2ZKDA

Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg dna
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
210
structure length
210
Chain Sequence
SGMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
pubmed doi rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3
total genus 65
structure length 210
sequence length 210
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 2zkdA00
4NJ5A 3OLNA 2ZO0B 2ZO2B 2ZKEA 2ZO1B 4PW5A 3FDEA 4PW7A 2ZKGA 2ZKFA 4PW6A 3F8IA 2PB7A 3F8JB 3BI7A 2ZKDA 3CLZA 3DWHA
chains in the Genus database with same CATH superfamily
4R28A 4NJ5A 3Q0DA 3OLNA 2ZO0B 2ZO2B 2ZKEA 2ZO1B 4PW5A 4RZLA 3Q0FA 4OC8A 3FDEA 4PW7A 2ZKGA 2ZKFA 4YGIA 4PW6A 3Q0BX 4F0PA 3F8IA 2PB7A 3F8JB 3BI7A 2ZKDA 3CLZA 3Q0CA 4F0QA 3DWHA
chains in the Genus database with same CATH topology
4NJ5A 3OLNA 2ZO0B 2ZO2B 2ZKEA 2ZO1B 4PW5A 3FDEA 4PW7A 2ZKGA 2ZKFA 4PW6A 3F8IA 2PB7A 3F8JB 3BI7A 2ZKDA 3CLZA 3DWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NJ5 A;  3OLN A;  2ZO0 B;  2ZO2 B;  2ZKE A;  2ZO1 B;  4PW5 A;  3FDE A;  4PW7 A;  2ZKG A;  2ZKF A;  4PW6 A;  3F8I A;  2PB7 A;  3F8J B;  3BI7 A;  2ZKD A;  3CLZ A;  3DWH A; 
#chains in the Genus database with same CATH topology
 4R28 A;  4NJ5 A;  3Q0D A;  3OLN A;  2ZO0 B;  2ZO2 B;  2ZKE A;  2ZO1 B;  4PW5 A;  4RZL A;  3Q0F A;  4OC8 A;  3FDE A;  4PW7 A;  2ZKG A;  2ZKF A;  4YGI A;  4PW6 A;  3Q0B X;  4F0P A;  3F8I A;  2PB7 A;  3F8J B;  3BI7 A;  2ZKD A;  3CLZ A;  3Q0C A;  4F0Q A;  3DWH A; 
#chains in the Genus database with same CATH homology
 4NJ5 A;  3OLN A;  2ZO0 B;  2ZO2 B;  2ZKE A;  2ZO1 B;  4PW5 A;  3FDE A;  4PW7 A;  2ZKG A;  2ZKF A;  4PW6 A;  3F8I A;  2PB7 A;  3F8J B;  3BI7 A;  2ZKD A;  3CLZ A;  3DWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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