3F8JB

Mouse uhrf1 sra domain bound with hemi-methylated cpg, crystal structure in space group c222(1)
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
206
structure length
206
Chain Sequence
IVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
pubmed rcsb
molecule keywords E3 ubiquitin-protein ligase UHRF1
molecule tags Ligase/dna
source organism Mus musculus
total genus 64
structure length 206
sequence length 206
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3f8jB01
3CLZA 4PW7A 2PB7A 4PW6A 3OLNA 2ZKDA 2ZO1B 3F8JB 2ZKGA 2ZO2B 3F8IA 4NJ5A 2ZKFA 3FDEA 2ZKEA 4PW5A 3BI7A 2ZO0B 3DWHA
chains in the Genus database with same CATH superfamily
3Q0FA 3CLZA 4RZLA 4PW7A 2PB7A 4F0QA 4PW6A 3OLNA 2ZKDA 4OC8A 2ZO1B 4R28A 3DWHA 3F8JB 4F0PA 2ZKGA 2ZO2B 3F8IA 4NJ5A 2ZKFA 3Q0BX 3Q0DA 3FDEA 3Q0CA 2ZKEA 4PW5A 3BI7A 2ZO0B 4YGIA
chains in the Genus database with same CATH topology
3CLZA 4PW7A 2PB7A 4PW6A 3OLNA 2ZKDA 2ZO1B 3F8JB 2ZKGA 2ZO2B 3F8IA 4NJ5A 2ZKFA 3FDEA 2ZKEA 4PW5A 3BI7A 2ZO0B 3DWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CLZ A;  4PW7 A;  2PB7 A;  4PW6 A;  3OLN A;  2ZKD A;  2ZO1 B;  3F8J B;  2ZKG A;  2ZO2 B;  3F8I A;  4NJ5 A;  2ZKF A;  3FDE A;  2ZKE A;  4PW5 A;  3BI7 A;  2ZO0 B;  3DWH A; 
#chains in the Genus database with same CATH topology
 3Q0F A;  3CLZ A;  4RZL A;  4PW7 A;  2PB7 A;  4F0Q A;  4PW6 A;  3OLN A;  2ZKD A;  4OC8 A;  2ZO1 B;  4R28 A;  3DWH A;  3F8J B;  4F0P A;  2ZKG A;  2ZO2 B;  3F8I A;  4NJ5 A;  2ZKF A;  3Q0B X;  3Q0D A;  3FDE A;  3Q0C A;  2ZKE A;  4PW5 A;  3BI7 A;  2ZO0 B;  4YGI A; 
#chains in the Genus database with same CATH homology
 3CLZ A;  4PW7 A;  2PB7 A;  4PW6 A;  3OLN A;  2ZKD A;  2ZO1 B;  3F8J B;  2ZKG A;  2ZO2 B;  3F8I A;  4NJ5 A;  2ZKF A;  3FDE A;  2ZKE A;  4PW5 A;  3BI7 A;  2ZO0 B;  3DWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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