3R8KA

Crystal structure of human soul protein (hexagonal form)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
180
structure length
180
Chain Sequence
AVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Apoptosis
source organism Homo sapiens
publication title Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.
pubmed doi rcsb
molecule keywords Heme-binding protein 2
total genus 40
structure length 180
sequence length 180
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04832 SOUL SOUL heme-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 3r8kA00
5GQQA 1JYHA 3R8KA 2KCUA 3Q5RA 3Q5SA 1BOWA 3D6YA 3GK6A 2BOWA 3E0HA 3R8JA 1EXIA 5KATA 2GOVA 1R8EA 3IAOA 3Q5PA 3D71A 4B0YA 4AYZA 3Q2YA 3LURA 5KAUA 3D70A 3Q1MA 2HVAA 1EXJA 4A1MA 1D5YA 5KAWA 5KAXA 5KCBA 3D6ZA 3B49A 3Q3DA 5KAVA 4AYZB
chains in the Genus database with same CATH superfamily
5GQQA 1JYHA 3R8KA 2KCUA 3Q5RA 3Q5SA 1BOWA 3D6YA 3GK6A 2BOWA 3E0HA 3R8JA 1EXIA 5KATA 2GOVA 1R8EA 3IAOA 3Q5PA 3D71A 4B0YA 4AYZA 3Q2YA 3LURA 5KAUA 3D70A 3Q1MA 2HVAA 1EXJA 4A1MA 1D5YA 5KAWA 5KAXA 5KCBA 3D6ZA 3B49A 3Q3DA 5KAVA 4AYZB
chains in the Genus database with same CATH topology
5GQQA 1JYHA 3R8KA 2KCUA 3Q5RA 3Q5SA 1BOWA 3D6YA 3GK6A 2BOWA 3E0HA 3R8JA 1EXIA 5KATA 2GOVA 1R8EA 3IAOA 3Q5PA 3D71A 4B0YA 4AYZA 3Q2YA 3LURA 5KAUA 3D70A 3Q1MA 2HVAA 1EXJA 4A1MA 1D5YA 5KAWA 5KAXA 5KCBA 3D6ZA 3B49A 3Q3DA 5KAVA 4AYZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GQQ A;  1JYH A;  3R8K A;  2KCU A;  3Q5R A;  3Q5S A;  1BOW A;  3D6Y A;  3GK6 A;  2BOW A;  3E0H A;  3R8J A;  1EXI A;  5KAT A;  2GOV A;  1R8E A;  3IAO A;  3Q5P A;  3D71 A;  4B0Y A;  4AYZ A;  3Q2Y A;  3LUR A;  5KAU A;  3D70 A;  3Q1M A;  2HVA A;  1EXJ A;  4A1M A;  1D5Y A;  5KAW A;  5KAX A;  5KCB A;  3D6Z A;  3B49 A;  3Q3D A;  5KAV A;  4AYZ B; 
#chains in the Genus database with same CATH topology
 5GQQ A;  1JYH A;  3R8K A;  2KCU A;  3Q5R A;  3Q5S A;  1BOW A;  3D6Y A;  3GK6 A;  2BOW A;  3E0H A;  3R8J A;  1EXI A;  5KAT A;  2GOV A;  1R8E A;  3IAO A;  3Q5P A;  3D71 A;  4B0Y A;  4AYZ A;  3Q2Y A;  3LUR A;  5KAU A;  3D70 A;  3Q1M A;  2HVA A;  1EXJ A;  4A1M A;  1D5Y A;  5KAW A;  5KAX A;  5KCB A;  3D6Z A;  3B49 A;  3Q3D A;  5KAV A;  4AYZ B; 
#chains in the Genus database with same CATH homology
 5GQQ A;  1JYH A;  3R8K A;  2KCU A;  3Q5R A;  3Q5S A;  1BOW A;  3D6Y A;  3GK6 A;  2BOW A;  3E0H A;  3R8J A;  1EXI A;  5KAT A;  2GOV A;  1R8E A;  3IAO A;  3Q5P A;  3D71 A;  4B0Y A;  4AYZ A;  3Q2Y A;  3LUR A;  5KAU A;  3D70 A;  3Q1M A;  2HVA A;  1EXJ A;  4A1M A;  1D5Y A;  5KAW A;  5KAX A;  5KCB A;  3D6Z A;  3B49 A;  3Q3D A;  5KAV A;  4AYZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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