A 4YQWA 1Z2OX 2FP4B 3OHAA 4NXNH 2R93G 2W7PA 1UNNC 5F9NA 1GO3E 5JQWA 5KT4A 3R5XA 4YAKB 3RAXA 1TAEA 2XCAA 4LFAH 2R92G 2IP4A 3SI8A 5IWAH 1RJQA 4O4IF 3M9OB 5DLFA 4QJFA 4FQAA 1JX4A 4DV4H 4O4LF 4DL6A 4LSAA 2I8CA 3HB9A 5T14A 3KHGA 3I4NG 4DR6H 4Q0YA 4YR0A 1AN7A 4X66H 1E4EA 1BNCA 4QIWE 5BMVF 1ULZA 4A3MG 5LOVF 1PX2A 4OX9H 5KFNA 4DR5H 3PW5A 1S0MA 1GGOA 1ZHSA 2W8KA 4DR4H 2E2IA 5KT7A 4HZBA 4FBUA 2R87A 4J9RA 4QWCA 1HR0H 5KFRA 1TA8A 5HV6A 4G3IA 1K83A 2CQYA 4X65H 3N8DA 4EBEA 4YR3A 4UFZA 1ZQ7A 1SFOA
chains in the Genus database with same CATH topology
4HZ9A 4DV5H 4FGEA 3PBIA 2IO8A 3N44B 1IBMH 4LMYA 3S0QA 1SEIA 1FVIA 3HXLA 1N34H 2UXBH 3RGXA 1IBLH 2IO9A 1S68A 1M0WA 2VOBA 5EOYA 2IOBA 1XDNA 4DV0H 3UQ8A 2WDTA 4UCVA 4OLKA 4R0KA 2YCHA 2ZJTA 1ZHQA 2HGSA 4DR3H 3EYYA 4AQYH 4JXBA 3A2YA 1HNZH 1A0IA 2HVSA 4EOBA 5FD5A 5FPRA 3JSLA 1O75A 5D1OA 2HHHH 2IOAA 3PVQA 4MTDA 1N33H 5BR8H 2VQFH 1DGSA 5FLXW 2IF6A 4GKKH 4FGIA 4LJ1A 4LH6A 3M4IA 4RAZA 4A2BA 4LF9H 4LH7A 3N40P 4RB0A 4K0KH 4RB2C 3L4KA 4NXMH 1FJGH 4DV6H 3PBCA 4IAJA 1V9PA 3OTOH 3IG0A 4JV5H 3BA8A 3JAMW 3VPJA 1B04A 4DUZH 2RGVA 3F8NA 4LFCH 2IO7A 4JI0H 4B3SH 3KAJA 4J0MA 4JI3H 4JI2H 4B3TH 4CC6A 2UXCH 2LRJA 4I7HA 4KHPH 3KXYT 4LF8H 2XIGA 4Q4TA 3RJ0A 4APMA 1N36H 3N41B 1M0TA 4FM9A 1I94H 1WH2A 4EQAA 2UXDH 3FMAA 4Q4NA 4A2AA 2WE6A 3M1UA 4RB1A 4MTEA 5LL6b 3N42B 2O03A 4JI1H 2HBWA 2FG0A 2HVQA 3C0FB 1XMQH 2MCTA 4X64H 3L2PA 4DR7H 1E4FT 2RGRA 2E5LH 3T1HH 4LF7H 4F0WA 4ETSA 2CW8A 2VUGA 3K3VA 1XNRH 4DR1H 4PDBA 4F0VA 4R7RA 3KW0A 2UUAH 4CGKA 3J80W 4JI6H 3RIZA 5LMUH 4GLXA 4JI7H 3NE0A 4EQ8A 1HNWH 2WYOA 1E4GT 2KSWA 2EVRA 2K3AA 4RAYA 4UCTA 3I86A 4UCSA 5LMNH 2HVRA 5A2QW 2VQEH 4UCOA 4CC5A 1BGWA 5D1OB 3H41A 2OWOA 5IT9W 3BAAA 1MZBA 3H20A 4M7EA 4EEQA 5FPOA 4MV9A 1N32H 4YY3H 2Q2TA 3CVZA 3BABA 2K1GA 4LFBH 3VPIA 3KAKA 4X62H 1L2ZA 4LSXA 1HNXH 2VPMA 1P8LA 3KALA 4UCUA 4FQBA 1Z2NX 2VPSA 4DV7H 2Q2UA 3LMLA 4RB3C 3MWMA 1S03G 1I6UA 3PN1A 4DV3H 4CT3A 3A30A 4JI8H 1Z2OX 4BWSC 4NXNH 3RF2A 2FE3A 3L4JA 1XMOH 4JI4H 4GKJH 4LFAH 2XIVA 4F4MA 1TAEA 4Q4GX 3N43B 4DV1H 3GT2A 5IWAH 3O98A 4B3MH 4MV7A 4FGDA 1FKAH 5D1PA 4FQAA 3N6XA 4DV4H 3A2ZA 4DV2H 1BJTA 4LSAA 4LF5H 1X9NA 3J81W 2UUBH 2UU9H 4DUYH 4DR6H 4Q0YA 3JSNA 1XNQH 1GYFA 2CW7A 1AN7A 4X66H 4RZQA 2UUCH 1VS0A 2W57A 4FDYA 4JI5H 4DR2H 4OX9H 3RGZA 4LF4H 3NPFA 4JYAH 5FD6A 3RTXA 4DR5H 4CSHA 4EFBA 1ZHSA 4DR4H 4HPEA 4B3RH 4HZBA 3DF7A 1HR0H 1IBKH 1TA8A 2F4VH 3BA9A 3J7AK 4YHHH 4EFEA 1J5EH 4LF6H 4UCRA 1SYXB 4X65H 2ZM6H 3T1YH 4UFZA 1Z2PX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NE0 A;  3O98 A;  4HZ9 A;  3VPJ A;  4FGD A;  4FGE A;  3PBI A;  2IO8 A;  4EQ8 A;  3S0Q A;  2IO7 A;  4FQA A;  2EVR A;  2K3A A;  3I86 A;  3A2Z A;  2IO9 A;  2LRJ A;  2VOB A;  2IOB A;  3H41 A;  4Q4T A;  4OLK A;  4R0K A;  4JXB A;  4FDY A;  4EQA A;  3A2Y A;  2K1G A;  3VPI A;  4Q4N A;  3M1U A;  3NPF A;  4CGK A;  2VPM A;  4CSH A;  4FQB A;  4EOB A;  4HPE A;  2HBW A;  2VPS A;  2FG0 A;  2IOA A;  3PVQ A;  4HZB A;  2IF6 A;  4FGI A;  4LJ1 A;  4CT3 A;  3A30 A;  4F0W A;  4F0V A;  3KW0 A;  2XIV A;  4F4M A;  3PBC A;  4Q4G X;  3GT2 A; 
#chains in the Genus database with same CATH topology
 3ORQ A;  2P0A A;  1W96 A;  3HOY G;  3PBI A;  2IO8 A;  1B6R A;  3Q8R B;  1IBM H;  4LMY A;  3PW7 A;  3JZI A;  1WCM A;  3JRW A;  5LA6 F;  1KEE A;  2UXB H;  5KFT A;  1S68 A;  4YR2 A;  3CQZ A;  1M0W A;  5BPH A;  1AUV A;  4DV0 H;  5CA1 F;  4ED8 A;  3HOX G;  1ZHQ A;  4JXB A;  3EYY A;  2UVU A;  3VMM A;  4J9S A;  3FKI G;  4QWD A;  4EOB A;  5FD5 A;  3OSN A;  3JSL A;  5KT5 A;  2HHH H;  3GTO A;  5BR8 H;  2VQF H;  2W9B B;  5FLX W;  2NUA B;  4Q44 A;  2OLS A;  4FGI A;  3GQC A;  4Q8F A;  1WCM G;  3GTG A;  4F50 A;  1TWF A;  4RB2 C;  4ECT A;  1S10 A;  4XZ3 B;  3GV7 B;  3PW0 A;  3H4B A;  1OWT A;  2FMA A;  4RNO A;  3OTO H;  2WB1 A;  3GV8 B;  3RUP A;  4ED2 A;  3BA8 A;  3JAM W;  2W9B A;  2PBZ A;  4DUZ H;  4MAM A;  4JI0 H;  2AGP A;  3KAJ A;  4J0M A;  4QIW A;  2I87 A;  2XC9 A;  4ECY A;  3QZ8 A;  4ECR A;  3HKZ E;  1N36 H;  3V4S A;  5KFM A;  3N41 B;  1M0T A;  4FS1 A;  2R7M A;  4QWA A;  5EWG A;  5KFH A;  4Q4N A;  2YL2 A;  4RB1 A;  4C5B A;  2YW2 A;  2O03 A;  3T5L A;  2FG0 A;  1KJ9 A;  2GPW A;  5KFS A;  4X64 H;  4EGJ A;  3V6J A;  4DR7 H;  3I12 A;  1EUD B;  2W6M A;  2JA6 A;  4F0W A;  2VUG A;  1AUX A;  2R86 A;  3K3V A;  3KW0 A;  1RJR A;  4ECX A;  3Q8P B;  1WR2 A;  1CE8 A;  2SCU B;  3RIZ A;  5KFF A;  2R92 A;  4EQ8 A;  2WP7 A;  3VPD A;  1C3O A;  4ED0 A;  3MFH A;  4IRK A;  2BR0 A;  5JVL A;  4HNV A;  4NLG A;  4UCT A;  3KHR A;  4A3E G;  2HJW A;  2OWO A;  3BAA A;  1MZB A;  2NVX A;  4M7E A;  4EEQ A;  5FPO A;  2J9G A;  2V4R A;  2Q2T A;  4RUA A;  4X62 H;  1DV2 A;  4O3Q A;  2R7N A;  2YS7 A;  1P8L A;  4UCU A;  4YAJ B;  2ASD A;  1T94 A;  1Z2N X;  2JEG A;  2VUM A;  4FQB A;  3PR4 A;  2RDJ A;  2JA6 G;  1S03 G;  1I6U A;  3Q1K A;  1KJQ A;  4EG0 A;  3GTP A;  5KFK A;  1K1S A;  2W6O A;  4MV8 A;  3L4J A;  5KFJ A;  1IOV A;  4GKJ H;  2XIV A;  4A3J G;  4F4M A;  3N43 B;  2QYZ A;  1JXL A;  4AYB A;  3O98 A;  3MWE A;  4B3M H;  5KT6 A;  1IOW A;  4RUC A;  5KFG A;  5KFZ A;  4HNT A;  2VA2 A;  5C5J A;  4J9L A;  2UVV A;  5LP6 F;  3TIN A;  5KG6 A;  5DQG A;  4IZO A;  2ZDH A;  4MA0 A;  4ZHQ F;  4LF5 H;  3A2Z A;  5KFL A;  3J81 W;  2UU9 H;  4R8U B;  2UUB H;  2R6F A;  4IRD A;  1KC7 A;  1GYF A;  2VUM G;  4RZQ A;  2UUC H;  4ECQ A;  4J9N A;  4FS2 A;  4PWQ A;  2RDI A;  2VR1 A;  3RGZ A;  4LF4 H;  5FD6 A;  5DQI A;  3BQ1 A;  3RBE A;  4EFB A;  2C2E A;  4TV9 F;  2DPJ A;  5KFQ A;  4YP3 A;  4J9Q A;  4F4Y A;  4B3R H;  5KKN B;  4HPE A;  4AYB E;  4A3F G;  2E2H A;  2M05 A;  5DLG A;  4DLK A;  3BA9 A;  3J7A K;  3V4Z A;  4YHH H;  4BY7 G;  2FK3 A;  2FLP A;  4XYM B;  4UCR A;  3V6H A;  2W6N A;  3T1Y H;  4J9M A;  2W71 A;  1I7L A;  3GTL A;  3GTK A;  1Z2P X;  4C5C A;  4ZQI A;  4JUZ A;  5FLM G;  4DV5 H;  3TQ1 A;  1A9X A;  1RYR A;  2GPS A;  4JV2 A;  3N44 B;  4IHJ F;  2XCP A;  5J2T F;  1FVI A;  2ASJ A;  1UC8 A;  2XCL A;  3SE7 A;  3RV3 A;  2JA8 G;  1DV1 A;  1RJP A;  5EOY A;  3GV5 B;  3GTQ A;  2IO9 A;  1XDN A;  5KFW A;  3UQ8 A;  5IYC G;  5LXT F;  1ZET A;  2R7Z A;  2NU6 B;  5KFI A;  2FK2 A;  2HGS A;  2YZM A;  3R23 A;  2WAQ A;  5FPR A;  3QFF A;  5D1O A;  3K3P A;  4QW8 A;  5KFB A;  4MTD A;  3HOZ G;  2Y0S A;  4BBS G;  3RB0 A;  4LH6 A;  4A2B A;  4K0K H;  4DL3 A;  3N40 P;  4HNU A;  1N56 A;  3LWB A;  5IP9 G;  2FPG B;  2VPQ A;  2W9A A;  3QZ7 A;  3PBC A;  1V9P A;  4JV5 H;  4ZI7 F;  1TWC A;  1GSA A;  4TQS A;  4O4H F;  1Y14 B;  4ZOL F;  1VAJ A;  3E5N A;  4MV1 A;  3EPI A;  4Q43 A;  3TQT A;  1KJ8 A;  3MR5 A;  2FLN A;  3ORR A;  3VPB A;  5C3E G;  5L1L A;  4ED7 A;  4O2A F;  1GLV A;  4Y8V B;  1JIH A;  1B6S A;  1WH2 A;  3GLK A;  2UXD H;  2R8J A;  4YB8 B;  1S0N A;  2WE6 A;  4QWE A;  3H40 A;  4MTE A;  5LL6 b;  4TUY F;  4BBR G;  2JA5 G;  4JI1 H;  4HR7 A;  2WB1 E;  2MCT A;  2W6Q A;  2CKZ B;  1Y1W G;  1E4F T;  4ECZ A;  3WO0 A;  2RGR A;  2J6U A;  4ETS A;  1KJI A;  4Q8E A;  4A3B G;  4DR1 H;  4YJ2 F;  2XGQ A;  2UUA H;  4U7C A;  3Q8Q B;  2X0S A;  4GLX A;  3NE0 A;  1EUC B;  4MV3 A;  5CA0 F;  2WYO A;  1E4G T;  3R5F A;  2C2D A;  1JLL B;  2KSW A;  2EVR A;  5CAE B;  4RAY A;  2VQD A;  2V58 A;  4C2M A;  4O2B F;  4UCO A;  4CC5 A;  4F4W A;  5LYJ F;  4XX0 B;  3TIG A;  3PR5 B;  2FLL A;  5H80 A;  3H0G G;  3RAQ A;  2Y0S E;  4MV9 A;  1I3Q A;  4YY3 H;  5KG2 A;  3CVZ A;  4O3S A;  3VPI A;  1EZ1 A;  2VPM A;  3LP8 A;  2VPS A;  3PZP A;  3KHL A;  4RB3 C;  4ED6 A;  3MWM A;  4F4X A;  2Q2U A;  4RNM A;  4CT3 A;  3A30 A;  1RK6 A;  5KFV A;  5KFX A;  4ECS A;  2V5A A;  5EWF A;  1I7N A;  1CS0 A;  3OSP A;  4Q4G X;  3GT2 A;  2PN1 A;  3GIK A;  2W9C B;  2IMW P;  4FGD A;  4F4Z A;  5IYD G;  2J6S A;  2R93 A;  4HFL A;  4GC6 A;  5D1P A;  5D8D A;  2FPP B;  3GIP A;  4A3L G;  2DZD A;  1EHI A;  4J9K A;  5GON F;  3HBL A;  4I4T F;  3RB6 A;  1B33 N;  2BQR A;  1X9N A;  1RK5 A;  4DUY H;  3JSN A;  4EBC A;  4DL2 A;  2UVR A;  2CW7 A;  1VBG A;  5KG5 A;  1VS0 A;  2W57 A;  1TWG A;  5DGB A;  4FDY A;  2W70 A;  4L1K A;  4DR2 H;  3NGD A;  3EBQ A;  4CSH A;  4BXX G;  4J32 A;  4YBZ B;  1Y1V G;  3BG5 A;  3H4D A;  4FBT A;  3V6K A;  4EFE A;  2RF4 A;  4EBD A;  1J5E H;  4IR1 A;  5L1K A;  1VBH A;  5EDW A;  5C1P A;  3BQ2 A;  2ASL A;  2BQ3 A;  3OUZ A;  3Q8S B;  1DIK A;  2YRW A;  4HZ9 A;  5HBR B;  3UFX B;  3MR2 A;  2JA7 A;  4C5A A;  4JUR A;  1SEI A;  4O3R A;  3HXL A;  4U6P A;  2ATL A;  1S9F A;  1TWA A;  3RV4 A;  3MR6 A;  4TV8 F;  3G6Y A;  2WDT A;  3GII A;  4R0K A;  4O3N A;  3FKI A;  4AQY H;  4I50 F;  1HNZ H;  3AYH B;  1CQI B;  1BXR A;  3FDS A;  3GIM A;  2R7K A;  2C28 A;  4IRC A;  1N33 H;  4LJ1 A;  3MFI A;  4RAZ A;  3M4I A;  1S97 A;  4LH7 A;  1V51 A;  4RB0 A;  3PO2 G;  3ETJ A;  3L4K A;  4NXM H;  4ECV A;  1FJG H;  2JA7 G;  4BY1 G;  4DV6 H;  1V4Y A;  3MJF A;  3RBD A;  5IYZ F;  1T36 A;  5K2M A;  1B04 A;  1E4E B;  2RGV A;  3F8N A;  5KFC A;  4LFC H;  3PW4 A;  2ZDG A;  4O3P A;  4EYH B;  4B3S H;  1KJJ A;  1M6V A;  4CC6 A;  1I50 A;  2UXC H;  4I7H A;  3GIJ A;  2R8H A;  4ECW A;  4IR9 A;  2PVP A;  4LF8 H;  2XIG A;  4Q4T A;  3RJ0 A;  2R85 A;  4APM A;  4FM9 A;  4ED3 A;  4EQA A;  4J9P A;  1KBL A;  3KHH A;  3M1U A;  3H3V H;  4EYI B;  1UC9 A;  5L9X A;  3G6X A;  2HBW A;  2HVQ A;  3C0F B;  4R8U A;  4ED1 A;  4A3I G;  2FJZ A;  3L2P A;  3U9S A;  5KG7 A;  2E5L H;  3T1H H;  4LF7 H;  4FU0 A;  2NU9 B;  4PDB A;  4F0V A;  2JA5 A;  2AU0 A;  1S0O A;  4CGK A;  4JI6 H;  2FPI B;  3MR3 A;  5LMU H;  3U9T A;  3OUU A;  2B63 G;  2WTF A;  2AGQ A;  5KG0 A;  4A3D G;  1JDB B;  3I86 A;  5LMN H;  5EWE A;  3H41 A;  1BGW A;  3T5J A;  2FK1 A;  4GC7 A;  5IT9 W;  2YYA A;  3H20 A;  4J9O A;  5KFA A;  2YS6 A;  5KG3 A;  2W6P A;  1N32 H;  3GTM A;  2CZG A;  2J6T A;  5C44 G;  3H0G A;  4JV1 A;  3KAL A;  4MA5 A;  3K5H A;  1WSC A;  4EEY A;  4DV7 H;  3LML A;  3PN1 A;  5CB4 F;  5JH7 F;  4DV3 H;  3ETH A;  2C2R A;  4QW9 A;  4BWS C;  3M9M B;  1CQJ B;  3RF2 A;  2FE3 A;  1XMO H;  4JI4 H;  4EGQ A;  4DV1 H;  2W6Z A;  3IN5 A;  2YU9 A;  5IYB G;  4MV7 A;  3Q2O A;  1FKA H;  5DG8 A;  1JKJ B;  3GIQ A;  3TII A;  3K5I A;  3N6X A;  4IWX A;  2DPI A;  3EPG A;  3HOW G;  5JVD F;  4DV2 H;  1BJT A;  2NU7 B;  5EZY F;  4HFK A;  3MWD A;  4TQR A;  1W93 A;  5KFO A;  2UVW A;  1XNQ H;  5IP7 G;  4A93 G;  2FKL A;  4JI5 H;  4JV0 A;  3NPF A;  4JYA H;  4HQ6 A;  3RTX A;  4HFF A;  1SCU B;  1PK8 A;  3T5K A;  5I47 A;  3I4M G;  3DF7 A;  1IBK H;  2F4V H;  1GSO A;  1GSH A;  5KFU A;  4WBN F;  4LF6 H;  1SYX B;  5KG1 A;  2ZM6 H;  2W9C A;  4WD3 A;  2B63 A;  4ME6 A;  3JRX A;  3RB3 A;  2AGO A;  4ECU A;  4FGE A;  3PO3 G;  3S0Q A;  5KFD A;  2C00 A;  4QWB A;  2YRX A;  5BPF A;  3RGX A;  1N34 H;  1IBL H;  2R8K A;  2VOB A;  2IOB A;  3BJY A;  4UCV A;  4OLK A;  2YCH A;  2YZN A;  2ZJT A;  3BQ0 A;  2BQU A;  4DR3 H;  3PW2 A;  3KTM A;  3A2Y A;  2JEF A;  1A0I A;  3G6V A;  2WAQ E;  2ALZ A;  2HVS A;  2GLT A;  3WO1 A;  2R7Z G;  1O75 A;  5KFP A;  2IOA A;  3PVQ A;  2R82 A;  3T5H A;  4O3O A;  2IF6 A;  1DGS A;  2JEJ A;  2I80 A;  4GKK H;  4LF9 H;  2V4Q A;  5L1J A;  4A3G G;  5KT2 A;  3GIL A;  5C4X G;  3RFC A;  4A3C G;  1EYZ A;  5C8Y F;  2V59 A;  5DGA A;  5KT3 A;  4IAJ A;  3IG0 A;  4IWY A;  2R8I A;  5J2U F;  3VPJ A;  3OHB A;  2IO7 A;  5C1O A;  2R8G A;  5KFY A;  4JI3 H;  4JI2 H;  4DL7 A;  2IA6 A;  4B3T H;  4Q45 A;  2LRJ A;  4E4T A;  4KHP H;  2AQ4 A;  3HKZ A;  2FB9 A;  3KXY T;  1T3N A;  2JEI A;  2ZDQ A;  2VA3 A;  2NVY A;  1JDE A;  2PMZ A;  4MV4 A;  2NU8 B;  2W8L A;  1I94 H;  5KFE A;  3FMA A;  4A2A A;  2XD4 A;  4I55 F;  4MV6 A;  1K1Q A;  4HYK A;  3WNZ A;  3N42 B;  1TWH A;  1XMQ H;  2PMZ E;  4M9U A;  5DQH A;  2QK4 A;  2V9W A;  5F9L A;  1C30 A;  3HOU G;  2C22 A;  1XNR H;  2CW8 A;  3RB4 A;  5FJ8 G;  4R7R A;  5DG7 A;  3M9N B;  4YJ3 F;  3J80 W;  4RU9 A;  4JI7 H;  1N48 A;  2XGP A;  4A3K G;  4DL5 A;  1HNW H;  3GTJ A;  2K3A A;  1M7J A;  1VKZ A;  2C35 B;  3VPC A;  4RZR A;  3G8C A;  4UCS A;  2HVR A;  5A2Q W;  2W7O A;  5KX5 F;  1Y1V A;  2VQE H;  5D1O B;  2DLN A;  2R7L A;  2DWC A;  2DIK A;  1R9T A;  2YZG A;  5L1I A;  1RYS A;  4XYL B;  2K1G A;  3BAB A;  4LFB H;  3KAK A;  1L2Z A;  4LSX A;  4RNN A;  3R5H A;  1HNX H;  5JUM A;  3HOV G;  4J30 A;  3GID A;  2OH2 A;  4DL4 A;  5DG9 A;  3PVX A;  1Y1W A;  2IBK A;  4JI8 H;  2R84 A;  5KG4 A;  4YQW A;  1Z2O X;  2FP4 B;  3OHA A;  4NXN H;  2R93 G;  2W7P A;  1UNN C;  5F9N A;  1GO3 E;  5JQW A;  5KT4 A;  3R5X A;  4YAK B;  3RAX A;  1TAE A;  2XCA A;  4LFA H;  2R92 G;  2IP4 A;  3SI8 A;  5IWA H;  1RJQ A;  4O4I F;  3M9O B;  5DLF A;  4QJF A;  4FQA A;  1JX4 A;  4DV4 H;  4O4L F;  4DL6 A;  4LSA A;  2I8C A;  3HB9 A;  5T14 A;  3KHG A;  3I4N G;  4DR6 H;  4Q0Y A;  4YR0 A;  1AN7 A;  4X66 H;  1E4E A;  1BNC A;  4QIW E;  5BMV F;  1ULZ A;  4A3M G;  5LOV F;  1PX2 A;  4OX9 H;  5KFN A;  4DR5 H;  3PW5 A;  1S0M A;  1GGO A;  1ZHS A;  2W8K A;  4DR4 H;  2E2I A;  5KT7 A;  4HZB A;  4FBU A;  2R87 A;  4J9R A;  4QWC A;  1HR0 H;  5KFR A;  1TA8 A;  5HV6 A;  4G3I A;  1K83 A;  2CQY A;  4X65 H;  3N8D A;  4EBE A;  4YR3 A;  4UFZ A;  1ZQ7 A;  1SFO A; 
#chains in the Genus database with same CATH homology
 4HZ9 A;  4DV5 H;  4FGE A;  3PBI A;  2IO8 A;  3N44 B;  1IBM H;  4LMY A;  3S0Q A;  1SEI A;  1FVI A;  3HXL A;  1N34 H;  2UXB H;  3RGX A;  1IBL H;  2IO9 A;  1S68 A;  1M0W A;  2VOB A;  5EOY A;  2IOB A;  1XDN A;  4DV0 H;  3UQ8 A;  2WDT A;  4UCV A;  4OLK A;  4R0K A;  2YCH A;  2ZJT A;  1ZHQ A;  2HGS A;  4DR3 H;  3EYY A;  4AQY H;  4JXB A;  3A2Y A;  1HNZ H;  1A0I A;  2HVS A;  4EOB A;  5FD5 A;  5FPR A;  3JSL A;  1O75 A;  5D1O A;  2HHH H;  2IOA A;  3PVQ A;  4MTD A;  1N33 H;  5BR8 H;  2VQF H;  1DGS A;  5FLX W;  2IF6 A;  4GKK H;  4FGI A;  4LJ1 A;  4LH6 A;  3M4I A;  4RAZ A;  4A2B A;  4LF9 H;  4LH7 A;  3N40 P;  4RB0 A;  4K0K H;  4RB2 C;  3L4K A;  4NXM H;  1FJG H;  4DV6 H;  3PBC A;  4IAJ A;  1V9P A;  3OTO H;  3IG0 A;  4JV5 H;  3BA8 A;  3JAM W;  3VPJ A;  1B04 A;  4DUZ H;  2RGV A;  3F8N A;  4LFC H;  2IO7 A;  4JI0 H;  4B3S H;  3KAJ A;  4J0M A;  4JI3 H;  4JI2 H;  4B3T H;  4CC6 A;  2UXC H;  2LRJ A;  4I7H A;  4KHP H;  3KXY T;  4LF8 H;  2XIG A;  4Q4T A;  3RJ0 A;  4APM A;  1N36 H;  3N41 B;  1M0T A;  4FM9 A;  1I94 H;  1WH2 A;  4EQA A;  2UXD H;  3FMA A;  4Q4N A;  4A2A A;  2WE6 A;  3M1U A;  4RB1 A;  4MTE A;  5LL6 b;  3N42 B;  2O03 A;  4JI1 H;  2HBW A;  2FG0 A;  2HVQ A;  3C0F B;  1XMQ H;  2MCT A;  4X64 H;  3L2P A;  4DR7 H;  1E4F T;  2RGR A;  2E5L H;  3T1H H;  4LF7 H;  4F0W A;  4ETS A;  2CW8 A;  2VUG A;  3K3V A;  1XNR H;  4DR1 H;  4PDB A;  4F0V A;  4R7R A;  3KW0 A;  2UUA H;  4CGK A;  3J80 W;  4JI6 H;  3RIZ A;  5LMU H;  4GLX A;  4JI7 H;  3NE0 A;  4EQ8 A;  1HNW H;  2WYO A;  1E4G T;  2KSW A;  2EVR A;  2K3A A;  4RAY A;  4UCT A;  3I86 A;  4UCS A;  5LMN H;  2HVR A;  5A2Q W;  2VQE H;  4UCO A;  4CC5 A;  1BGW A;  5D1O B;  3H41 A;  2OWO A;  5IT9 W;  3BAA A;  1MZB A;  3H20 A;  4M7E A;  4EEQ A;  5FPO A;  4MV9 A;  1N32 H;  4YY3 H;  2Q2T A;  3CVZ A;  3BAB A;  2K1G A;  4LFB H;  3VPI A;  3KAK A;  4X62 H;  1L2Z A;  4LSX A;  1HNX H;  2VPM A;  1P8L A;  3KAL A;  4UCU A;  4FQB A;  1Z2N X;  2VPS A;  4DV7 H;  2Q2U A;  3LML A;  4RB3 C;  3MWM A;  1S03 G;  1I6U A;  3PN1 A;  4DV3 H;  4CT3 A;  3A30 A;  4JI8 H;  1Z2O X;  4BWS C;  4NXN H;  3RF2 A;  2FE3 A;  3L4J A;  1XMO H;  4JI4 H;  4GKJ H;  4LFA H;  2XIV A;  4F4M A;  1TAE A;  4Q4G X;  3N43 B;  4DV1 H;  3GT2 A;  5IWA H;  3O98 A;  4B3M H;  4MV7 A;  4FGD A;  1FKA H;  5D1P A;  4FQA A;  3N6X A;  4DV4 H;  3A2Z A;  4DV2 H;  1BJT A;  4LSA A;  4LF5 H;  1X9N A;  3J81 W;  2UUB H;  2UU9 H;  4DUY H;  4DR6 H;  4Q0Y A;  3JSN A;  1XNQ H;  1GYF A;  2CW7 A;  1AN7 A;  4X66 H;  4RZQ A;  2UUC H;  1VS0 A;  2W57 A;  4FDY A;  4JI5 H;  4DR2 H;  4OX9 H;  3RGZ A;  4LF4 H;  3NPF A;  4JYA H;  5FD6 A;  3RTX A;  4DR5 H;  4CSH A;  4EFB A;  1ZHS A;  4DR4 H;  4HPE A;  4B3R H;  4HZB A;  3DF7 A;  1HR0 H;  1IBK H;  1TA8 A;  2F4V H;  3BA9 A;  3J7A K;  4YHH H;  4EFE A;  1J5E H;  4LF6 H;  4UCR A;  1SYX B;  4X65 H;  2ZM6 H;  3T1Y H;  4UFZ A;  1Z2P X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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