1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
2AF0A 5HE1A 2BCJA 1OMWA 2EBZA 2V4ZB 3C7LA 4MK0A 2CRPA 1FQIA 4EKDB 2IHDA 2JM5A 3PVWA 3KRXA 2IK8B 2GTPC 2DLVA 3C7KB 3PSCA 5HE0A 3NYNA 1EMUA 1DK8A 1FQJB 5DO9B 1EZYA 2D9JA 4TNBA 2JNUA 3PVUA 5HE3A 1EZTA 1FQKB 2BT2A 3NYOA 4TNDA 2IHBB 3V5WA 4PNKA 1CMZA 2OWIA 5HE2A 3KRWA 3UZTA 3CIKA 1AGRE 2BV1A 2ODEB 2OJ4A
chains in the Genus database with same CATH superfamily
2AF0A 3QYFA 5HE1A 2BCJA 1OMWA 2EBZA 2V4ZB 3C7LA 4MK0A 2CRPA 1FQIA 4EKDB 2IHDA 4HTEA 2JM5A 3PVWA 3KRXA 2IK8B 2GTPC 2DLVA 3C7KB 3PSCA 5HE0A 3NYNA 1EMUA 1DK8A 1FQJB 5DO9B 1EZYA 2D9JA 4TNBA 2JNUA 3PVUA 5HE3A 1EZTA 1FQKB 2BT2A 3NYOA 4TNDA 2IHBB 3V5WA 4PNKA 1CMZA 2OWIA 5HE2A 3KRWA 3UZTA 3CIKA 1AGRE 2BV1A 2ODEB 5REQB 2OJ4A 3I5QA
chains in the Genus database with same CATH topology
2AF0A 3QYFA 5HE1A 2BCJA 1OMWA 2EBZA 2V4ZB 3C7LA 4MK0A 2CRPA 1FQIA 4EKDB 2IHDA 2JM5A 3PVWA 3KRXA 2IK8B 2GTPC 2DLVA 3C7KB 3PSCA 5HE0A 3NYNA 1EMUA 1DK8A 1FQJB 5DO9B 1EZYA 2D9JA 4TNBA 2JNUA 3PVUA 5HE3A 1EZTA 1FQKB 2BT2A 3NYOA 4TNDA 2IHBB 3V5WA 4PNKA 1CMZA 2OWIA 5HE2A 3KRWA 3UZTA 3CIKA 1AGRE 2BV1A 2ODEB 5REQB 2OJ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AF0 A;  5HE1 A;  2BCJ A;  1OMW A;  2EBZ A;  2V4Z B;  3C7L A;  4MK0 A;  2CRP A;  1FQI A;  4EKD B;  2IHD A;  2JM5 A;  3PVW A;  3KRX A;  2IK8 B;  2GTP C;  2DLV A;  3C7K B;  3PSC A;  5HE0 A;  3NYN A;  1EMU A;  1DK8 A;  1FQJ B;  5DO9 B;  1EZY A;  2D9J A;  4TNB A;  2JNU A;  3PVU A;  5HE3 A;  1EZT A;  1FQK B;  2BT2 A;  3NYO A;  4TND A;  2IHB B;  3V5W A;  4PNK A;  1CMZ A;  2OWI A;  5HE2 A;  3KRW A;  3UZT A;  3CIK A;  1AGR E;  2BV1 A;  2ODE B;  2OJ4 A; 
#chains in the Genus database with same CATH topology
 2AF0 A;  3QYF A;  5HE1 A;  2BCJ A;  1OMW A;  2EBZ A;  2V4Z B;  3C7L A;  4MK0 A;  2CRP A;  1FQI A;  4EKD B;  2IHD A;  4HTE A;  2JM5 A;  3PVW A;  3KRX A;  2IK8 B;  2GTP C;  2DLV A;  3C7K B;  3PSC A;  5HE0 A;  3NYN A;  1EMU A;  1DK8 A;  1FQJ B;  5DO9 B;  1EZY A;  2D9J A;  4TNB A;  2JNU A;  3PVU A;  5HE3 A;  1EZT A;  1FQK B;  2BT2 A;  3NYO A;  4TND A;  2IHB B;  3V5W A;  4PNK A;  1CMZ A;  2OWI A;  5HE2 A;  3KRW A;  3UZT A;  3CIK A;  1AGR E;  2BV1 A;  2ODE B;  5REQ B;  2OJ4 A;  3I5Q A; 
#chains in the Genus database with same CATH homology
 2AF0 A;  3QYF A;  5HE1 A;  2BCJ A;  1OMW A;  2EBZ A;  2V4Z B;  3C7L A;  4MK0 A;  2CRP A;  1FQI A;  4EKD B;  2IHD A;  2JM5 A;  3PVW A;  3KRX A;  2IK8 B;  2GTP C;  2DLV A;  3C7K B;  3PSC A;  5HE0 A;  3NYN A;  1EMU A;  1DK8 A;  1FQJ B;  5DO9 B;  1EZY A;  2D9J A;  4TNB A;  2JNU A;  3PVU A;  5HE3 A;  1EZT A;  1FQK B;  2BT2 A;  3NYO A;  4TND A;  2IHB B;  3V5W A;  4PNK A;  1CMZ A;  2OWI A;  5HE2 A;  3KRW A;  3UZT A;  3CIK A;  1AGR E;  2BV1 A;  2ODE B;  5REQ B;  2OJ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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