2IHDA

Crystal structure of human regulator of g-protein signaling 8, rgs8
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
127
structure length
127
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 8
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 51
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihdA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihdA01
2CRPA 5HE3A 5HE0A 1FQKB 1OMWA 3C7LA 3PVUA 5HE2A 2V4ZB 3KRWA 3KRXA 2D9JA 2EBZA 2BCJA 4TNBA 1EMUA 2JM5A 1AGRE 3C7KB 3V5WA 5DO9B 2AF0A 1EZTA 5HE1A 4TNDA 2DLVA 4PNKA 2ODEB 3CIKA 3PVWA 2GTPC 1FQIA 4EKDB 2IK8B 3NYNA 2OWIA 4MK0A 2IHBB 2BV1A 1FQJB 2BT2A 3NYOA 3UZTA 1EZYA 2OJ4A 1DK8A 2IHDA 2JNUA 3PSCA 1CMZA
chains in the Genus database with same CATH superfamily
2CRPA 5HE3A 5HE0A 1FQKB 1OMWA 3C7LA 3PVUA 5HE2A 2V4ZB 3KRWA 3KRXA 2D9JA 2EBZA 2BCJA 4TNBA 1EMUA 2JM5A 1AGRE 3C7KB 3V5WA 4HTEA 5DO9B 2AF0A 1EZTA 3I5QA 5HE1A 5REQB 4TNDA 2DLVA 4PNKA 2ODEB 3CIKA 3PVWA 2GTPC 1FQIA 4EKDB 3QYFA 2IK8B 3NYNA 2OWIA 4MK0A 2IHBB 2BV1A 1FQJB 2BT2A 3NYOA 3UZTA 1EZYA 2OJ4A 1DK8A 2IHDA 2JNUA 3PSCA 1CMZA
chains in the Genus database with same CATH topology
2CRPA 5HE3A 5HE0A 1FQKB 1OMWA 3C7LA 3PVUA 5HE2A 2V4ZB 3KRWA 3KRXA 2D9JA 2EBZA 2BCJA 4TNBA 1EMUA 2JM5A 1AGRE 3C7KB 3V5WA 5DO9B 2AF0A 1EZTA 5HE1A 5REQB 4TNDA 2DLVA 4PNKA 2ODEB 3CIKA 3PVWA 2GTPC 1FQIA 4EKDB 3QYFA 2IK8B 3NYNA 2OWIA 4MK0A 2IHBB 2BV1A 1FQJB 2BT2A 3NYOA 3UZTA 1EZYA 2OJ4A 1DK8A 2IHDA 2JNUA 3PSCA 1CMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CRP A;  5HE3 A;  5HE0 A;  1FQK B;  1OMW A;  3C7L A;  3PVU A;  5HE2 A;  2V4Z B;  3KRW A;  3KRX A;  2D9J A;  2EBZ A;  2BCJ A;  4TNB A;  1EMU A;  2JM5 A;  1AGR E;  3C7K B;  3V5W A;  5DO9 B;  2AF0 A;  1EZT A;  5HE1 A;  4TND A;  2DLV A;  4PNK A;  2ODE B;  3CIK A;  3PVW A;  2GTP C;  1FQI A;  4EKD B;  2IK8 B;  3NYN A;  2OWI A;  4MK0 A;  2IHB B;  2BV1 A;  1FQJ B;  2BT2 A;  3NYO A;  3UZT A;  1EZY A;  2OJ4 A;  1DK8 A;  2IHD A;  2JNU A;  3PSC A;  1CMZ A; 
#chains in the Genus database with same CATH topology
 2CRP A;  5HE3 A;  5HE0 A;  1FQK B;  1OMW A;  3C7L A;  3PVU A;  5HE2 A;  2V4Z B;  3KRW A;  3KRX A;  2D9J A;  2EBZ A;  2BCJ A;  4TNB A;  1EMU A;  2JM5 A;  1AGR E;  3C7K B;  3V5W A;  4HTE A;  5DO9 B;  2AF0 A;  1EZT A;  3I5Q A;  5HE1 A;  5REQ B;  4TND A;  2DLV A;  4PNK A;  2ODE B;  3CIK A;  3PVW A;  2GTP C;  1FQI A;  4EKD B;  3QYF A;  2IK8 B;  3NYN A;  2OWI A;  4MK0 A;  2IHB B;  2BV1 A;  1FQJ B;  2BT2 A;  3NYO A;  3UZT A;  1EZY A;  2OJ4 A;  1DK8 A;  2IHD A;  2JNU A;  3PSC A;  1CMZ A; 
#chains in the Genus database with same CATH homology
 2CRP A;  5HE3 A;  5HE0 A;  1FQK B;  1OMW A;  3C7L A;  3PVU A;  5HE2 A;  2V4Z B;  3KRW A;  3KRX A;  2D9J A;  2EBZ A;  2BCJ A;  4TNB A;  1EMU A;  2JM5 A;  1AGR E;  3C7K B;  3V5W A;  5DO9 B;  2AF0 A;  1EZT A;  5HE1 A;  5REQ B;  4TND A;  2DLV A;  4PNK A;  2ODE B;  3CIK A;  3PVW A;  2GTP C;  1FQI A;  4EKD B;  3QYF A;  2IK8 B;  3NYN A;  2OWI A;  4MK0 A;  2IHB B;  2BV1 A;  1FQJ B;  2BT2 A;  3NYO A;  3UZT A;  1EZY A;  2OJ4 A;  1DK8 A;  2IHD A;  2JNU A;  3PSC A;  1CMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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