4PW6A

Structure of uhrf2-sra in complex with a 5hmc-containing dna, complex ii
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
202
structure length
188
Chain Sequence
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
pubmed doi rcsb
molecule keywords E3 ubiquitin-protein ligase UHRF2
molecule tags Ligase/dna
source organism Homo sapiens
total genus 56
structure length 188
sequence length 202
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2014-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 4pw6A01
2ZO1B 3OLNA 4PW7A 2ZKEA 2ZO0B 2ZKFA 2ZO2B 2ZKGA 3FDEA 3F8IA 3DWHA 3CLZA 4PW6A 2PB7A 3BI7A 4PW5A 2ZKDA 4NJ5A 3F8JB
chains in the Genus database with same CATH superfamily
2ZO1B 3Q0BX 4RZLA 3OLNA 3Q0DA 4PW7A 2ZKEA 2ZO0B 3Q0CA 4PW5A 2ZKFA 2ZO2B 4OC8A 3Q0FA 3FDEA 4F0QA 4YGIA 3F8IA 3DWHA 4R28A 3CLZA 4F0PA 4PW6A 2PB7A 3BI7A 2ZKGA 2ZKDA 4NJ5A 3F8JB
chains in the Genus database with same CATH topology
2ZO1B 3OLNA 4PW7A 2ZKEA 2ZO0B 2ZKFA 2ZO2B 2ZKGA 3FDEA 3F8IA 3DWHA 3CLZA 4PW6A 2PB7A 3BI7A 4PW5A 2ZKDA 4NJ5A 3F8JB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZO1 B;  3OLN A;  4PW7 A;  2ZKE A;  2ZO0 B;  2ZKF A;  2ZO2 B;  2ZKG A;  3FDE A;  3F8I A;  3DWH A;  3CLZ A;  4PW6 A;  2PB7 A;  3BI7 A;  4PW5 A;  2ZKD A;  4NJ5 A;  3F8J B; 
#chains in the Genus database with same CATH topology
 2ZO1 B;  3Q0B X;  4RZL A;  3OLN A;  3Q0D A;  4PW7 A;  2ZKE A;  2ZO0 B;  3Q0C A;  4PW5 A;  2ZKF A;  2ZO2 B;  4OC8 A;  3Q0F A;  3FDE A;  4F0Q A;  4YGI A;  3F8I A;  3DWH A;  4R28 A;  3CLZ A;  4F0P A;  4PW6 A;  2PB7 A;  3BI7 A;  2ZKG A;  2ZKD A;  4NJ5 A;  3F8J B; 
#chains in the Genus database with same CATH homology
 2ZO1 B;  3OLN A;  4PW7 A;  2ZKE A;  2ZO0 B;  2ZKF A;  2ZO2 B;  2ZKG A;  3FDE A;  3F8I A;  3DWH A;  3CLZ A;  4PW6 A;  2PB7 A;  3BI7 A;  4PW5 A;  2ZKD A;  4NJ5 A;  3F8J B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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