1EMUA

Structure of the axin rgs-homologous domain in complex with a samp repeat from apc
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
132
structure length
132
Chain Sequence
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords AXIN
publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
source organism Homo sapiens
total genus 51
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2000-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1emuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1emuA01
5HE3A 1AGRE 1EZYA 1DK8A 2EBZA 2JM5A 3PVWA 1CMZA 5HE0A 3C7LA 3NYNA 3PVUA 2IK8B 2ODEB 2IHBB 1EMUA 4MK0A 2GTPC 4EKDB 2BT2A 3UZTA 2OWIA 4TNDA 4TNBA 5HE1A 2V4ZB 1OMWA 3KRXA 2AF0A 2OJ4A 1EZTA 4PNKA 2CRPA 3PSCA 3NYOA 5DO9B 2BCJA 5HE2A 2BV1A 2JNUA 1FQKB 2D9JA 3C7KB 1FQJB 3V5WA 2IHDA 3KRWA 1FQIA 2DLVA 3CIKA
chains in the Genus database with same CATH superfamily
5HE3A 1AGRE 1EZYA 1DK8A 2EBZA 2JM5A 3PVWA 1CMZA 5HE0A 3C7LA 3NYNA 3PVUA 2IK8B 2ODEB 3I5QA 2IHBB 1EMUA 4MK0A 2GTPC 4EKDB 2BT2A 3UZTA 2OWIA 4TNDA 4TNBA 4HTEA 5HE1A 2V4ZB 1OMWA 3KRXA 2AF0A 2OJ4A 1EZTA 4PNKA 2CRPA 5REQB 3PSCA 3NYOA 5DO9B 2BCJA 5HE2A 3QYFA 2BV1A 2JNUA 1FQKB 2D9JA 3C7KB 1FQJB 3V5WA 2IHDA 3KRWA 1FQIA 2DLVA 3CIKA
chains in the Genus database with same CATH topology
5HE3A 1AGRE 1EZYA 1DK8A 2EBZA 2JM5A 3PVWA 1CMZA 5HE0A 3C7LA 3NYNA 3PVUA 2IK8B 2ODEB 2IHBB 1EMUA 4MK0A 2GTPC 4EKDB 2BT2A 3UZTA 2OWIA 4TNDA 4TNBA 5HE1A 2V4ZB 1OMWA 3KRXA 2AF0A 2OJ4A 1EZTA 4PNKA 2CRPA 5REQB 3PSCA 3NYOA 5DO9B 2BCJA 5HE2A 3QYFA 2BV1A 2JNUA 1FQKB 2D9JA 3C7KB 1FQJB 3V5WA 2IHDA 3KRWA 1FQIA 2DLVA 3CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE3 A;  1AGR E;  1EZY A;  1DK8 A;  2EBZ A;  2JM5 A;  3PVW A;  1CMZ A;  5HE0 A;  3C7L A;  3NYN A;  3PVU A;  2IK8 B;  2ODE B;  2IHB B;  1EMU A;  4MK0 A;  2GTP C;  4EKD B;  2BT2 A;  3UZT A;  2OWI A;  4TND A;  4TNB A;  5HE1 A;  2V4Z B;  1OMW A;  3KRX A;  2AF0 A;  2OJ4 A;  1EZT A;  4PNK A;  2CRP A;  3PSC A;  3NYO A;  5DO9 B;  2BCJ A;  5HE2 A;  2BV1 A;  2JNU A;  1FQK B;  2D9J A;  3C7K B;  1FQJ B;  3V5W A;  2IHD A;  3KRW A;  1FQI A;  2DLV A;  3CIK A; 
#chains in the Genus database with same CATH topology
 5HE3 A;  1AGR E;  1EZY A;  1DK8 A;  2EBZ A;  2JM5 A;  3PVW A;  1CMZ A;  5HE0 A;  3C7L A;  3NYN A;  3PVU A;  2IK8 B;  2ODE B;  3I5Q A;  2IHB B;  1EMU A;  4MK0 A;  2GTP C;  4EKD B;  2BT2 A;  3UZT A;  2OWI A;  4TND A;  4TNB A;  4HTE A;  5HE1 A;  2V4Z B;  1OMW A;  3KRX A;  2AF0 A;  2OJ4 A;  1EZT A;  4PNK A;  2CRP A;  5REQ B;  3PSC A;  3NYO A;  5DO9 B;  2BCJ A;  5HE2 A;  3QYF A;  2BV1 A;  2JNU A;  1FQK B;  2D9J A;  3C7K B;  1FQJ B;  3V5W A;  2IHD A;  3KRW A;  1FQI A;  2DLV A;  3CIK A; 
#chains in the Genus database with same CATH homology
 5HE3 A;  1AGR E;  1EZY A;  1DK8 A;  2EBZ A;  2JM5 A;  3PVW A;  1CMZ A;  5HE0 A;  3C7L A;  3NYN A;  3PVU A;  2IK8 B;  2ODE B;  2IHB B;  1EMU A;  4MK0 A;  2GTP C;  4EKD B;  2BT2 A;  3UZT A;  2OWI A;  4TND A;  4TNB A;  5HE1 A;  2V4Z B;  1OMW A;  3KRX A;  2AF0 A;  2OJ4 A;  1EZT A;  4PNK A;  2CRP A;  5REQ B;  3PSC A;  3NYO A;  5DO9 B;  2BCJ A;  5HE2 A;  3QYF A;  2BV1 A;  2JNU A;  1FQK B;  2D9J A;  3C7K B;  1FQJ B;  3V5W A;  2IHD A;  3KRW A;  1FQI A;  2DLV A;  3CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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