1AGRE

Complex of alf4-activated gi-alpha-1 with rgs4
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
128
structure length
128
Chain Sequence
VSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
pubmed doi rcsb
molecule keywords GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)
molecule tags Complex (signal transduction/regulator)
source organism Rattus norvegicus
total genus 50
structure length 128
sequence length 128
chains with identical sequence H
ec nomenclature
pdb deposition date 1997-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1agrE02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1agrE01
4TNDA 2JM5A 2BT2A 5HE3A 1EZTA 3PVWA 2OJ4A 1EMUA 4PNKA 4EKDB 1OMWA 3C7KB 3KRXA 3UZTA 4TNBA 5HE0A 1FQJB 3NYOA 2IHDA 1FQKB 1AGRE 2AF0A 2V4ZB 2OWIA 2D9JA 3KRWA 3C7LA 3PSCA 2JNUA 5HE2A 3V5WA 2GTPC 3PVUA 1EZYA 2EBZA 5HE1A 2IK8B 2CRPA 2DLVA 3NYNA 2BCJA 2BV1A 1DK8A 1CMZA 2IHBB 2ODEB 5DO9B 3CIKA 1FQIA 4MK0A
chains in the Genus database with same CATH superfamily
4TNDA 2JM5A 2BT2A 5HE3A 1EZTA 3PVWA 2OJ4A 1EMUA 4PNKA 4EKDB 1OMWA 3C7KB 3KRXA 3UZTA 5REQB 4TNBA 5HE0A 1FQJB 3NYOA 2IHDA 1FQKB 1AGRE 2AF0A 2V4ZB 2OWIA 2D9JA 3KRWA 3C7LA 3PSCA 2JNUA 5HE2A 3V5WA 2GTPC 3PVUA 1EZYA 2EBZA 5HE1A 2IK8B 2CRPA 2DLVA 3NYNA 4HTEA 3I5QA 2BCJA 2BV1A 1DK8A 1CMZA 2IHBB 2ODEB 3QYFA 5DO9B 3CIKA 1FQIA 4MK0A
chains in the Genus database with same CATH topology
4TNDA 2JM5A 2BT2A 5HE3A 1EZTA 3PVWA 2OJ4A 1EMUA 4PNKA 4EKDB 1OMWA 3C7KB 3KRXA 3UZTA 5REQB 4TNBA 5HE0A 1FQJB 3NYOA 2IHDA 1FQKB 1AGRE 2AF0A 2V4ZB 2OWIA 2D9JA 3KRWA 3C7LA 3PSCA 2JNUA 5HE2A 3V5WA 2GTPC 3PVUA 1EZYA 2EBZA 5HE1A 2IK8B 2CRPA 2DLVA 3NYNA 2BCJA 2BV1A 1DK8A 1CMZA 2IHBB 2ODEB 3QYFA 5DO9B 3CIKA 1FQIA 4MK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TND A;  2JM5 A;  2BT2 A;  5HE3 A;  1EZT A;  3PVW A;  2OJ4 A;  1EMU A;  4PNK A;  4EKD B;  1OMW A;  3C7K B;  3KRX A;  3UZT A;  4TNB A;  5HE0 A;  1FQJ B;  3NYO A;  2IHD A;  1FQK B;  1AGR E;  2AF0 A;  2V4Z B;  2OWI A;  2D9J A;  3KRW A;  3C7L A;  3PSC A;  2JNU A;  5HE2 A;  3V5W A;  2GTP C;  3PVU A;  1EZY A;  2EBZ A;  5HE1 A;  2IK8 B;  2CRP A;  2DLV A;  3NYN A;  2BCJ A;  2BV1 A;  1DK8 A;  1CMZ A;  2IHB B;  2ODE B;  5DO9 B;  3CIK A;  1FQI A;  4MK0 A; 
#chains in the Genus database with same CATH topology
 4TND A;  2JM5 A;  2BT2 A;  5HE3 A;  1EZT A;  3PVW A;  2OJ4 A;  1EMU A;  4PNK A;  4EKD B;  1OMW A;  3C7K B;  3KRX A;  3UZT A;  5REQ B;  4TNB A;  5HE0 A;  1FQJ B;  3NYO A;  2IHD A;  1FQK B;  1AGR E;  2AF0 A;  2V4Z B;  2OWI A;  2D9J A;  3KRW A;  3C7L A;  3PSC A;  2JNU A;  5HE2 A;  3V5W A;  2GTP C;  3PVU A;  1EZY A;  2EBZ A;  5HE1 A;  2IK8 B;  2CRP A;  2DLV A;  3NYN A;  4HTE A;  3I5Q A;  2BCJ A;  2BV1 A;  1DK8 A;  1CMZ A;  2IHB B;  2ODE B;  3QYF A;  5DO9 B;  3CIK A;  1FQI A;  4MK0 A; 
#chains in the Genus database with same CATH homology
 4TND A;  2JM5 A;  2BT2 A;  5HE3 A;  1EZT A;  3PVW A;  2OJ4 A;  1EMU A;  4PNK A;  4EKD B;  1OMW A;  3C7K B;  3KRX A;  3UZT A;  5REQ B;  4TNB A;  5HE0 A;  1FQJ B;  3NYO A;  2IHD A;  1FQK B;  1AGR E;  2AF0 A;  2V4Z B;  2OWI A;  2D9J A;  3KRW A;  3C7L A;  3PSC A;  2JNU A;  5HE2 A;  3V5W A;  2GTP C;  3PVU A;  1EZY A;  2EBZ A;  5HE1 A;  2IK8 B;  2CRP A;  2DLV A;  3NYN A;  2BCJ A;  2BV1 A;  1DK8 A;  1CMZ A;  2IHB B;  2ODE B;  3QYF A;  5DO9 B;  3CIK A;  1FQI A;  4MK0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...