5KCBA

The structure of sav2435 bound to ethidium bromide
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
165
structure length
165
Chain Sequence
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIAKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQANTVKSAPFFELYQDGDTTSEKYITEIWMPVKGLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
pubmed doi rcsb
molecule tags Unknown function
source organism Staphylococcus aureus (strain n315)
molecule keywords SA2223 protein
total genus 40
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2016-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 5kcbA00
3LURA 2HVAA 3R8JA 3Q5PA 3Q3DA 3D71A 3IAOA 3D6ZA 3E0HA 1JYHA 4AYZB 5GQQA 4A1MA 3D6YA 3D70A 5KATA 5KCBA 4AYZA 3Q1MA 1EXIA 4B0YA 5KAVA 3Q2YA 3R8KA 2GOVA 3B49A 2KCUA 5KAXA 1BOWA 1EXJA 5KAWA 3Q5RA 3GK6A 2BOWA 1R8EA 1D5YA 5KAUA 3Q5SA
chains in the Genus database with same CATH superfamily
3LURA 2HVAA 3R8JA 3Q5PA 3Q3DA 3D71A 3IAOA 3D6ZA 3E0HA 1JYHA 4AYZB 5GQQA 4A1MA 3D6YA 3D70A 5KATA 5KCBA 4AYZA 3Q1MA 1EXIA 4B0YA 5KAVA 3Q2YA 3R8KA 2GOVA 3B49A 2KCUA 5KAXA 1BOWA 1EXJA 5KAWA 3Q5RA 3GK6A 2BOWA 1R8EA 1D5YA 5KAUA 3Q5SA
chains in the Genus database with same CATH topology
3LURA 2HVAA 3R8JA 3Q5PA 3Q3DA 3D71A 3IAOA 3D6ZA 3E0HA 1JYHA 4AYZB 5GQQA 4A1MA 3D6YA 3D70A 5KATA 5KCBA 4AYZA 3Q1MA 1EXIA 4B0YA 5KAVA 3Q2YA 3R8KA 2GOVA 3B49A 2KCUA 5KAXA 1BOWA 1EXJA 5KAWA 3Q5RA 3GK6A 2BOWA 1R8EA 1D5YA 5KAUA 3Q5SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LUR A;  2HVA A;  3R8J A;  3Q5P A;  3Q3D A;  3D71 A;  3IAO A;  3D6Z A;  3E0H A;  1JYH A;  4AYZ B;  5GQQ A;  4A1M A;  3D6Y A;  3D70 A;  5KAT A;  5KCB A;  4AYZ A;  3Q1M A;  1EXI A;  4B0Y A;  5KAV A;  3Q2Y A;  3R8K A;  2GOV A;  3B49 A;  2KCU A;  5KAX A;  1BOW A;  1EXJ A;  5KAW A;  3Q5R A;  3GK6 A;  2BOW A;  1R8E A;  1D5Y A;  5KAU A;  3Q5S A; 
#chains in the Genus database with same CATH topology
 3LUR A;  2HVA A;  3R8J A;  3Q5P A;  3Q3D A;  3D71 A;  3IAO A;  3D6Z A;  3E0H A;  1JYH A;  4AYZ B;  5GQQ A;  4A1M A;  3D6Y A;  3D70 A;  5KAT A;  5KCB A;  4AYZ A;  3Q1M A;  1EXI A;  4B0Y A;  5KAV A;  3Q2Y A;  3R8K A;  2GOV A;  3B49 A;  2KCU A;  5KAX A;  1BOW A;  1EXJ A;  5KAW A;  3Q5R A;  3GK6 A;  2BOW A;  1R8E A;  1D5Y A;  5KAU A;  3Q5S A; 
#chains in the Genus database with same CATH homology
 3LUR A;  2HVA A;  3R8J A;  3Q5P A;  3Q3D A;  3D71 A;  3IAO A;  3D6Z A;  3E0H A;  1JYH A;  4AYZ B;  5GQQ A;  4A1M A;  3D6Y A;  3D70 A;  5KAT A;  5KCB A;  4AYZ A;  3Q1M A;  1EXI A;  4B0Y A;  5KAV A;  3Q2Y A;  3R8K A;  2GOV A;  3B49 A;  2KCU A;  5KAX A;  1BOW A;  1EXJ A;  5KAW A;  3Q5R A;  3GK6 A;  2BOW A;  1R8E A;  1D5Y A;  5KAU A;  3Q5S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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