3F8IA

Mouse uhrf1 sra domain bound with hemi-methylated cpg, crystal structure in space group p21
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
206
structure length
206
Chain Sequence
HMPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
pubmed rcsb
molecule tags Ligase/dna
source organism Mus musculus
molecule keywords E3 ubiquitin-protein ligase UHRF1
total genus 57
structure length 206
sequence length 206
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3f8iA01
2ZKGA 3BI7A 2ZKEA 3F8IA 4PW7A 3FDEA 3F8JB 2ZO0B 4PW6A 2ZO1B 4NJ5A 3CLZA 3OLNA 4PW5A 2ZO2B 2ZKDA 2ZKFA 2PB7A 3DWHA
chains in the Genus database with same CATH superfamily
2ZKGA 4R28A 3BI7A 4F0PA 4YGIA 3Q0FA 2ZKEA 3F8IA 3Q0DA 4PW7A 3FDEA 3F8JB 3Q0CA 2ZO0B 3Q0BX 4PW6A 2ZO1B 4NJ5A 3CLZA 3OLNA 4RZLA 4PW5A 2ZO2B 2ZKDA 2PB7A 2ZKFA 4F0QA 4OC8A 3DWHA
chains in the Genus database with same CATH topology
2ZKGA 3BI7A 2ZKEA 3F8IA 4PW7A 3FDEA 3F8JB 2ZO0B 4PW6A 2ZO1B 4NJ5A 3CLZA 3OLNA 4PW5A 2ZO2B 2ZKDA 2ZKFA 2PB7A 3DWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKG A;  3BI7 A;  2ZKE A;  3F8I A;  4PW7 A;  3FDE A;  3F8J B;  2ZO0 B;  4PW6 A;  2ZO1 B;  4NJ5 A;  3CLZ A;  3OLN A;  4PW5 A;  2ZO2 B;  2ZKD A;  2ZKF A;  2PB7 A;  3DWH A; 
#chains in the Genus database with same CATH topology
 2ZKG A;  4R28 A;  3BI7 A;  4F0P A;  4YGI A;  3Q0F A;  2ZKE A;  3F8I A;  3Q0D A;  4PW7 A;  3FDE A;  3F8J B;  3Q0C A;  2ZO0 B;  3Q0B X;  4PW6 A;  2ZO1 B;  4NJ5 A;  3CLZ A;  3OLN A;  4RZL A;  4PW5 A;  2ZO2 B;  2ZKD A;  2PB7 A;  2ZKF A;  4F0Q A;  4OC8 A;  3DWH A; 
#chains in the Genus database with same CATH homology
 2ZKG A;  3BI7 A;  2ZKE A;  3F8I A;  4PW7 A;  3FDE A;  3F8J B;  2ZO0 B;  4PW6 A;  2ZO1 B;  4NJ5 A;  3CLZ A;  3OLN A;  4PW5 A;  2ZO2 B;  2ZKD A;  2ZKF A;  2PB7 A;  3DWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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