3CLZA

The set and ring associated (sra) domain of uhrf1 bound to methylated dna
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
204
structure length
204
Chain Sequence
NHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase UHRF1
publication title Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
pubmed doi rcsb
source organism Homo sapiens
total genus 61
structure length 204
sequence length 204
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3clzA01
2ZKEA 3DWHA 4PW6A 4NJ5A 2ZO2B 3CLZA 3F8JB 4PW5A 3BI7A 2ZKFA 3FDEA 2PB7A 2ZKGA 4PW7A 2ZO1B 2ZKDA 3OLNA 2ZO0B 3F8IA
chains in the Genus database with same CATH superfamily
2ZKEA 4OC8A 3DWHA 3Q0BX 4R28A 4PW6A 3Q0FA 4NJ5A 4YGIA 4RZLA 3Q0CA 2ZO2B 3CLZA 3F8JB 4PW5A 3BI7A 4F0PA 2ZKFA 3Q0DA 3FDEA 2PB7A 2ZKGA 4PW7A 4F0QA 2ZO1B 2ZKDA 3OLNA 2ZO0B 3F8IA
chains in the Genus database with same CATH topology
2ZKEA 3DWHA 4PW6A 4NJ5A 2ZO2B 3CLZA 3F8JB 4PW5A 3BI7A 2ZKFA 3FDEA 2PB7A 2ZKGA 4PW7A 2ZO1B 2ZKDA 3OLNA 2ZO0B 3F8IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKE A;  3DWH A;  4PW6 A;  4NJ5 A;  2ZO2 B;  3CLZ A;  3F8J B;  4PW5 A;  3BI7 A;  2ZKF A;  3FDE A;  2PB7 A;  2ZKG A;  4PW7 A;  2ZO1 B;  2ZKD A;  3OLN A;  2ZO0 B;  3F8I A; 
#chains in the Genus database with same CATH topology
 2ZKE A;  4OC8 A;  3DWH A;  3Q0B X;  4R28 A;  4PW6 A;  3Q0F A;  4NJ5 A;  4YGI A;  4RZL A;  3Q0C A;  2ZO2 B;  3CLZ A;  3F8J B;  4PW5 A;  3BI7 A;  4F0P A;  2ZKF A;  3Q0D A;  3FDE A;  2PB7 A;  2ZKG A;  4PW7 A;  4F0Q A;  2ZO1 B;  2ZKD A;  3OLN A;  2ZO0 B;  3F8I A; 
#chains in the Genus database with same CATH homology
 2ZKE A;  3DWH A;  4PW6 A;  4NJ5 A;  2ZO2 B;  3CLZ A;  3F8J B;  4PW5 A;  3BI7 A;  2ZKF A;  3FDE A;  2PB7 A;  2ZKG A;  4PW7 A;  2ZO1 B;  2ZKD A;  3OLN A;  2ZO0 B;  3F8I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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