2ZKFA

Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg dna
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
209
structure length
209
Chain Sequence
GMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
pubmed doi rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords E3 ubiquitin-protein ligase UHRF1
total genus 57
structure length 209
sequence length 209
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 2zkfA00
4PW7A 4NJ5A 2ZO1B 3BI7A 2PB7A 2ZKGA 3F8JB 4PW6A 2ZKDA 2ZKFA 3OLNA 3CLZA 2ZKEA 2ZO0B 4PW5A 2ZO2B 3DWHA 3FDEA 3F8IA
chains in the Genus database with same CATH superfamily
4PW7A 4NJ5A 2ZO1B 4YGIA 3BI7A 3Q0DA 2PB7A 3Q0CA 4F0PA 2ZKGA 3F8JB 4OC8A 4PW6A 2ZKDA 2ZKFA 3OLNA 4F0QA 3Q0FA 4RZLA 3CLZA 2ZKEA 4R28A 3Q0BX 2ZO0B 4PW5A 2ZO2B 3DWHA 3FDEA 3F8IA
chains in the Genus database with same CATH topology
4PW7A 4NJ5A 2ZO1B 3BI7A 2PB7A 2ZKGA 3F8JB 4PW6A 2ZKDA 2ZKFA 3OLNA 3CLZA 2ZKEA 2ZO0B 4PW5A 2ZO2B 3DWHA 3FDEA 3F8IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PW7 A;  4NJ5 A;  2ZO1 B;  3BI7 A;  2PB7 A;  2ZKG A;  3F8J B;  4PW6 A;  2ZKD A;  2ZKF A;  3OLN A;  3CLZ A;  2ZKE A;  2ZO0 B;  4PW5 A;  2ZO2 B;  3DWH A;  3FDE A;  3F8I A; 
#chains in the Genus database with same CATH topology
 4PW7 A;  4NJ5 A;  2ZO1 B;  4YGI A;  3BI7 A;  3Q0D A;  2PB7 A;  3Q0C A;  4F0P A;  2ZKG A;  3F8J B;  4OC8 A;  4PW6 A;  2ZKD A;  2ZKF A;  3OLN A;  4F0Q A;  3Q0F A;  4RZL A;  3CLZ A;  2ZKE A;  4R28 A;  3Q0B X;  2ZO0 B;  4PW5 A;  2ZO2 B;  3DWH A;  3FDE A;  3F8I A; 
#chains in the Genus database with same CATH homology
 4PW7 A;  4NJ5 A;  2ZO1 B;  3BI7 A;  2PB7 A;  2ZKG A;  3F8J B;  4PW6 A;  2ZKD A;  2ZKF A;  3OLN A;  3CLZ A;  2ZKE A;  2ZO0 B;  4PW5 A;  2ZO2 B;  3DWH A;  3FDE A;  3F8I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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