4PW7A

Structure of uhrf2-sra in complex with a 5mc-containing dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
202
structure length
197
Chain Sequence
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGGKKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
pubmed doi rcsb
molecule tags Ligase/dna
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase UHRF2
total genus 60
structure length 197
sequence length 202
chains with identical sequence B, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2014-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 4pw7A01
2ZKGA 3F8JB 4PW5A 3OLNA 4PW7A 3F8IA 4NJ5A 2ZO1B 2PB7A 3FDEA 3BI7A 4PW6A 3CLZA 2ZKFA 2ZKDA 3DWHA 2ZO0B 2ZO2B 2ZKEA
chains in the Genus database with same CATH superfamily
4OC8A 4RZLA 2ZKGA 3Q0DA 3F8JB 4YGIA 4PW5A 3OLNA 4PW7A 4F0QA 3F8IA 4NJ5A 2ZO1B 2PB7A 3FDEA 3BI7A 4R28A 3Q0BX 4PW6A 3CLZA 2ZKFA 3Q0FA 3Q0CA 2ZKDA 3DWHA 4F0PA 2ZO0B 2ZO2B 2ZKEA
chains in the Genus database with same CATH topology
2ZKGA 3F8JB 4PW5A 3OLNA 4PW7A 3F8IA 4NJ5A 2ZO1B 2PB7A 3FDEA 3BI7A 4PW6A 3CLZA 2ZKFA 2ZKDA 3DWHA 2ZO0B 2ZO2B 2ZKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKG A;  3F8J B;  4PW5 A;  3OLN A;  4PW7 A;  3F8I A;  4NJ5 A;  2ZO1 B;  2PB7 A;  3FDE A;  3BI7 A;  4PW6 A;  3CLZ A;  2ZKF A;  2ZKD A;  3DWH A;  2ZO0 B;  2ZO2 B;  2ZKE A; 
#chains in the Genus database with same CATH topology
 4OC8 A;  4RZL A;  2ZKG A;  3Q0D A;  3F8J B;  4YGI A;  4PW5 A;  3OLN A;  4PW7 A;  4F0Q A;  3F8I A;  4NJ5 A;  2ZO1 B;  2PB7 A;  3FDE A;  3BI7 A;  4R28 A;  3Q0B X;  4PW6 A;  3CLZ A;  2ZKF A;  3Q0F A;  3Q0C A;  2ZKD A;  3DWH A;  4F0P A;  2ZO0 B;  2ZO2 B;  2ZKE A; 
#chains in the Genus database with same CATH homology
 2ZKG A;  3F8J B;  4PW5 A;  3OLN A;  4PW7 A;  3F8I A;  4NJ5 A;  2ZO1 B;  2PB7 A;  3FDE A;  3BI7 A;  4PW6 A;  3CLZ A;  2ZKF A;  2ZKD A;  3DWH A;  2ZO0 B;  2ZO2 B;  2ZKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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