The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
17
|
sequence length |
60
|
structure length |
60
|
Chain Sequence |
SETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo.
pubmed doi rcsb |
| molecule tags |
Immune system
|
| source organism |
Homo sapiens
|
| molecule keywords |
Insulin-like growth factor II
|
| total genus |
17
|
| structure length |
60
|
| sequence length |
60
|
| ec nomenclature | |
| pdb deposition date | 2009-11-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| D | PF00049 | Insulin | Insulin/IGF/Relaxin family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Insulin-like, subunit E | Insulin-like |
#chains in the Genus database with same CATH superfamily 3LRI A; 1EFE A; 1B9G A; 2JZQ A; 6INS E; 5L3L A; 1GZZ B; 3KR3 D; 4XSS B; 2DSQ C; 1WQJ I; 5L3M A; 1PMX A; 1IMX A; 1GZY B; 3GF1 A; 1ZEI A; 2GF1 A; 2DSR I; 1H02 B; 2KJI A; 1GZR B; 1SJU A; 1BQT A; 1IGL A; 5L3N A; 2DSP I; 1H59 A; 2KQP A; 1TGR A; 2L29 B; 2LWZ A; #chains in the Genus database with same CATH topology 3F2C A; 3LRI A; 1EFE A; 1B9G A; 2JZQ A; 2L14 B; 6INS E; 5L3L A; 1GZZ B; 3KR3 D; 4XSS B; 2DSQ C; 1WQJ I; 5L3M A; 1PMX A; 1IMX A; 1GZY B; 3GF1 A; 1ZEI A; 2GF1 A; 2DSR I; 1H02 B; 2KJI A; 1GZR B; 3F2B A; 1SJU A; 1BQT A; 1IGL A; 3F2D A; 5L3N A; 2DSP I; 1H59 A; 2KQP A; 1TGR A; 2L29 B; 2LWZ A; #chains in the Genus database with same CATH homology 3LRI A; 1EFE A; 1B9G A; 2JZQ A; 6INS E; 5L3L A; 1GZZ B; 3KR3 D; 4XSS B; 2DSQ C; 1WQJ I; 5L3M A; 1PMX A; 1IMX A; 1GZY B; 3GF1 A; 1ZEI A; 2GF1 A; 2DSR I; 1H02 B; 2KJI A; 1GZR B; 1SJU A; 1BQT A; 1IGL A; 5L3N A; 2DSP I; 1H59 A; 2KQP A; 1TGR A; 2L29 B; 2LWZ A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
