2DLVA

Solution structure of the rgs domain of human regulator of g-protein signaling 18
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
140
structure length
140
Chain Sequence
GSSGSSGSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 18
publication title Solution structure of the RGS domain of human regulator of G-protein signaling 18
rcsb
source organism Homo sapiens
total genus 34
structure length 140
sequence length 140
ec nomenclature
pdb deposition date 2006-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2dlvA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2dlvA01
4PNKA 1FQJB 2AF0A 5HE0A 4EKDB 2CRPA 3PSCA 1OMWA 1AGRE 3PVUA 3C7KB 1EMUA 2D9JA 2ODEB 2V4ZB 2IK8B 4TNDA 1EZTA 3KRXA 2GTPC 1FQIA 1EZYA 4MK0A 2EBZA 3NYOA 5HE2A 3CIKA 3PVWA 2DLVA 2JNUA 3V5WA 3KRWA 1FQKB 2OJ4A 3C7LA 3NYNA 1CMZA 2BT2A 5DO9B 2BV1A 2IHBB 5HE1A 2IHDA 4TNBA 2BCJA 3UZTA 1DK8A 2JM5A 5HE3A 2OWIA
chains in the Genus database with same CATH superfamily
4PNKA 1FQJB 2AF0A 5HE0A 3I5QA 4EKDB 2CRPA 3PSCA 1OMWA 1AGRE 3PVUA 3C7KB 1EMUA 2D9JA 2ODEB 2V4ZB 5REQB 2IK8B 4TNDA 1EZTA 3KRXA 2GTPC 1FQIA 1EZYA 4MK0A 2EBZA 3NYOA 5HE2A 3CIKA 3PVWA 2DLVA 2JNUA 3V5WA 3QYFA 3KRWA 1FQKB 2OJ4A 3C7LA 3NYNA 1CMZA 2BT2A 5DO9B 2BV1A 2IHBB 5HE1A 2IHDA 4TNBA 2BCJA 3UZTA 1DK8A 2JM5A 5HE3A 2OWIA 4HTEA
chains in the Genus database with same CATH topology
4PNKA 1FQJB 2AF0A 5HE0A 4EKDB 2CRPA 3PSCA 1OMWA 1AGRE 3PVUA 3C7KB 1EMUA 2D9JA 2ODEB 2V4ZB 5REQB 2IK8B 4TNDA 1EZTA 3KRXA 2GTPC 1FQIA 1EZYA 4MK0A 2EBZA 3NYOA 5HE2A 3CIKA 3PVWA 2DLVA 2JNUA 3V5WA 3QYFA 3KRWA 1FQKB 2OJ4A 3C7LA 3NYNA 1CMZA 2BT2A 5DO9B 2BV1A 2IHBB 5HE1A 2IHDA 4TNBA 2BCJA 3UZTA 1DK8A 2JM5A 5HE3A 2OWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PNK A;  1FQJ B;  2AF0 A;  5HE0 A;  4EKD B;  2CRP A;  3PSC A;  1OMW A;  1AGR E;  3PVU A;  3C7K B;  1EMU A;  2D9J A;  2ODE B;  2V4Z B;  2IK8 B;  4TND A;  1EZT A;  3KRX A;  2GTP C;  1FQI A;  1EZY A;  4MK0 A;  2EBZ A;  3NYO A;  5HE2 A;  3CIK A;  3PVW A;  2DLV A;  2JNU A;  3V5W A;  3KRW A;  1FQK B;  2OJ4 A;  3C7L A;  3NYN A;  1CMZ A;  2BT2 A;  5DO9 B;  2BV1 A;  2IHB B;  5HE1 A;  2IHD A;  4TNB A;  2BCJ A;  3UZT A;  1DK8 A;  2JM5 A;  5HE3 A;  2OWI A; 
#chains in the Genus database with same CATH topology
 4PNK A;  1FQJ B;  2AF0 A;  5HE0 A;  3I5Q A;  4EKD B;  2CRP A;  3PSC A;  1OMW A;  1AGR E;  3PVU A;  3C7K B;  1EMU A;  2D9J A;  2ODE B;  2V4Z B;  5REQ B;  2IK8 B;  4TND A;  1EZT A;  3KRX A;  2GTP C;  1FQI A;  1EZY A;  4MK0 A;  2EBZ A;  3NYO A;  5HE2 A;  3CIK A;  3PVW A;  2DLV A;  2JNU A;  3V5W A;  3QYF A;  3KRW A;  1FQK B;  2OJ4 A;  3C7L A;  3NYN A;  1CMZ A;  2BT2 A;  5DO9 B;  2BV1 A;  2IHB B;  5HE1 A;  2IHD A;  4TNB A;  2BCJ A;  3UZT A;  1DK8 A;  2JM5 A;  5HE3 A;  2OWI A;  4HTE A; 
#chains in the Genus database with same CATH homology
 4PNK A;  1FQJ B;  2AF0 A;  5HE0 A;  4EKD B;  2CRP A;  3PSC A;  1OMW A;  1AGR E;  3PVU A;  3C7K B;  1EMU A;  2D9J A;  2ODE B;  2V4Z B;  5REQ B;  2IK8 B;  4TND A;  1EZT A;  3KRX A;  2GTP C;  1FQI A;  1EZY A;  4MK0 A;  2EBZ A;  3NYO A;  5HE2 A;  3CIK A;  3PVW A;  2DLV A;  2JNU A;  3V5W A;  3QYF A;  3KRW A;  1FQK B;  2OJ4 A;  3C7L A;  3NYN A;  1CMZ A;  2BT2 A;  5DO9 B;  2BV1 A;  2IHB B;  5HE1 A;  2IHD A;  4TNB A;  2BCJ A;  3UZT A;  1DK8 A;  2JM5 A;  5HE3 A;  2OWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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