1FQKB

Crystal structure of the heterodimeric complex of the rgs domain of rgs9, and the gt/i1 chimera alpha subunit [(rgs9)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
136
structure length
136
Chain Sequence
LVDIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
total genus 49
structure length 136
sequence length 136
chains with identical sequence D
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqkB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqkB01
3UZTA 2GTPC 2V4ZB 1EMUA 2OJ4A 3KRWA 3NYOA 4EKDB 5HE1A 1EZYA 2OWIA 4TNBA 2DLVA 1FQJB 4TNDA 2EBZA 5DO9B 2ODEB 5HE0A 2BV1A 1OMWA 2CRPA 1EZTA 3PVUA 2AF0A 3C7KB 1FQIA 3NYNA 4PNKA 2IK8B 3PSCA 3CIKA 2D9JA 2IHBB 2IHDA 2JNUA 5HE2A 5HE3A 3V5WA 2BCJA 3PVWA 2JM5A 3KRXA 3C7LA 2BT2A 1CMZA 1DK8A 1FQKB 4MK0A 1AGRE
chains in the Genus database with same CATH superfamily
3UZTA 2GTPC 2V4ZB 1EMUA 2OJ4A 3KRWA 3NYOA 4EKDB 5HE1A 1EZYA 2OWIA 4TNBA 2DLVA 1FQJB 4TNDA 4HTEA 2EBZA 5DO9B 2ODEB 5HE0A 2BV1A 1OMWA 2CRPA 1EZTA 3PVUA 2AF0A 3C7KB 1FQIA 3NYNA 4PNKA 2IK8B 3QYFA 3PSCA 3CIKA 2D9JA 2IHBB 2IHDA 2JNUA 5HE2A 5HE3A 3V5WA 5REQB 2BCJA 3PVWA 2JM5A 3KRXA 3C7LA 2BT2A 3I5QA 1DK8A 1FQKB 4MK0A 1CMZA 1AGRE
chains in the Genus database with same CATH topology
3UZTA 2GTPC 2V4ZB 1EMUA 2OJ4A 3KRWA 3NYOA 4EKDB 5HE1A 1EZYA 2OWIA 4TNBA 2DLVA 1FQJB 4TNDA 2EBZA 5DO9B 2ODEB 5HE0A 2BV1A 1OMWA 2CRPA 1EZTA 3PVUA 2AF0A 3C7KB 1FQIA 3NYNA 4PNKA 2IK8B 3QYFA 3PSCA 3CIKA 2D9JA 2IHBB 2IHDA 2JNUA 5HE2A 5HE3A 3V5WA 5REQB 2BCJA 3PVWA 2JM5A 3KRXA 3C7LA 2BT2A 1CMZA 1DK8A 1FQKB 4MK0A 1AGRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UZT A;  2GTP C;  2V4Z B;  1EMU A;  2OJ4 A;  3KRW A;  3NYO A;  4EKD B;  5HE1 A;  1EZY A;  2OWI A;  4TNB A;  2DLV A;  1FQJ B;  4TND A;  2EBZ A;  5DO9 B;  2ODE B;  5HE0 A;  2BV1 A;  1OMW A;  2CRP A;  1EZT A;  3PVU A;  2AF0 A;  3C7K B;  1FQI A;  3NYN A;  4PNK A;  2IK8 B;  3PSC A;  3CIK A;  2D9J A;  2IHB B;  2IHD A;  2JNU A;  5HE2 A;  5HE3 A;  3V5W A;  2BCJ A;  3PVW A;  2JM5 A;  3KRX A;  3C7L A;  2BT2 A;  1CMZ A;  1DK8 A;  1FQK B;  4MK0 A;  1AGR E; 
#chains in the Genus database with same CATH topology
 3UZT A;  2GTP C;  2V4Z B;  1EMU A;  2OJ4 A;  3KRW A;  3NYO A;  4EKD B;  5HE1 A;  1EZY A;  2OWI A;  4TNB A;  2DLV A;  1FQJ B;  4TND A;  4HTE A;  2EBZ A;  5DO9 B;  2ODE B;  5HE0 A;  2BV1 A;  1OMW A;  2CRP A;  1EZT A;  3PVU A;  2AF0 A;  3C7K B;  1FQI A;  3NYN A;  4PNK A;  2IK8 B;  3QYF A;  3PSC A;  3CIK A;  2D9J A;  2IHB B;  2IHD A;  2JNU A;  5HE2 A;  5HE3 A;  3V5W A;  5REQ B;  2BCJ A;  3PVW A;  2JM5 A;  3KRX A;  3C7L A;  2BT2 A;  3I5Q A;  1DK8 A;  1FQK B;  4MK0 A;  1CMZ A;  1AGR E; 
#chains in the Genus database with same CATH homology
 3UZT A;  2GTP C;  2V4Z B;  1EMU A;  2OJ4 A;  3KRW A;  3NYO A;  4EKD B;  5HE1 A;  1EZY A;  2OWI A;  4TNB A;  2DLV A;  1FQJ B;  4TND A;  2EBZ A;  5DO9 B;  2ODE B;  5HE0 A;  2BV1 A;  1OMW A;  2CRP A;  1EZT A;  3PVU A;  2AF0 A;  3C7K B;  1FQI A;  3NYN A;  4PNK A;  2IK8 B;  3QYF A;  3PSC A;  3CIK A;  2D9J A;  2IHB B;  2IHD A;  2JNU A;  5HE2 A;  5HE3 A;  3V5W A;  5REQ B;  2BCJ A;  3PVW A;  2JM5 A;  3KRX A;  3C7L A;  2BT2 A;  1CMZ A;  1DK8 A;  1FQK B;  4MK0 A;  1AGR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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