2IO9A

E. coli bifunctional glutathionylspermidine synthetase/amidase incomplex with mg2+ ,gsh and adp
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
609
structure length
601
Chain Sequence
APFGTLLGYAPGGVAIYSSDYSSDAVFRSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEENYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQIREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFPHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNIYQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
pubmed doi rcsb
molecule tags Ligase, hydrolase
source organism Escherichia coli
molecule keywords Bifunctional glutathionylspermidine synthetase/amidase
total genus 169
structure length 601
sequence length 609
chains with identical sequence B
ec nomenclature ec 3.5.1.78: Glutathionylspermidine amidase.
pdb deposition date 2006-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03738 GSP_synth Glutathionylspermidine synthase preATP-grasp
A PF05257 CHAP CHAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1720.10 Alpha Beta Alpha-Beta Complex endopeptidase fold (from Nostoc punctiforme) endopeptidase domain like (from Nostoc punctiforme) 2io9A01
2K3AA 4F0WA 3A30A 4FDYA 4EQAA 3A2YA 4FGDA 4FGEA 3NPFA 2VPSA 4F0VA 4HPEA 2EVRA 3S0QA 3PBIA 4JXBA 4FQBA 2IO9A 2VOBA 2IOAA 2LRJA 3A2ZA 4FQAA 3O98A 3GT2A 2FG0A 2HBWA 4HZBA 4Q4TA 4Q4GX 4EQ8A 3PVQA 4R0KA 4EOBA 4CSHA 3H41A 3I86A 4LJ1A 4OLKA 2IOBA 2IO7A 4CT3A 2VPMA 2XIVA 3KW0A 2IO8A 4FGIA 3VPJA 4CGKA 3VPIA 4Q4NA 3NE0A 2K1GA 4F4MA 2IF6A 4HZ9A 3M1UA 3PBCA
chains in the Genus database with same CATH superfamily
2K3AA 4JURA 4F0WA 4HFKA 3A30A 4FDYA 4EQAA 3A2YA 4FGDA 4HFFA 4FGEA 3NPFA 2VPSA 4F0VA 4HPEA 2EVRA 2WP7A 4HFLA 3S0QA 4J30A 3EBQA 3PBIA 4JXBA 4FQBA 2IO9A 2VOBA 2IOAA 2LRJA 3A2ZA 4FQAA 3O98A 3GT2A 4J32A 2FG0A 2HBWA 4HZBA 4Q4TA 4Q4GX 4EQ8A 3PVQA 4R0KA 4EOBA 4CSHA 3H41A 3I86A 4LJ1A 4OLKA 2IOBA 2IO7A 4CT3A 2VPMA 2XIVA 3KW0A 2IO8A 4FGIA 3VPJA 4CGKA 3VPIA 4Q4NA 3NE0A 2K1GA 4F4MA 2IF6A 4HZ9A 3M1UA 3PBCA
chains in the Genus database with same CATH topology
2K3AA 4F0WA 3A30A 4FDYA 4EQAA 3A2YA 4FGDA 4FGEA 3NPFA 2VPSA 4F0VA 4HPEA 2EVRA 3S0QA 3PBIA 4JXBA 4FQBA 2IO9A 2VOBA 2IOAA 2LRJA 3A2ZA 4FQAA 3O98A 3GT2A 2FG0A 2HBWA 4HZBA 4Q4TA 4Q4GX 4EQ8A 3PVQA 4R0KA 4EOBA 4CSHA 3H41A 3I86A 4LJ1A 4OLKA 2IOBA 2IO7A 4CT3A 2VPMA 2XIVA 3KW0A 2IO8A 4FGIA 3VPJA 4CGKA 3VPIA 4Q4NA 3NE0A 2K1GA 4F4MA 2IF6A 4HZ9A 3M1UA 3PBCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K3A A;  4F0W A;  3A30 A;  4FDY A;  4EQA A;  3A2Y A;  4FGD A;  4FGE A;  3NPF A;  2VPS A;  4F0V A;  4HPE A;  2EVR A;  3S0Q A;  3PBI A;  4JXB A;  4FQB A;  2IO9 A;  2VOB A;  2IOA A;  2LRJ A;  3A2Z A;  4FQA A;  3O98 A;  3GT2 A;  2FG0 A;  2HBW A;  4HZB A;  4Q4T A;  4Q4G X;  4EQ8 A;  3PVQ A;  4R0K A;  4EOB A;  4CSH A;  3H41 A;  3I86 A;  4LJ1 A;  4OLK A;  2IOB A;  2IO7 A;  4CT3 A;  2VPM A;  2XIV A;  3KW0 A;  2IO8 A;  4FGI A;  3VPJ A;  4CGK A;  3VPI A;  4Q4N A;  3NE0 A;  2K1G A;  4F4M A;  2IF6 A;  4HZ9 A;  3M1U A;  3PBC A; 
#chains in the Genus database with same CATH topology
 2K3A A;  4JUR A;  4F0W A;  4HFK A;  3A30 A;  4FDY A;  4EQA A;  3A2Y A;  4FGD A;  4HFF A;  4FGE A;  3NPF A;  2VPS A;  4F0V A;  4HPE A;  2EVR A;  2WP7 A;  4HFL A;  3S0Q A;  4J30 A;  3EBQ A;  3PBI A;  4JXB A;  4FQB A;  2IO9 A;  2VOB A;  2IOA A;  2LRJ A;  3A2Z A;  4FQA A;  3O98 A;  3GT2 A;  4J32 A;  2FG0 A;  2HBW A;  4HZB A;  4Q4T A;  4Q4G X;  4EQ8 A;  3PVQ A;  4R0K A;  4EOB A;  4CSH A;  3H41 A;  3I86 A;  4LJ1 A;  4OLK A;  2IOB A;  2IO7 A;  4CT3 A;  2VPM A;  2XIV A;  3KW0 A;  2IO8 A;  4FGI A;  3VPJ A;  4CGK A;  3VPI A;  4Q4N A;  3NE0 A;  2K1G A;  4F4M A;  2IF6 A;  4HZ9 A;  3M1U A;  3PBC A; 
#chains in the Genus database with same CATH homology
 2K3A A;  4F0W A;  3A30 A;  4FDY A;  4EQA A;  3A2Y A;  4FGD A;  4FGE A;  3NPF A;  2VPS A;  4F0V A;  4HPE A;  2EVR A;  3S0Q A;  3PBI A;  4JXB A;  4FQB A;  2IO9 A;  2VOB A;  2IOA A;  2LRJ A;  3A2Z A;  4FQA A;  3O98 A;  3GT2 A;  2FG0 A;  2HBW A;  4HZB A;  4Q4T A;  4Q4G X;  4EQ8 A;  3PVQ A;  4R0K A;  4EOB A;  4CSH A;  3H41 A;  3I86 A;  4LJ1 A;  4OLK A;  2IOB A;  2IO7 A;  4CT3 A;  2VPM A;  2XIV A;  3KW0 A;  2IO8 A;  4FGI A;  3VPJ A;  4CGK A;  3VPI A;  4Q4N A;  3NE0 A;  2K1G A;  4F4M A;  2IF6 A;  4HZ9 A;  3M1U A;  3PBC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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