1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
source organism Bos taurus
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
5HE1A 2D9JA 1AGRE 3PVUA 3C7LA 2JM5A 2DLVA 2OJ4A 3KRXA 5DO9B 1DK8A 1EZTA 3PSCA 2EBZA 3V5WA 4PNKA 3CIKA 5HE2A 4EKDB 2IK8B 3UZTA 5HE3A 2V4ZB 2BT2A 3PVWA 5HE0A 2OWIA 2JNUA 1OMWA 2BV1A 2IHDA 1EMUA 1FQIA 1FQJB 4TNDA 1EZYA 2BCJA 2ODEB 1CMZA 3C7KB 3KRWA 2GTPC 3NYNA 1FQKB 3NYOA 2AF0A 2CRPA 4TNBA 4MK0A 2IHBB
chains in the Genus database with same CATH superfamily
5HE1A 3QYFA 2D9JA 5REQB 1AGRE 3PVUA 3C7LA 2JM5A 2DLVA 2OJ4A 3KRXA 5DO9B 1DK8A 1EZTA 3PSCA 2EBZA 3V5WA 4PNKA 3CIKA 5HE2A 4EKDB 2IK8B 3UZTA 5HE3A 2V4ZB 2BT2A 3PVWA 4HTEA 5HE0A 2OWIA 2JNUA 1OMWA 2BV1A 2IHDA 1EMUA 1FQIA 1FQJB 4TNDA 1EZYA 2BCJA 2ODEB 1CMZA 3C7KB 3KRWA 2GTPC 3I5QA 3NYNA 1FQKB 3NYOA 2AF0A 2CRPA 4TNBA 4MK0A 2IHBB
chains in the Genus database with same CATH topology
5HE1A 3QYFA 2D9JA 5REQB 1AGRE 3PVUA 3C7LA 2JM5A 2DLVA 2OJ4A 3KRXA 5DO9B 1DK8A 1EZTA 3PSCA 2EBZA 3V5WA 4PNKA 3CIKA 5HE2A 4EKDB 2IK8B 3UZTA 5HE3A 2V4ZB 2BT2A 3PVWA 5HE0A 2OWIA 2JNUA 1OMWA 2BV1A 2IHDA 1EMUA 1FQIA 1FQJB 4TNDA 1EZYA 2BCJA 2ODEB 1CMZA 3C7KB 3KRWA 2GTPC 3NYNA 1FQKB 3NYOA 2AF0A 2CRPA 4TNBA 4MK0A 2IHBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE1 A;  2D9J A;  1AGR E;  3PVU A;  3C7L A;  2JM5 A;  2DLV A;  2OJ4 A;  3KRX A;  5DO9 B;  1DK8 A;  1EZT A;  3PSC A;  2EBZ A;  3V5W A;  4PNK A;  3CIK A;  5HE2 A;  4EKD B;  2IK8 B;  3UZT A;  5HE3 A;  2V4Z B;  2BT2 A;  3PVW A;  5HE0 A;  2OWI A;  2JNU A;  1OMW A;  2BV1 A;  2IHD A;  1EMU A;  1FQI A;  1FQJ B;  4TND A;  1EZY A;  2BCJ A;  2ODE B;  1CMZ A;  3C7K B;  3KRW A;  2GTP C;  3NYN A;  1FQK B;  3NYO A;  2AF0 A;  2CRP A;  4TNB A;  4MK0 A;  2IHB B; 
#chains in the Genus database with same CATH topology
 5HE1 A;  3QYF A;  2D9J A;  5REQ B;  1AGR E;  3PVU A;  3C7L A;  2JM5 A;  2DLV A;  2OJ4 A;  3KRX A;  5DO9 B;  1DK8 A;  1EZT A;  3PSC A;  2EBZ A;  3V5W A;  4PNK A;  3CIK A;  5HE2 A;  4EKD B;  2IK8 B;  3UZT A;  5HE3 A;  2V4Z B;  2BT2 A;  3PVW A;  4HTE A;  5HE0 A;  2OWI A;  2JNU A;  1OMW A;  2BV1 A;  2IHD A;  1EMU A;  1FQI A;  1FQJ B;  4TND A;  1EZY A;  2BCJ A;  2ODE B;  1CMZ A;  3C7K B;  3KRW A;  2GTP C;  3I5Q A;  3NYN A;  1FQK B;  3NYO A;  2AF0 A;  2CRP A;  4TNB A;  4MK0 A;  2IHB B; 
#chains in the Genus database with same CATH homology
 5HE1 A;  3QYF A;  2D9J A;  5REQ B;  1AGR E;  3PVU A;  3C7L A;  2JM5 A;  2DLV A;  2OJ4 A;  3KRX A;  5DO9 B;  1DK8 A;  1EZT A;  3PSC A;  2EBZ A;  3V5W A;  4PNK A;  3CIK A;  5HE2 A;  4EKD B;  2IK8 B;  3UZT A;  5HE3 A;  2V4Z B;  2BT2 A;  3PVW A;  5HE0 A;  2OWI A;  2JNU A;  1OMW A;  2BV1 A;  2IHD A;  1EMU A;  1FQI A;  1FQJ B;  4TND A;  1EZY A;  2BCJ A;  2ODE B;  1CMZ A;  3C7K B;  3KRW A;  2GTP C;  3NYN A;  1FQK B;  3NYO A;  2AF0 A;  2CRP A;  4TNB A;  4MK0 A;  2IHB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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