1DK8A

Crystal structure of the rgs-homologous domain of axin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
147
structure length
147
Chain Sequence
GSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords AXIN
publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
source organism Homo sapiens
total genus 50
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 1999-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1dk8A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1dk8A01
1DK8A 3PSCA 3C7LA 4TNDA 1FQIA 2DLVA 2OWIA 5HE0A 3PVWA 1EMUA 4PNKA 2D9JA 2IHBB 2V4ZB 1EZTA 2IHDA 2OJ4A 2BCJA 3KRWA 2BV1A 1AGRE 5HE3A 3C7KB 3KRXA 1FQKB 2JNUA 5HE2A 2GTPC 3PVUA 1OMWA 2CRPA 2BT2A 2IK8B 2ODEB 3CIKA 3NYNA 4TNBA 4EKDB 2JM5A 3NYOA 3UZTA 3V5WA 4MK0A 5DO9B 5HE1A 2AF0A 1FQJB 2EBZA 1CMZA 1EZYA
chains in the Genus database with same CATH superfamily
1DK8A 3PSCA 3C7LA 4TNDA 1FQIA 2DLVA 2OWIA 5HE0A 3PVWA 1EMUA 4PNKA 2D9JA 2IHBB 2V4ZB 1EZTA 2IHDA 2OJ4A 2BCJA 3KRWA 2BV1A 1AGRE 5HE3A 3C7KB 3QYFA 3KRXA 1FQKB 2JNUA 5HE2A 2GTPC 3PVUA 1OMWA 2CRPA 2BT2A 2IK8B 2ODEB 3CIKA 3NYNA 4TNBA 4EKDB 5REQB 2JM5A 3NYOA 3I5QA 3UZTA 3V5WA 4MK0A 5DO9B 5HE1A 2AF0A 4HTEA 1FQJB 2EBZA 1CMZA 1EZYA
chains in the Genus database with same CATH topology
1DK8A 3PSCA 3C7LA 4TNDA 1FQIA 2DLVA 2OWIA 5HE0A 3PVWA 1EMUA 4PNKA 2D9JA 2IHBB 2V4ZB 1EZTA 2IHDA 2OJ4A 2BCJA 3KRWA 2BV1A 1AGRE 5HE3A 3C7KB 3QYFA 3KRXA 1FQKB 2JNUA 5HE2A 2GTPC 3PVUA 1OMWA 2CRPA 2BT2A 2IK8B 2ODEB 3CIKA 3NYNA 4TNBA 4EKDB 5REQB 2JM5A 3NYOA 3UZTA 3V5WA 4MK0A 5DO9B 5HE1A 2AF0A 1FQJB 2EBZA 1CMZA 1EZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DK8 A;  3PSC A;  3C7L A;  4TND A;  1FQI A;  2DLV A;  2OWI A;  5HE0 A;  3PVW A;  1EMU A;  4PNK A;  2D9J A;  2IHB B;  2V4Z B;  1EZT A;  2IHD A;  2OJ4 A;  2BCJ A;  3KRW A;  2BV1 A;  1AGR E;  5HE3 A;  3C7K B;  3KRX A;  1FQK B;  2JNU A;  5HE2 A;  2GTP C;  3PVU A;  1OMW A;  2CRP A;  2BT2 A;  2IK8 B;  2ODE B;  3CIK A;  3NYN A;  4TNB A;  4EKD B;  2JM5 A;  3NYO A;  3UZT A;  3V5W A;  4MK0 A;  5DO9 B;  5HE1 A;  2AF0 A;  1FQJ B;  2EBZ A;  1CMZ A;  1EZY A; 
#chains in the Genus database with same CATH topology
 1DK8 A;  3PSC A;  3C7L A;  4TND A;  1FQI A;  2DLV A;  2OWI A;  5HE0 A;  3PVW A;  1EMU A;  4PNK A;  2D9J A;  2IHB B;  2V4Z B;  1EZT A;  2IHD A;  2OJ4 A;  2BCJ A;  3KRW A;  2BV1 A;  1AGR E;  5HE3 A;  3C7K B;  3QYF A;  3KRX A;  1FQK B;  2JNU A;  5HE2 A;  2GTP C;  3PVU A;  1OMW A;  2CRP A;  2BT2 A;  2IK8 B;  2ODE B;  3CIK A;  3NYN A;  4TNB A;  4EKD B;  5REQ B;  2JM5 A;  3NYO A;  3I5Q A;  3UZT A;  3V5W A;  4MK0 A;  5DO9 B;  5HE1 A;  2AF0 A;  4HTE A;  1FQJ B;  2EBZ A;  1CMZ A;  1EZY A; 
#chains in the Genus database with same CATH homology
 1DK8 A;  3PSC A;  3C7L A;  4TND A;  1FQI A;  2DLV A;  2OWI A;  5HE0 A;  3PVW A;  1EMU A;  4PNK A;  2D9J A;  2IHB B;  2V4Z B;  1EZT A;  2IHD A;  2OJ4 A;  2BCJ A;  3KRW A;  2BV1 A;  1AGR E;  5HE3 A;  3C7K B;  3QYF A;  3KRX A;  1FQK B;  2JNU A;  5HE2 A;  2GTP C;  3PVU A;  1OMW A;  2CRP A;  2BT2 A;  2IK8 B;  2ODE B;  3CIK A;  3NYN A;  4TNB A;  4EKD B;  5REQ B;  2JM5 A;  3NYO A;  3UZT A;  3V5W A;  4MK0 A;  5DO9 B;  5HE1 A;  2AF0 A;  1FQJ B;  2EBZ A;  1CMZ A;  1EZY A; 
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similar chains in the pdb database (?% sequence similarity)

 
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