1AGRE

Complex of alf4-activated gi-alpha-1 with rgs4
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
128
structure length
128
Chain Sequence
VSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
pubmed doi rcsb
molecule tags Complex (signal transduction/regulator)
source organism Rattus norvegicus
molecule keywords GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)
total genus 50
structure length 128
sequence length 128
chains with identical sequence H
ec nomenclature
pdb deposition date 1997-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1agrE02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1agrE01
4MK0A 2V4ZB 3C7LA 3CIKA 1EZTA 5HE2A 3KRXA 3V5WA 2JNUA 3PSCA 2AF0A 2JM5A 1FQKB 1EMUA 2DLVA 2OJ4A 1EZYA 5DO9B 2D9JA 1FQIA 3C7KB 2IHBB 5HE1A 4EKDB 3KRWA 5HE0A 2IK8B 4TNBA 1OMWA 3NYOA 1CMZA 2OWIA 5HE3A 1AGRE 3UZTA 2CRPA 2BV1A 1FQJB 2ODEB 2EBZA 2BCJA 4PNKA 3PVWA 2BT2A 2GTPC 3NYNA 2IHDA 4TNDA 3PVUA 1DK8A
chains in the Genus database with same CATH superfamily
4MK0A 2V4ZB 3C7LA 3CIKA 1EZTA 5HE2A 3KRXA 3V5WA 2JNUA 3PSCA 2AF0A 2JM5A 1FQKB 1EMUA 2DLVA 2OJ4A 1EZYA 5DO9B 2D9JA 1FQIA 3C7KB 2IHBB 3I5QA 5HE1A 4EKDB 3KRWA 5HE0A 4HTEA 2IK8B 3QYFA 4TNBA 1OMWA 3NYOA 1CMZA 2OWIA 5HE3A 1AGRE 3UZTA 2CRPA 5REQB 2BV1A 1FQJB 2ODEB 2EBZA 2BCJA 4PNKA 3PVWA 2BT2A 2GTPC 3NYNA 2IHDA 4TNDA 3PVUA 1DK8A
chains in the Genus database with same CATH topology
4MK0A 2V4ZB 3C7LA 3CIKA 1EZTA 5HE2A 3KRXA 3V5WA 2JNUA 3PSCA 2AF0A 2JM5A 1FQKB 1EMUA 2DLVA 2OJ4A 1EZYA 5DO9B 2D9JA 1FQIA 3C7KB 2IHBB 5HE1A 4EKDB 3KRWA 5HE0A 2IK8B 3QYFA 4TNBA 1OMWA 3NYOA 1CMZA 2OWIA 5HE3A 1AGRE 3UZTA 2CRPA 5REQB 2BV1A 1FQJB 2ODEB 2EBZA 2BCJA 4PNKA 3PVWA 2BT2A 2GTPC 3NYNA 2IHDA 4TNDA 3PVUA 1DK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MK0 A;  2V4Z B;  3C7L A;  3CIK A;  1EZT A;  5HE2 A;  3KRX A;  3V5W A;  2JNU A;  3PSC A;  2AF0 A;  2JM5 A;  1FQK B;  1EMU A;  2DLV A;  2OJ4 A;  1EZY A;  5DO9 B;  2D9J A;  1FQI A;  3C7K B;  2IHB B;  5HE1 A;  4EKD B;  3KRW A;  5HE0 A;  2IK8 B;  4TNB A;  1OMW A;  3NYO A;  1CMZ A;  2OWI A;  5HE3 A;  1AGR E;  3UZT A;  2CRP A;  2BV1 A;  1FQJ B;  2ODE B;  2EBZ A;  2BCJ A;  4PNK A;  3PVW A;  2BT2 A;  2GTP C;  3NYN A;  2IHD A;  4TND A;  3PVU A;  1DK8 A; 
#chains in the Genus database with same CATH topology
 4MK0 A;  2V4Z B;  3C7L A;  3CIK A;  1EZT A;  5HE2 A;  3KRX A;  3V5W A;  2JNU A;  3PSC A;  2AF0 A;  2JM5 A;  1FQK B;  1EMU A;  2DLV A;  2OJ4 A;  1EZY A;  5DO9 B;  2D9J A;  1FQI A;  3C7K B;  2IHB B;  3I5Q A;  5HE1 A;  4EKD B;  3KRW A;  5HE0 A;  4HTE A;  2IK8 B;  3QYF A;  4TNB A;  1OMW A;  3NYO A;  1CMZ A;  2OWI A;  5HE3 A;  1AGR E;  3UZT A;  2CRP A;  5REQ B;  2BV1 A;  1FQJ B;  2ODE B;  2EBZ A;  2BCJ A;  4PNK A;  3PVW A;  2BT2 A;  2GTP C;  3NYN A;  2IHD A;  4TND A;  3PVU A;  1DK8 A; 
#chains in the Genus database with same CATH homology
 4MK0 A;  2V4Z B;  3C7L A;  3CIK A;  1EZT A;  5HE2 A;  3KRX A;  3V5W A;  2JNU A;  3PSC A;  2AF0 A;  2JM5 A;  1FQK B;  1EMU A;  2DLV A;  2OJ4 A;  1EZY A;  5DO9 B;  2D9J A;  1FQI A;  3C7K B;  2IHB B;  5HE1 A;  4EKD B;  3KRW A;  5HE0 A;  2IK8 B;  3QYF A;  4TNB A;  1OMW A;  3NYO A;  1CMZ A;  2OWI A;  5HE3 A;  1AGR E;  3UZT A;  2CRP A;  5REQ B;  2BV1 A;  1FQJ B;  2ODE B;  2EBZ A;  2BCJ A;  4PNK A;  3PVW A;  2BT2 A;  2GTP C;  3NYN A;  2IHD A;  4TND A;  3PVU A;  1DK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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