3GF1A

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
pubmed doi rcsb
molecule tags Growth factor
source organism Homo sapiens
molecule keywords INSULIN-LIKE GROWTH FACTOR I
total genus 23
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1991-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 3gf1A00
4XSSB 2DSRI 2L29B 2GF1A 5L3NA 5L3MA 1IGLA 2JZQA 2KQPA 1IMXA 1H02B 1BQTA 3LRIA 1SJUA 1ZEIA 3KR3D 1EFEA 1WQJI 1GZRB 1GZZB 2DSPI 2KJIA 1TGRA 1PMXA 3GF1A 1GZYB 2DSQC 6INSE 1H59A 5L3LA 1B9GA 2LWZA
chains in the Genus database with same CATH superfamily
4XSSB 2DSRI 2L29B 2GF1A 3F2DA 5L3NA 5L3MA 1IGLA 2JZQA 2KQPA 1IMXA 1H02B 1BQTA 3F2CA 3LRIA 1SJUA 1ZEIA 3KR3D 1EFEA 1WQJI 1GZRB 1GZZB 2DSPI 2KJIA 1TGRA 1PMXA 3GF1A 3F2BA 1GZYB 2DSQC 6INSE 1H59A 5L3LA 1B9GA 2LWZA 2L14B
chains in the Genus database with same CATH topology
4XSSB 2DSRI 2L29B 2GF1A 5L3NA 5L3MA 1IGLA 2JZQA 2KQPA 1IMXA 1H02B 1BQTA 3LRIA 1SJUA 1ZEIA 3KR3D 1EFEA 1WQJI 1GZRB 1GZZB 2DSPI 2KJIA 1TGRA 1PMXA 3GF1A 1GZYB 2DSQC 6INSE 1H59A 5L3LA 1B9GA 2LWZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSS B;  2DSR I;  2L29 B;  2GF1 A;  5L3N A;  5L3M A;  1IGL A;  2JZQ A;  2KQP A;  1IMX A;  1H02 B;  1BQT A;  3LRI A;  1SJU A;  1ZEI A;  3KR3 D;  1EFE A;  1WQJ I;  1GZR B;  1GZZ B;  2DSP I;  2KJI A;  1TGR A;  1PMX A;  3GF1 A;  1GZY B;  2DSQ C;  6INS E;  1H59 A;  5L3L A;  1B9G A;  2LWZ A; 
#chains in the Genus database with same CATH topology
 4XSS B;  2DSR I;  2L29 B;  2GF1 A;  3F2D A;  5L3N A;  5L3M A;  1IGL A;  2JZQ A;  2KQP A;  1IMX A;  1H02 B;  1BQT A;  3F2C A;  3LRI A;  1SJU A;  1ZEI A;  3KR3 D;  1EFE A;  1WQJ I;  1GZR B;  1GZZ B;  2DSP I;  2KJI A;  1TGR A;  1PMX A;  3GF1 A;  3F2B A;  1GZY B;  2DSQ C;  6INS E;  1H59 A;  5L3L A;  1B9G A;  2LWZ A;  2L14 B; 
#chains in the Genus database with same CATH homology
 4XSS B;  2DSR I;  2L29 B;  2GF1 A;  5L3N A;  5L3M A;  1IGL A;  2JZQ A;  2KQP A;  1IMX A;  1H02 B;  1BQT A;  3LRI A;  1SJU A;  1ZEI A;  3KR3 D;  1EFE A;  1WQJ I;  1GZR B;  1GZZ B;  2DSP I;  2KJI A;  1TGR A;  1PMX A;  3GF1 A;  1GZY B;  2DSQ C;  6INS E;  1H59 A;  5L3L A;  1B9G A;  2LWZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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