3CLZA

The set and ring associated (sra) domain of uhrf1 bound to methylated dna
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
204
structure length
204
Chain Sequence
NHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase UHRF1
total genus 61
structure length 204
sequence length 204
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3clzA01
3CLZA 4PW7A 3DWHA 3F8JB 4PW5A 2ZKDA 2ZO0B 2ZO1B 2ZKFA 2ZO2B 4PW6A 2ZKEA 3FDEA 3F8IA 3BI7A 4NJ5A 2ZKGA 2PB7A 3OLNA
chains in the Genus database with same CATH superfamily
4RZLA 3CLZA 3Q0BX 4PW7A 3DWHA 3Q0FA 3F8JB 4PW5A 2ZKDA 2ZO0B 4F0QA 4R28A 2ZKFA 2ZO1B 3Q0CA 2ZO2B 4PW6A 3Q0DA 4YGIA 4F0PA 2ZKEA 3FDEA 4OC8A 3F8IA 3BI7A 4NJ5A 2ZKGA 2PB7A 3OLNA
chains in the Genus database with same CATH topology
3CLZA 4PW7A 3DWHA 3F8JB 4PW5A 2ZKDA 2ZO0B 2ZO1B 2ZKFA 2ZO2B 4PW6A 2ZKEA 3FDEA 3F8IA 3BI7A 4NJ5A 2ZKGA 2PB7A 3OLNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CLZ A;  4PW7 A;  3DWH A;  3F8J B;  4PW5 A;  2ZKD A;  2ZO0 B;  2ZO1 B;  2ZKF A;  2ZO2 B;  4PW6 A;  2ZKE A;  3FDE A;  3F8I A;  3BI7 A;  4NJ5 A;  2ZKG A;  2PB7 A;  3OLN A; 
#chains in the Genus database with same CATH topology
 4RZL A;  3CLZ A;  3Q0B X;  4PW7 A;  3DWH A;  3Q0F A;  3F8J B;  4PW5 A;  2ZKD A;  2ZO0 B;  4F0Q A;  4R28 A;  2ZKF A;  2ZO1 B;  3Q0C A;  2ZO2 B;  4PW6 A;  3Q0D A;  4YGI A;  4F0P A;  2ZKE A;  3FDE A;  4OC8 A;  3F8I A;  3BI7 A;  4NJ5 A;  2ZKG A;  2PB7 A;  3OLN A; 
#chains in the Genus database with same CATH homology
 3CLZ A;  4PW7 A;  3DWH A;  3F8J B;  4PW5 A;  2ZKD A;  2ZO0 B;  2ZO1 B;  2ZKF A;  2ZO2 B;  4PW6 A;  2ZKE A;  3FDE A;  3F8I A;  3BI7 A;  4NJ5 A;  2ZKG A;  2PB7 A;  3OLN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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