1FQKB

Crystal structure of the heterodimeric complex of the rgs domain of rgs9, and the gt/i1 chimera alpha subunit [(rgs9)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
136
structure length
136
Chain Sequence
LVDIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
source organism Bos taurus
total genus 49
structure length 136
sequence length 136
chains with identical sequence D
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqkB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqkB01
2V4ZB 3KRXA 1CMZA 1FQJB 1DK8A 3NYNA 2IK8B 2IHBB 1FQKB 2BCJA 3PSCA 1FQIA 3PVUA 2CRPA 2JNUA 4TNBA 2D9JA 2EBZA 4MK0A 3KRWA 5HE1A 5HE0A 5HE3A 4EKDB 4TNDA 1AGRE 3CIKA 2DLVA 2BV1A 2BT2A 2OJ4A 3PVWA 2ODEB 4PNKA 2JM5A 1OMWA 3NYOA 1EZTA 2IHDA 5DO9B 3C7KB 5HE2A 3V5WA 2AF0A 1EZYA 3C7LA 1EMUA 3UZTA 2OWIA 2GTPC
chains in the Genus database with same CATH superfamily
2V4ZB 3KRXA 1CMZA 1FQJB 1DK8A 4HTEA 3NYNA 2IK8B 2IHBB 1FQKB 2BCJA 3PSCA 1FQIA 3PVUA 2CRPA 2JNUA 4TNBA 2D9JA 2EBZA 4MK0A 3KRWA 5HE1A 5HE0A 5HE3A 4EKDB 4TNDA 1AGRE 3CIKA 2DLVA 2BV1A 2BT2A 2OJ4A 3PVWA 2ODEB 4PNKA 2JM5A 1OMWA 3NYOA 1EZTA 2IHDA 5DO9B 3C7KB 5REQB 5HE2A 3QYFA 3V5WA 2AF0A 1EZYA 3C7LA 1EMUA 3I5QA 3UZTA 2OWIA 2GTPC
chains in the Genus database with same CATH topology
2V4ZB 3KRXA 1CMZA 1FQJB 1DK8A 3NYNA 2IK8B 2IHBB 1FQKB 2BCJA 3PSCA 1FQIA 3PVUA 2CRPA 2JNUA 4TNBA 2D9JA 2EBZA 4MK0A 3KRWA 5HE1A 5HE0A 5HE3A 4EKDB 4TNDA 1AGRE 3CIKA 2DLVA 2BV1A 2BT2A 2OJ4A 3PVWA 2ODEB 4PNKA 2JM5A 1OMWA 3NYOA 1EZTA 2IHDA 5DO9B 3C7KB 5REQB 5HE2A 3QYFA 3V5WA 2AF0A 1EZYA 3C7LA 1EMUA 3UZTA 2OWIA 2GTPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V4Z B;  3KRX A;  1CMZ A;  1FQJ B;  1DK8 A;  3NYN A;  2IK8 B;  2IHB B;  1FQK B;  2BCJ A;  3PSC A;  1FQI A;  3PVU A;  2CRP A;  2JNU A;  4TNB A;  2D9J A;  2EBZ A;  4MK0 A;  3KRW A;  5HE1 A;  5HE0 A;  5HE3 A;  4EKD B;  4TND A;  1AGR E;  3CIK A;  2DLV A;  2BV1 A;  2BT2 A;  2OJ4 A;  3PVW A;  2ODE B;  4PNK A;  2JM5 A;  1OMW A;  3NYO A;  1EZT A;  2IHD A;  5DO9 B;  3C7K B;  5HE2 A;  3V5W A;  2AF0 A;  1EZY A;  3C7L A;  1EMU A;  3UZT A;  2OWI A;  2GTP C; 
#chains in the Genus database with same CATH topology
 2V4Z B;  3KRX A;  1CMZ A;  1FQJ B;  1DK8 A;  4HTE A;  3NYN A;  2IK8 B;  2IHB B;  1FQK B;  2BCJ A;  3PSC A;  1FQI A;  3PVU A;  2CRP A;  2JNU A;  4TNB A;  2D9J A;  2EBZ A;  4MK0 A;  3KRW A;  5HE1 A;  5HE0 A;  5HE3 A;  4EKD B;  4TND A;  1AGR E;  3CIK A;  2DLV A;  2BV1 A;  2BT2 A;  2OJ4 A;  3PVW A;  2ODE B;  4PNK A;  2JM5 A;  1OMW A;  3NYO A;  1EZT A;  2IHD A;  5DO9 B;  3C7K B;  5REQ B;  5HE2 A;  3QYF A;  3V5W A;  2AF0 A;  1EZY A;  3C7L A;  1EMU A;  3I5Q A;  3UZT A;  2OWI A;  2GTP C; 
#chains in the Genus database with same CATH homology
 2V4Z B;  3KRX A;  1CMZ A;  1FQJ B;  1DK8 A;  3NYN A;  2IK8 B;  2IHB B;  1FQK B;  2BCJ A;  3PSC A;  1FQI A;  3PVU A;  2CRP A;  2JNU A;  4TNB A;  2D9J A;  2EBZ A;  4MK0 A;  3KRW A;  5HE1 A;  5HE0 A;  5HE3 A;  4EKD B;  4TND A;  1AGR E;  3CIK A;  2DLV A;  2BV1 A;  2BT2 A;  2OJ4 A;  3PVW A;  2ODE B;  4PNK A;  2JM5 A;  1OMW A;  3NYO A;  1EZT A;  2IHD A;  5DO9 B;  3C7K B;  5REQ B;  5HE2 A;  3QYF A;  3V5W A;  2AF0 A;  1EZY A;  3C7L A;  1EMU A;  3UZT A;  2OWI A;  2GTP C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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