2L14B

Structure of cbp nuclear coactivator binding domain in complex with p53 tad
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
49
structure length
49
Chain Sequence
PLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
pubmed doi rcsb
molecule keywords CREB-binding protein
molecule tags Protein binding
source organism Mus musculus
total genus 5
structure length 49
sequence length 49
ec nomenclature
pdb deposition date 2010-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF18521 TAD2 Transactivation domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.30 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like, subunit E 2l14B00
2L14B
chains in the Genus database with same CATH superfamily
2L14B 1ZEIA 2DSQC 1EFEA 1IGLA 1IMXA 1H02B 1WQJI 3F2CA 5L3MA 4XSSB 3F2BA 3F2DA 2LWZA 2L29B 2DSPI 1SJUA 1GZRB 2KQPA 5L3NA 1GZZB 1B9GA 1H59A 3LRIA 2DSRI 2KJIA 1PMXA 5L3LA 2GF1A 1GZYB 6INSE 2JZQA 1TGRA 3KR3D 1BQTA 3GF1A
chains in the Genus database with same CATH topology
3F2BA 2L14B 3F2DA 3F2CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L14 B; 
#chains in the Genus database with same CATH topology
 2L14 B;  1ZEI A;  2DSQ C;  1EFE A;  1IGL A;  1IMX A;  1H02 B;  1WQJ I;  3F2C A;  5L3M A;  4XSS B;  3F2B A;  3F2D A;  2LWZ A;  2L29 B;  2DSP I;  1SJU A;  1GZR B;  2KQP A;  5L3N A;  1GZZ B;  1B9G A;  1H59 A;  3LRI A;  2DSR I;  2KJI A;  1PMX A;  5L3L A;  2GF1 A;  1GZY B;  6INS E;  2JZQ A;  1TGR A;  3KR3 D;  1BQT A;  3GF1 A; 
#chains in the Genus database with same CATH homology
 3F2B A;  2L14 B;  3F2D A;  3F2C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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