6INSE

X-ray analysis of the single chain b29-a1 peptide-linked insulin molecule. a completely inactive analogue
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
50
structure length
50
Chain Sequence
FVNQHLCGSHLVEALYLVCGERGFFYTPKGIVEQCCTSICSLYQLENYCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
pubmed doi rcsb
molecule keywords INSULIN
molecule tags Hormone
source organism Sus scrofa
total genus 3
structure length 50
sequence length 50
chains with identical sequence F
ec nomenclature
pdb deposition date 1992-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 6insE00
2KQPA 1ZEIA 2DSRI 3LRIA 2L29B 2DSPI 1GZZB 1TGRA 1H59A 1IMXA 3GF1A 1EFEA 1GZYB 1GZRB 2JZQA 5L3NA 2GF1A 1SJUA 1B9GA 5L3MA 1PMXA 1IGLA 1H02B 2KJIA 2DSQC 4XSSB 1WQJI 6INSE 2LWZA 5L3LA 1BQTA 3KR3D
chains in the Genus database with same CATH superfamily
2KQPA 1ZEIA 2DSRI 3LRIA 2L29B 2DSPI 1GZZB 1TGRA 1H59A 3F2DA 1IMXA 3GF1A 1EFEA 1GZYB 1GZRB 2JZQA 2L14B 5L3NA 2GF1A 1SJUA 1B9GA 5L3MA 1PMXA 1IGLA 1H02B 2KJIA 3F2BA 2DSQC 4XSSB 1WQJI 6INSE 2LWZA 5L3LA 1BQTA 3F2CA 3KR3D
chains in the Genus database with same CATH topology
2KQPA 1ZEIA 2DSRI 3LRIA 2L29B 2DSPI 1GZZB 1TGRA 1H59A 1IMXA 3GF1A 1EFEA 1GZYB 1GZRB 2JZQA 5L3NA 2GF1A 1SJUA 1B9GA 5L3MA 1PMXA 1IGLA 1H02B 2KJIA 2DSQC 4XSSB 1WQJI 6INSE 2LWZA 5L3LA 1BQTA 3KR3D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KQP A;  1ZEI A;  2DSR I;  3LRI A;  2L29 B;  2DSP I;  1GZZ B;  1TGR A;  1H59 A;  1IMX A;  3GF1 A;  1EFE A;  1GZY B;  1GZR B;  2JZQ A;  5L3N A;  2GF1 A;  1SJU A;  1B9G A;  5L3M A;  1PMX A;  1IGL A;  1H02 B;  2KJI A;  2DSQ C;  4XSS B;  1WQJ I;  6INS E;  2LWZ A;  5L3L A;  1BQT A;  3KR3 D; 
#chains in the Genus database with same CATH topology
 2KQP A;  1ZEI A;  2DSR I;  3LRI A;  2L29 B;  2DSP I;  1GZZ B;  1TGR A;  1H59 A;  3F2D A;  1IMX A;  3GF1 A;  1EFE A;  1GZY B;  1GZR B;  2JZQ A;  2L14 B;  5L3N A;  2GF1 A;  1SJU A;  1B9G A;  5L3M A;  1PMX A;  1IGL A;  1H02 B;  2KJI A;  3F2B A;  2DSQ C;  4XSS B;  1WQJ I;  6INS E;  2LWZ A;  5L3L A;  1BQT A;  3F2C A;  3KR3 D; 
#chains in the Genus database with same CATH homology
 2KQP A;  1ZEI A;  2DSR I;  3LRI A;  2L29 B;  2DSP I;  1GZZ B;  1TGR A;  1H59 A;  1IMX A;  3GF1 A;  1EFE A;  1GZY B;  1GZR B;  2JZQ A;  5L3N A;  2GF1 A;  1SJU A;  1B9G A;  5L3M A;  1PMX A;  1IGL A;  1H02 B;  2KJI A;  2DSQ C;  4XSS B;  1WQJ I;  6INS E;  2LWZ A;  5L3L A;  1BQT A;  3KR3 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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