The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
219
|
sequence length |
681
|
structure length |
627
|
Chain Sequence |
MRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGQLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNHQDVRSYVRQLNVIDNQRTLSQMSHRLEP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Rap guanine nucleotide exchange factor 4
|
| publication title |
Selective activation of Epac1 and Epac2
rcsb |
| source organism |
Mus musculus
|
| molecule tags |
Signaling protein/gtp-binding protein
|
| total genus |
219
|
| structure length |
627
|
| sequence length |
681
|
| ec nomenclature | |
| pdb deposition date | 2013-08-28 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| E | PF00027 | cNMP_binding | Cyclic nucleotide-binding domain |
| E | PF00617 | RasGEF | RasGEF domain |
| E | PF00618 | RasGEF_N | RasGEF N-terminal motif |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Helicase, Ruva Protein; domain 3 | Helicase, Ruva Protein; domain 3 | ||
| Mainly Alpha | Orthogonal Bundle | Son of Sevenless (SoS) protein; Chain S, domain 2 | Ras guanine-nucleotide exchange factors catalytic domain | ||
| Mainly Alpha | Up-down Bundle | Son of sevenless (SoS) protein; Chain S, domain 1 | Son of sevenless (SoS) protein Chain: S domain 1 | ||
| Mainly Beta | Sandwich | Jelly Rolls | Jelly Rolls | ||
| Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
