3FDEA

Mouse uhrf1 sra domain bound with hemi-methylated cpg dna, crystal structure in space group c222(1) at 1.4 a resolution
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
209
structure length
209
Chain Sequence
MPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
pubmed rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords E3 ubiquitin-protein ligase UHRF1
total genus 62
structure length 209
sequence length 209
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3fdeA01
2ZKEA 2ZO0B 4PW6A 3OLNA 4PW7A 3DWHA 4NJ5A 2ZO1B 2ZO2B 3CLZA 3FDEA 3F8JB 2ZKDA 4PW5A 2ZKGA 3BI7A 3F8IA 2PB7A 2ZKFA
chains in the Genus database with same CATH superfamily
3Q0CA 2ZKEA 3Q0BX 2ZO0B 4PW6A 4YGIA 3Q0DA 4RZLA 3OLNA 4PW7A 3DWHA 4NJ5A 2ZO1B 2ZO2B 3CLZA 3FDEA 3Q0FA 4F0QA 3F8JB 2ZKDA 4OC8A 4PW5A 2ZKGA 3BI7A 4F0PA 3F8IA 2PB7A 2ZKFA 4R28A
chains in the Genus database with same CATH topology
2ZKEA 2ZO0B 4PW6A 3OLNA 4PW7A 3DWHA 4NJ5A 2ZO1B 2ZO2B 3CLZA 3FDEA 3F8JB 2ZKDA 4PW5A 2ZKGA 3BI7A 3F8IA 2PB7A 2ZKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKE A;  2ZO0 B;  4PW6 A;  3OLN A;  4PW7 A;  3DWH A;  4NJ5 A;  2ZO1 B;  2ZO2 B;  3CLZ A;  3FDE A;  3F8J B;  2ZKD A;  4PW5 A;  2ZKG A;  3BI7 A;  3F8I A;  2PB7 A;  2ZKF A; 
#chains in the Genus database with same CATH topology
 3Q0C A;  2ZKE A;  3Q0B X;  2ZO0 B;  4PW6 A;  4YGI A;  3Q0D A;  4RZL A;  3OLN A;  4PW7 A;  3DWH A;  4NJ5 A;  2ZO1 B;  2ZO2 B;  3CLZ A;  3FDE A;  3Q0F A;  4F0Q A;  3F8J B;  2ZKD A;  4OC8 A;  4PW5 A;  2ZKG A;  3BI7 A;  4F0P A;  3F8I A;  2PB7 A;  2ZKF A;  4R28 A; 
#chains in the Genus database with same CATH homology
 2ZKE A;  2ZO0 B;  4PW6 A;  3OLN A;  4PW7 A;  3DWH A;  4NJ5 A;  2ZO1 B;  2ZO2 B;  3CLZ A;  3FDE A;  3F8J B;  2ZKD A;  4PW5 A;  2ZKG A;  3BI7 A;  3F8I A;  2PB7 A;  2ZKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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