4PW5A

Structure of uhrf2-sra in complex with a 5hmc-containing dna, complex i
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
201
structure length
189
Chain Sequence
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGGSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
pubmed doi rcsb
molecule tags Ligase/dna
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase UHRF2
total genus 59
structure length 189
sequence length 201
chains with identical sequence B, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2014-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 4pw5A01
4PW6A 2ZO2B 3CLZA 3F8JB 4PW7A 2ZKGA 2ZKEA 3F8IA 2ZO0B 2ZKFA 2ZO1B 3DWHA 3BI7A 3OLNA 4NJ5A 2PB7A 3FDEA 2ZKDA 4PW5A
chains in the Genus database with same CATH superfamily
4F0PA 4PW6A 2ZO2B 3Q0BX 3Q0CA 3F8JB 3CLZA 4PW7A 4R28A 4RZLA 2ZKGA 2ZKEA 3F8IA 2ZO0B 4YGIA 2ZKFA 2ZO1B 3DWHA 3BI7A 4OC8A 3OLNA 4NJ5A 2PB7A 4F0QA 3Q0DA 3Q0FA 3FDEA 2ZKDA 4PW5A
chains in the Genus database with same CATH topology
4PW6A 2ZO2B 3CLZA 3F8JB 4PW7A 2ZKGA 2ZKEA 3F8IA 2ZO0B 2ZKFA 2ZO1B 3DWHA 3BI7A 3OLNA 4NJ5A 2PB7A 3FDEA 2ZKDA 4PW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PW6 A;  2ZO2 B;  3CLZ A;  3F8J B;  4PW7 A;  2ZKG A;  2ZKE A;  3F8I A;  2ZO0 B;  2ZKF A;  2ZO1 B;  3DWH A;  3BI7 A;  3OLN A;  4NJ5 A;  2PB7 A;  3FDE A;  2ZKD A;  4PW5 A; 
#chains in the Genus database with same CATH topology
 4F0P A;  4PW6 A;  2ZO2 B;  3Q0B X;  3Q0C A;  3F8J B;  3CLZ A;  4PW7 A;  4R28 A;  4RZL A;  2ZKG A;  2ZKE A;  3F8I A;  2ZO0 B;  4YGI A;  2ZKF A;  2ZO1 B;  3DWH A;  3BI7 A;  4OC8 A;  3OLN A;  4NJ5 A;  2PB7 A;  4F0Q A;  3Q0D A;  3Q0F A;  3FDE A;  2ZKD A;  4PW5 A; 
#chains in the Genus database with same CATH homology
 4PW6 A;  2ZO2 B;  3CLZ A;  3F8J B;  4PW7 A;  2ZKG A;  2ZKE A;  3F8I A;  2ZO0 B;  2ZKF A;  2ZO1 B;  3DWH A;  3BI7 A;  3OLN A;  4NJ5 A;  2PB7 A;  3FDE A;  2ZKD A;  4PW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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