5L3MA

D11 bound [s39_pq]-igf-ii
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
69
structure length
69
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSPQRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Insulin-like growth factor II
total genus 18
structure length 69
sequence length 69
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3mA00
1IMXA 6INSE 1GZRB 1GZYB 1ZEIA 1WQJI 2GF1A 2LWZA 3LRIA 5L3NA 1PMXA 1GZZB 1B9GA 5L3MA 1BQTA 2L29B 1IGLA 2JZQA 1H59A 3KR3D 4XSSB 2DSRI 1TGRA 2KJIA 1EFEA 1SJUA 1H02B 5L3LA 3GF1A 2DSPI 2KQPA 2DSQC
chains in the Genus database with same CATH superfamily
1IMXA 6INSE 1GZRB 1GZYB 1ZEIA 1WQJI 2GF1A 2LWZA 3LRIA 5L3NA 1PMXA 1GZZB 1B9GA 5L3MA 1BQTA 2L29B 3F2CA 1IGLA 2JZQA 1H59A 3KR3D 4XSSB 2DSRI 1TGRA 2KJIA 1EFEA 3F2BA 1SJUA 3F2DA 1H02B 5L3LA 3GF1A 2DSPI 2KQPA 2L14B 2DSQC
chains in the Genus database with same CATH topology
1IMXA 6INSE 1GZRB 1GZYB 1ZEIA 1WQJI 2GF1A 2LWZA 3LRIA 5L3NA 1PMXA 1GZZB 1B9GA 5L3MA 1BQTA 2L29B 1IGLA 2JZQA 1H59A 3KR3D 4XSSB 2DSRI 1TGRA 2KJIA 1EFEA 1SJUA 1H02B 5L3LA 3GF1A 2DSPI 2KQPA 2DSQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IMX A;  6INS E;  1GZR B;  1GZY B;  1ZEI A;  1WQJ I;  2GF1 A;  2LWZ A;  3LRI A;  5L3N A;  1PMX A;  1GZZ B;  1B9G A;  5L3M A;  1BQT A;  2L29 B;  1IGL A;  2JZQ A;  1H59 A;  3KR3 D;  4XSS B;  2DSR I;  1TGR A;  2KJI A;  1EFE A;  1SJU A;  1H02 B;  5L3L A;  3GF1 A;  2DSP I;  2KQP A;  2DSQ C; 
#chains in the Genus database with same CATH topology
 1IMX A;  6INS E;  1GZR B;  1GZY B;  1ZEI A;  1WQJ I;  2GF1 A;  2LWZ A;  3LRI A;  5L3N A;  1PMX A;  1GZZ B;  1B9G A;  5L3M A;  1BQT A;  2L29 B;  3F2C A;  1IGL A;  2JZQ A;  1H59 A;  3KR3 D;  4XSS B;  2DSR I;  1TGR A;  2KJI A;  1EFE A;  3F2B A;  1SJU A;  3F2D A;  1H02 B;  5L3L A;  3GF1 A;  2DSP I;  2KQP A;  2L14 B;  2DSQ C; 
#chains in the Genus database with same CATH homology
 1IMX A;  6INS E;  1GZR B;  1GZY B;  1ZEI A;  1WQJ I;  2GF1 A;  2LWZ A;  3LRI A;  5L3N A;  1PMX A;  1GZZ B;  1B9G A;  5L3M A;  1BQT A;  2L29 B;  1IGL A;  2JZQ A;  1H59 A;  3KR3 D;  4XSS B;  2DSR I;  1TGR A;  2KJI A;  1EFE A;  1SJU A;  1H02 B;  5L3L A;  3GF1 A;  2DSP I;  2KQP A;  2DSQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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