2JM5A

Solution structure of the rgs domain from human rgs18
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
134
structure length
134
Chain Sequence
SMVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 18
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 50
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2006-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jm5A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jm5A01
1OMWA 1FQIA 5HE3A 2GTPC 3C7LA 4EKDB 2V4ZB 1EMUA 3KRXA 4MK0A 3V5WA 4TNDA 5HE2A 4PNKA 3CIKA 3UZTA 5HE0A 2OWIA 1AGRE 3PSCA 2OJ4A 1FQKB 1CMZA 3C7KB 2ODEB 4TNBA 2DLVA 5DO9B 2CRPA 1EZTA 2JM5A 5HE1A 2IHDA 2IK8B 3NYOA 2BT2A 3NYNA 3KRWA 2IHBB 1DK8A 2AF0A 2JNUA 3PVWA 3PVUA 2BV1A 1EZYA 2EBZA 1FQJB 2BCJA 2D9JA
chains in the Genus database with same CATH superfamily
1OMWA 1FQIA 5HE3A 5REQB 2GTPC 3C7LA 4EKDB 2V4ZB 1EMUA 3KRXA 4MK0A 3V5WA 4TNDA 5HE2A 4PNKA 3CIKA 3UZTA 5HE0A 2OWIA 1AGRE 3PSCA 2OJ4A 1FQKB 1CMZA 3C7KB 2ODEB 4TNBA 2DLVA 5DO9B 2CRPA 1EZTA 2JM5A 5HE1A 2IHDA 2IK8B 3NYOA 3QYFA 2BT2A 3NYNA 3KRWA 2IHBB 1DK8A 3I5QA 2AF0A 2JNUA 3PVWA 4HTEA 3PVUA 2BV1A 1EZYA 2EBZA 1FQJB 2BCJA 2D9JA
chains in the Genus database with same CATH topology
1OMWA 1FQIA 5HE3A 5REQB 2GTPC 3C7LA 4EKDB 2V4ZB 1EMUA 3KRXA 4MK0A 3V5WA 4TNDA 5HE2A 4PNKA 3CIKA 3UZTA 5HE0A 2OWIA 1AGRE 3PSCA 2OJ4A 1FQKB 1CMZA 3C7KB 2ODEB 4TNBA 2DLVA 5DO9B 2CRPA 1EZTA 2JM5A 5HE1A 2IHDA 2IK8B 3NYOA 3QYFA 2BT2A 3NYNA 3KRWA 2IHBB 1DK8A 2AF0A 2JNUA 3PVWA 3PVUA 2BV1A 1EZYA 2EBZA 1FQJB 2BCJA 2D9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OMW A;  1FQI A;  5HE3 A;  2GTP C;  3C7L A;  4EKD B;  2V4Z B;  1EMU A;  3KRX A;  4MK0 A;  3V5W A;  4TND A;  5HE2 A;  4PNK A;  3CIK A;  3UZT A;  5HE0 A;  2OWI A;  1AGR E;  3PSC A;  2OJ4 A;  1FQK B;  1CMZ A;  3C7K B;  2ODE B;  4TNB A;  2DLV A;  5DO9 B;  2CRP A;  1EZT A;  2JM5 A;  5HE1 A;  2IHD A;  2IK8 B;  3NYO A;  2BT2 A;  3NYN A;  3KRW A;  2IHB B;  1DK8 A;  2AF0 A;  2JNU A;  3PVW A;  3PVU A;  2BV1 A;  1EZY A;  2EBZ A;  1FQJ B;  2BCJ A;  2D9J A; 
#chains in the Genus database with same CATH topology
 1OMW A;  1FQI A;  5HE3 A;  5REQ B;  2GTP C;  3C7L A;  4EKD B;  2V4Z B;  1EMU A;  3KRX A;  4MK0 A;  3V5W A;  4TND A;  5HE2 A;  4PNK A;  3CIK A;  3UZT A;  5HE0 A;  2OWI A;  1AGR E;  3PSC A;  2OJ4 A;  1FQK B;  1CMZ A;  3C7K B;  2ODE B;  4TNB A;  2DLV A;  5DO9 B;  2CRP A;  1EZT A;  2JM5 A;  5HE1 A;  2IHD A;  2IK8 B;  3NYO A;  3QYF A;  2BT2 A;  3NYN A;  3KRW A;  2IHB B;  1DK8 A;  3I5Q A;  2AF0 A;  2JNU A;  3PVW A;  4HTE A;  3PVU A;  2BV1 A;  1EZY A;  2EBZ A;  1FQJ B;  2BCJ A;  2D9J A; 
#chains in the Genus database with same CATH homology
 1OMW A;  1FQI A;  5HE3 A;  5REQ B;  2GTP C;  3C7L A;  4EKD B;  2V4Z B;  1EMU A;  3KRX A;  4MK0 A;  3V5W A;  4TND A;  5HE2 A;  4PNK A;  3CIK A;  3UZT A;  5HE0 A;  2OWI A;  1AGR E;  3PSC A;  2OJ4 A;  1FQK B;  1CMZ A;  3C7K B;  2ODE B;  4TNB A;  2DLV A;  5DO9 B;  2CRP A;  1EZT A;  2JM5 A;  5HE1 A;  2IHD A;  2IK8 B;  3NYO A;  3QYF A;  2BT2 A;  3NYN A;  3KRW A;  2IHB B;  1DK8 A;  2AF0 A;  2JNU A;  3PVW A;  3PVU A;  2BV1 A;  1EZY A;  2EBZ A;  1FQJ B;  2BCJ A;  2D9J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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