3QXL | Genus

Total Genus 102

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	102
sequence length	245
structure length	245
Chain Sequence	FDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a. pubmed doi rcsb
molecule keywords	Ras-specific guanine nucleotide-releasing factor RalGPS1
total genus	102
structure length	245
sequence length	245
chains with identical sequence	B
ec nomenclature
pdb deposition date	2011-03-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00617	RasGEF	RasGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.840.10	Mainly Alpha	Orthogonal Bundle	Son of Sevenless (SoS) protein; Chain S, domain 2	Ras guanine-nucleotide exchange factors catalytic domain	3qxlA00

4F7ZA 4MGKE 2BYVE 4MH0E 1NVXS 1NVVS 4URYS 1NVUS 4L9MA 4NYIS 4US0S 4URUS 2II0A 3QXLA 4NYJS 4URVS 1BKDS 4US1S 1XD2C 5CM8A 4URWS 4US2S 1XD4A 4JGWA 4URXS 1NVWS 3T6GA 4URZS 2IJES 3T6AA 4MGYE 5CM9A 3KSYA 4MGZE 4NYMS 3CF6E 4MGIE
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4F7Z A;  4MGK E;  2BYV E;  4MH0 E;  1NVX S;  1NVV S;  4URY S;  1NVU S;  4L9M A;  4NYI S;  4US0 S;  4URU S;  2II0 A;  3QXL A;  4NYJ S;  4URV S;  1BKD S;  4US1 S;  1XD2 C;  5CM8 A;  4URW S;  4US2 S;  1XD4 A;  4JGW A;  4URX S;  1NVW S;  3T6G A;  4URZ S;  2IJE S;  3T6A A;  4MGY E;  5CM9 A;  3KSY A;  4MGZ E;  4NYM S;  3CF6 E;  4MGI E; 
#chains in the Genus database with same CATH topology
 4F7Z A;  4MGK E;  2BYV E;  4MH0 E;  1NVX S;  1NVV S;  4URY S;  1NVU S;  4L9M A;  4NYI S;  4US0 S;  4URU S;  2II0 A;  3QXL A;  4NYJ S;  4URV S;  1BKD S;  4US1 S;  1XD2 C;  5CM8 A;  4URW S;  4US2 S;  1XD4 A;  4JGW A;  4URX S;  1NVW S;  3T6G A;  4URZ S;  2IJE S;  3T6A A;  4MGY E;  5CM9 A;  3KSY A;  4MGZ E;  4NYM S;  3CF6 E;  4MGI E; 
#chains in the Genus database with same CATH homology
 4F7Z A;  4MGK E;  2BYV E;  4MH0 E;  1NVX S;  1NVV S;  4URY S;  1NVU S;  4L9M A;  4NYI S;  4US0 S;  4URU S;  2II0 A;  3QXL A;  4NYJ S;  4URV S;  1BKD S;  4US1 S;  1XD2 C;  5CM8 A;  4URW S;  4US2 S;  1XD4 A;  4JGW A;  4URX S;  1NVW S;  3T6G A;  4URZ S;  2IJE S;  3T6A A;  4MGY E;  5CM9 A;  3KSY A;  4MGZ E;  4NYM S;  3CF6 E;  4MGI E;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3QXLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations