5L3LA

D11 bound igf-ii
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
molecule keywords Insulin-like growth factor II
molecule tags Cell cycle
source organism Homo sapiens
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3lA00
2L29B 3KR3D 1GZYB 1TGRA 2DSRI 1BQTA 2KJIA 5L3NA 1H02B 3GF1A 1IMXA 1GZZB 2KQPA 6INSE 2DSPI 1ZEIA 1B9GA 2GF1A 4XSSB 1SJUA 2JZQA 3LRIA 1H59A 1PMXA 1WQJI 1GZRB 2LWZA 5L3MA 2DSQC 1IGLA 5L3LA 1EFEA
chains in the Genus database with same CATH superfamily
2L29B 3KR3D 1GZYB 1TGRA 2DSRI 1BQTA 2KJIA 5L3NA 1H02B 2L14B 3GF1A 1IMXA 1GZZB 2KQPA 6INSE 2DSPI 1ZEIA 3F2DA 3F2CA 1B9GA 2GF1A 4XSSB 1SJUA 2JZQA 3LRIA 1H59A 3F2BA 1PMXA 1WQJI 1GZRB 2LWZA 5L3MA 2DSQC 1IGLA 5L3LA 1EFEA
chains in the Genus database with same CATH topology
2L29B 3KR3D 1GZYB 1TGRA 2DSRI 1BQTA 2KJIA 5L3NA 1H02B 3GF1A 1IMXA 1GZZB 2KQPA 6INSE 2DSPI 1ZEIA 1B9GA 2GF1A 4XSSB 1SJUA 2JZQA 3LRIA 1H59A 1PMXA 1WQJI 1GZRB 2LWZA 5L3MA 2DSQC 1IGLA 5L3LA 1EFEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L29 B;  3KR3 D;  1GZY B;  1TGR A;  2DSR I;  1BQT A;  2KJI A;  5L3N A;  1H02 B;  3GF1 A;  1IMX A;  1GZZ B;  2KQP A;  6INS E;  2DSP I;  1ZEI A;  1B9G A;  2GF1 A;  4XSS B;  1SJU A;  2JZQ A;  3LRI A;  1H59 A;  1PMX A;  1WQJ I;  1GZR B;  2LWZ A;  5L3M A;  2DSQ C;  1IGL A;  5L3L A;  1EFE A; 
#chains in the Genus database with same CATH topology
 2L29 B;  3KR3 D;  1GZY B;  1TGR A;  2DSR I;  1BQT A;  2KJI A;  5L3N A;  1H02 B;  2L14 B;  3GF1 A;  1IMX A;  1GZZ B;  2KQP A;  6INS E;  2DSP I;  1ZEI A;  3F2D A;  3F2C A;  1B9G A;  2GF1 A;  4XSS B;  1SJU A;  2JZQ A;  3LRI A;  1H59 A;  3F2B A;  1PMX A;  1WQJ I;  1GZR B;  2LWZ A;  5L3M A;  2DSQ C;  1IGL A;  5L3L A;  1EFE A; 
#chains in the Genus database with same CATH homology
 2L29 B;  3KR3 D;  1GZY B;  1TGR A;  2DSR I;  1BQT A;  2KJI A;  5L3N A;  1H02 B;  3GF1 A;  1IMX A;  1GZZ B;  2KQP A;  6INS E;  2DSP I;  1ZEI A;  1B9G A;  2GF1 A;  4XSS B;  1SJU A;  2JZQ A;  3LRI A;  1H59 A;  1PMX A;  1WQJ I;  1GZR B;  2LWZ A;  5L3M A;  2DSQ C;  1IGL A;  5L3L A;  1EFE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...