3R8K | Genus

Total Genus 40

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	40
sequence length	180
structure length	180
Chain Sequence	AVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Apoptosis
source organism	Homo sapiens
publication title	Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL. pubmed doi rcsb
molecule keywords	Heme-binding protein 2
total genus	40
structure length	180
sequence length	180
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2011-03-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF04832	SOUL	SOUL heme-binding protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.20.80.10	Alpha Beta	Alpha-Beta Barrel	Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A	Regulatory factor, effector binding domain	3r8kA00

1D5YA 3Q5RA 1BOWA 1R8EA 3D6YA 1JYHA 2HVAA 1EXJA 3Q3DA 5KCBA 3GK6A 3B49A 3D71A 3Q5PA 3R8KA 5GQQA 3LURA 5KAUA 4A1MA 3R8JA 2GOVA 4AYZA 4B0YA 3Q2YA 5KAVA 4AYZB 3IAOA 5KATA 5KAWA 1EXIA 3Q5SA 5KAXA 2BOWA 2KCUA 3Q1MA 3D70A 3D6ZA 3E0HA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1D5Y A;  3Q5R A;  1BOW A;  1R8E A;  3D6Y A;  1JYH A;  2HVA A;  1EXJ A;  3Q3D A;  5KCB A;  3GK6 A;  3B49 A;  3D71 A;  3Q5P A;  3R8K A;  5GQQ A;  3LUR A;  5KAU A;  4A1M A;  3R8J A;  2GOV A;  4AYZ A;  4B0Y A;  3Q2Y A;  5KAV A;  4AYZ B;  3IAO A;  5KAT A;  5KAW A;  1EXI A;  3Q5S A;  5KAX A;  2BOW A;  2KCU A;  3Q1M A;  3D70 A;  3D6Z A;  3E0H A; 
#chains in the Genus database with same CATH topology
 1D5Y A;  3Q5R A;  1BOW A;  1R8E A;  3D6Y A;  1JYH A;  2HVA A;  1EXJ A;  3Q3D A;  5KCB A;  3GK6 A;  3B49 A;  3D71 A;  3Q5P A;  3R8K A;  5GQQ A;  3LUR A;  5KAU A;  4A1M A;  3R8J A;  2GOV A;  4AYZ A;  4B0Y A;  3Q2Y A;  5KAV A;  4AYZ B;  3IAO A;  5KAT A;  5KAW A;  1EXI A;  3Q5S A;  5KAX A;  2BOW A;  2KCU A;  3Q1M A;  3D70 A;  3D6Z A;  3E0H A; 
#chains in the Genus database with same CATH homology
 1D5Y A;  3Q5R A;  1BOW A;  1R8E A;  3D6Y A;  1JYH A;  2HVA A;  1EXJ A;  3Q3D A;  5KCB A;  3GK6 A;  3B49 A;  3D71 A;  3Q5P A;  3R8K A;  5GQQ A;  3LUR A;  5KAU A;  4A1M A;  3R8J A;  2GOV A;  4AYZ A;  4B0Y A;  3Q2Y A;  5KAV A;  4AYZ B;  3IAO A;  5KAT A;  5KAW A;  1EXI A;  3Q5S A;  5KAX A;  2BOW A;  2KCU A;  3Q1M A;  3D70 A;  3D6Z A;  3E0H A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3R8KA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations