2KJIA

A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
50
structure length
50
Chain Sequence
GETRACGRKLISLVMAVCGDLCNPQEGKDIATECCGNQCSDDYIRSACCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insulin worms its way into the spotlight.
pubmed doi rcsb
molecule tags Hormone
source organism Caenorhabditis elegans
molecule keywords Probable insulin-like peptide beta-type 5
total genus 9
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2009-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03488 Ins_beta Nematode insulin-related peptide beta type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 2kjiA00
4XSSB 2KQPA 2DSPI 1TGRA 1PMXA 3KR3D 1H59A 5L3MA 5L3LA 2DSRI 1GZRB 1GZYB 1B9GA 2GF1A 5L3NA 1WQJI 1BQTA 1ZEIA 6INSE 2JZQA 1IMXA 3GF1A 3LRIA 2LWZA 1GZZB 1EFEA 1H02B 1IGLA 1SJUA 2DSQC 2KJIA 2L29B
chains in the Genus database with same CATH superfamily
2L14B 3F2DA 4XSSB 2KQPA 2DSPI 1TGRA 1PMXA 3KR3D 1H59A 5L3MA 5L3LA 2DSRI 1GZRB 1GZYB 3F2BA 1B9GA 2GF1A 5L3NA 1WQJI 1BQTA 1ZEIA 6INSE 2JZQA 1IMXA 3GF1A 3LRIA 2LWZA 1GZZB 1EFEA 1H02B 1IGLA 1SJUA 2DSQC 2KJIA 2L29B 3F2CA
chains in the Genus database with same CATH topology
4XSSB 2KQPA 2DSPI 1TGRA 1PMXA 3KR3D 1H59A 5L3MA 5L3LA 2DSRI 1GZRB 1GZYB 1B9GA 2GF1A 5L3NA 1WQJI 1BQTA 1ZEIA 6INSE 2JZQA 1IMXA 3GF1A 3LRIA 2LWZA 1GZZB 1EFEA 1H02B 1IGLA 1SJUA 2DSQC 2KJIA 2L29B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSS B;  2KQP A;  2DSP I;  1TGR A;  1PMX A;  3KR3 D;  1H59 A;  5L3M A;  5L3L A;  2DSR I;  1GZR B;  1GZY B;  1B9G A;  2GF1 A;  5L3N A;  1WQJ I;  1BQT A;  1ZEI A;  6INS E;  2JZQ A;  1IMX A;  3GF1 A;  3LRI A;  2LWZ A;  1GZZ B;  1EFE A;  1H02 B;  1IGL A;  1SJU A;  2DSQ C;  2KJI A;  2L29 B; 
#chains in the Genus database with same CATH topology
 2L14 B;  3F2D A;  4XSS B;  2KQP A;  2DSP I;  1TGR A;  1PMX A;  3KR3 D;  1H59 A;  5L3M A;  5L3L A;  2DSR I;  1GZR B;  1GZY B;  3F2B A;  1B9G A;  2GF1 A;  5L3N A;  1WQJ I;  1BQT A;  1ZEI A;  6INS E;  2JZQ A;  1IMX A;  3GF1 A;  3LRI A;  2LWZ A;  1GZZ B;  1EFE A;  1H02 B;  1IGL A;  1SJU A;  2DSQ C;  2KJI A;  2L29 B;  3F2C A; 
#chains in the Genus database with same CATH homology
 4XSS B;  2KQP A;  2DSP I;  1TGR A;  1PMX A;  3KR3 D;  1H59 A;  5L3M A;  5L3L A;  2DSR I;  1GZR B;  1GZY B;  1B9G A;  2GF1 A;  5L3N A;  1WQJ I;  1BQT A;  1ZEI A;  6INS E;  2JZQ A;  1IMX A;  3GF1 A;  3LRI A;  2LWZ A;  1GZZ B;  1EFE A;  1H02 B;  1IGL A;  1SJU A;  2DSQ C;  2KJI A;  2L29 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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