5L3LA

D11 bound igf-ii
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Insulin-like growth factor II
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3lA00
1EFEA 1IMXA 1TGRA 3LRIA 6INSE 2KJIA 1BQTA 2DSRI 1WQJI 4XSSB 1H02B 2LWZA 1GZRB 2KQPA 1GZYB 1ZEIA 2GF1A 2DSQC 2JZQA 1PMXA 1IGLA 2DSPI 5L3LA 1GZZB 5L3NA 2L29B 1B9GA 3KR3D 3GF1A 1SJUA 1H59A 5L3MA
chains in the Genus database with same CATH superfamily
1EFEA 1IMXA 1TGRA 3LRIA 6INSE 2KJIA 1BQTA 2DSRI 1WQJI 4XSSB 1H02B 2LWZA 1GZRB 2KQPA 1GZYB 1ZEIA 2GF1A 2DSQC 2JZQA 1PMXA 1IGLA 2DSPI 5L3LA 3F2DA 1GZZB 5L3NA 2L29B 1B9GA 3F2CA 3KR3D 3GF1A 3F2BA 1SJUA 2L14B 1H59A 5L3MA
chains in the Genus database with same CATH topology
1EFEA 1IMXA 1TGRA 3LRIA 6INSE 2KJIA 1BQTA 2DSRI 1WQJI 4XSSB 1H02B 2LWZA 1GZRB 2KQPA 1GZYB 1ZEIA 2GF1A 2DSQC 2JZQA 1PMXA 1IGLA 2DSPI 5L3LA 1GZZB 5L3NA 2L29B 1B9GA 3KR3D 3GF1A 1SJUA 1H59A 5L3MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EFE A;  1IMX A;  1TGR A;  3LRI A;  6INS E;  2KJI A;  1BQT A;  2DSR I;  1WQJ I;  4XSS B;  1H02 B;  2LWZ A;  1GZR B;  2KQP A;  1GZY B;  1ZEI A;  2GF1 A;  2DSQ C;  2JZQ A;  1PMX A;  1IGL A;  2DSP I;  5L3L A;  1GZZ B;  5L3N A;  2L29 B;  1B9G A;  3KR3 D;  3GF1 A;  1SJU A;  1H59 A;  5L3M A; 
#chains in the Genus database with same CATH topology
 1EFE A;  1IMX A;  1TGR A;  3LRI A;  6INS E;  2KJI A;  1BQT A;  2DSR I;  1WQJ I;  4XSS B;  1H02 B;  2LWZ A;  1GZR B;  2KQP A;  1GZY B;  1ZEI A;  2GF1 A;  2DSQ C;  2JZQ A;  1PMX A;  1IGL A;  2DSP I;  5L3L A;  3F2D A;  1GZZ B;  5L3N A;  2L29 B;  1B9G A;  3F2C A;  3KR3 D;  3GF1 A;  3F2B A;  1SJU A;  2L14 B;  1H59 A;  5L3M A; 
#chains in the Genus database with same CATH homology
 1EFE A;  1IMX A;  1TGR A;  3LRI A;  6INS E;  2KJI A;  1BQT A;  2DSR I;  1WQJ I;  4XSS B;  1H02 B;  2LWZ A;  1GZR B;  2KQP A;  1GZY B;  1ZEI A;  2GF1 A;  2DSQ C;  2JZQ A;  1PMX A;  1IGL A;  2DSP I;  5L3L A;  1GZZ B;  5L3N A;  2L29 B;  1B9G A;  3KR3 D;  3GF1 A;  1SJU A;  1H59 A;  5L3M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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