3GF1A

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
pubmed doi rcsb
molecule tags Growth factor
source organism Homo sapiens
molecule keywords INSULIN-LIKE GROWTH FACTOR I
total genus 23
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1991-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 3gf1A00
2LWZA 1BQTA 1TGRA 1PMXA 1ZEIA 2KQPA 2KJIA 1SJUA 1IMXA 1EFEA 1WQJI 3GF1A 2DSPI 2DSRI 2GF1A 5L3MA 2L29B 1H02B 1GZYB 5L3LA 6INSE 1H59A 2DSQC 2JZQA 3LRIA 3KR3D 5L3NA 1IGLA 1GZZB 1B9GA 4XSSB 1GZRB
chains in the Genus database with same CATH superfamily
2LWZA 3F2CA 1BQTA 1TGRA 1PMXA 1ZEIA 2KQPA 2KJIA 3F2DA 1SJUA 1IMXA 1EFEA 1WQJI 3GF1A 2DSPI 2DSRI 2GF1A 5L3MA 2L29B 1H02B 1GZYB 5L3LA 6INSE 1H59A 2DSQC 2L14B 2JZQA 3LRIA 3KR3D 5L3NA 3F2BA 1IGLA 1GZZB 1B9GA 4XSSB 1GZRB
chains in the Genus database with same CATH topology
2LWZA 1BQTA 1TGRA 1PMXA 1ZEIA 2KQPA 2KJIA 1SJUA 1IMXA 1EFEA 1WQJI 3GF1A 2DSPI 2DSRI 2GF1A 5L3MA 2L29B 1H02B 1GZYB 5L3LA 6INSE 1H59A 2DSQC 2JZQA 3LRIA 3KR3D 5L3NA 1IGLA 1GZZB 1B9GA 4XSSB 1GZRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LWZ A;  1BQT A;  1TGR A;  1PMX A;  1ZEI A;  2KQP A;  2KJI A;  1SJU A;  1IMX A;  1EFE A;  1WQJ I;  3GF1 A;  2DSP I;  2DSR I;  2GF1 A;  5L3M A;  2L29 B;  1H02 B;  1GZY B;  5L3L A;  6INS E;  1H59 A;  2DSQ C;  2JZQ A;  3LRI A;  3KR3 D;  5L3N A;  1IGL A;  1GZZ B;  1B9G A;  4XSS B;  1GZR B; 
#chains in the Genus database with same CATH topology
 2LWZ A;  3F2C A;  1BQT A;  1TGR A;  1PMX A;  1ZEI A;  2KQP A;  2KJI A;  3F2D A;  1SJU A;  1IMX A;  1EFE A;  1WQJ I;  3GF1 A;  2DSP I;  2DSR I;  2GF1 A;  5L3M A;  2L29 B;  1H02 B;  1GZY B;  5L3L A;  6INS E;  1H59 A;  2DSQ C;  2L14 B;  2JZQ A;  3LRI A;  3KR3 D;  5L3N A;  3F2B A;  1IGL A;  1GZZ B;  1B9G A;  4XSS B;  1GZR B; 
#chains in the Genus database with same CATH homology
 2LWZ A;  1BQT A;  1TGR A;  1PMX A;  1ZEI A;  2KQP A;  2KJI A;  1SJU A;  1IMX A;  1EFE A;  1WQJ I;  3GF1 A;  2DSP I;  2DSR I;  2GF1 A;  5L3M A;  2L29 B;  1H02 B;  1GZY B;  5L3L A;  6INS E;  1H59 A;  2DSQ C;  2JZQ A;  3LRI A;  3KR3 D;  5L3N A;  1IGL A;  1GZZ B;  1B9G A;  4XSS B;  1GZR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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