2L14B

Structure of cbp nuclear coactivator binding domain in complex with p53 tad
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
49
structure length
49
Chain Sequence
PLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords CREB-binding protein
total genus 5
structure length 49
sequence length 49
ec nomenclature
pdb deposition date 2010-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF18521 TAD2 Transactivation domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.30 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like, subunit E 2l14B00
2L14B
chains in the Genus database with same CATH superfamily
2JZQA 2KJIA 5L3NA 1GZYB 1TGRA 1IMXA 1EFEA 1ZEIA 2LWZA 2L14B 1SJUA 3LRIA 1BQTA 1PMXA 2L29B 3F2DA 1GZZB 3GF1A 5L3MA 4XSSB 1WQJI 2DSRI 5L3LA 2KQPA 2DSPI 3F2BA 1H02B 1H59A 1GZRB 3F2CA 2GF1A 6INSE 1IGLA 1B9GA 2DSQC 3KR3D
chains in the Genus database with same CATH topology
3F2DA 2L14B 3F2BA 3F2CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L14 B; 
#chains in the Genus database with same CATH topology
 2JZQ A;  2KJI A;  5L3N A;  1GZY B;  1TGR A;  1IMX A;  1EFE A;  1ZEI A;  2LWZ A;  2L14 B;  1SJU A;  3LRI A;  1BQT A;  1PMX A;  2L29 B;  3F2D A;  1GZZ B;  3GF1 A;  5L3M A;  4XSS B;  1WQJ I;  2DSR I;  5L3L A;  2KQP A;  2DSP I;  3F2B A;  1H02 B;  1H59 A;  1GZR B;  3F2C A;  2GF1 A;  6INS E;  1IGL A;  1B9G A;  2DSQ C;  3KR3 D; 
#chains in the Genus database with same CATH homology
 3F2D A;  2L14 B;  3F2B A;  3F2C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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