1DK8A

Crystal structure of the rgs-homologous domain of axin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
147
structure length
147
Chain Sequence
GSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule keywords AXIN
molecule tags Signaling protein
source organism Homo sapiens
total genus 50
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 1999-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1dk8A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1dk8A01
3V5WA 2ODEB 1OMWA 3KRWA 3PVWA 2V4ZB 5DO9B 2BT2A 1EZTA 1AGRE 2D9JA 1DK8A 5HE0A 2BV1A 2CRPA 2IHBB 1EZYA 1FQJB 5HE2A 5HE3A 2IHDA 1FQIA 3CIKA 2DLVA 2GTPC 3C7KB 3KRXA 2AF0A 4PNKA 4MK0A 3C7LA 2EBZA 2OWIA 1CMZA 2OJ4A 2JNUA 4TNDA 4TNBA 2IK8B 1FQKB 2JM5A 5HE1A 2BCJA 1EMUA 4EKDB 3NYOA 3PSCA 3PVUA 3UZTA 3NYNA
chains in the Genus database with same CATH superfamily
3V5WA 5REQB 2ODEB 1OMWA 3KRWA 3PVWA 2V4ZB 5DO9B 2BT2A 1EZTA 1AGRE 3I5QA 2D9JA 1DK8A 5HE0A 2BV1A 2CRPA 2IHBB 1EZYA 1FQJB 5HE2A 5HE3A 2IHDA 1FQIA 3CIKA 2DLVA 2GTPC 3C7KB 3KRXA 2AF0A 4PNKA 4MK0A 3QYFA 3C7LA 2EBZA 2OWIA 1CMZA 2OJ4A 2JNUA 4TNDA 4TNBA 2IK8B 1FQKB 4HTEA 2JM5A 5HE1A 2BCJA 1EMUA 4EKDB 3NYOA 3PSCA 3PVUA 3UZTA 3NYNA
chains in the Genus database with same CATH topology
3V5WA 5REQB 2ODEB 1OMWA 3KRWA 3PVWA 2V4ZB 5DO9B 2BT2A 1EZTA 1AGRE 2D9JA 1DK8A 5HE0A 2BV1A 2CRPA 2IHBB 1EZYA 1FQJB 5HE2A 5HE3A 2IHDA 1FQIA 3CIKA 2DLVA 2GTPC 3C7KB 3KRXA 2AF0A 4PNKA 4MK0A 3QYFA 3C7LA 2EBZA 2OWIA 1CMZA 2OJ4A 2JNUA 4TNDA 4TNBA 2IK8B 1FQKB 2JM5A 5HE1A 2BCJA 1EMUA 4EKDB 3NYOA 3PSCA 3PVUA 3UZTA 3NYNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V5W A;  2ODE B;  1OMW A;  3KRW A;  3PVW A;  2V4Z B;  5DO9 B;  2BT2 A;  1EZT A;  1AGR E;  2D9J A;  1DK8 A;  5HE0 A;  2BV1 A;  2CRP A;  2IHB B;  1EZY A;  1FQJ B;  5HE2 A;  5HE3 A;  2IHD A;  1FQI A;  3CIK A;  2DLV A;  2GTP C;  3C7K B;  3KRX A;  2AF0 A;  4PNK A;  4MK0 A;  3C7L A;  2EBZ A;  2OWI A;  1CMZ A;  2OJ4 A;  2JNU A;  4TND A;  4TNB A;  2IK8 B;  1FQK B;  2JM5 A;  5HE1 A;  2BCJ A;  1EMU A;  4EKD B;  3NYO A;  3PSC A;  3PVU A;  3UZT A;  3NYN A; 
#chains in the Genus database with same CATH topology
 3V5W A;  5REQ B;  2ODE B;  1OMW A;  3KRW A;  3PVW A;  2V4Z B;  5DO9 B;  2BT2 A;  1EZT A;  1AGR E;  3I5Q A;  2D9J A;  1DK8 A;  5HE0 A;  2BV1 A;  2CRP A;  2IHB B;  1EZY A;  1FQJ B;  5HE2 A;  5HE3 A;  2IHD A;  1FQI A;  3CIK A;  2DLV A;  2GTP C;  3C7K B;  3KRX A;  2AF0 A;  4PNK A;  4MK0 A;  3QYF A;  3C7L A;  2EBZ A;  2OWI A;  1CMZ A;  2OJ4 A;  2JNU A;  4TND A;  4TNB A;  2IK8 B;  1FQK B;  4HTE A;  2JM5 A;  5HE1 A;  2BCJ A;  1EMU A;  4EKD B;  3NYO A;  3PSC A;  3PVU A;  3UZT A;  3NYN A; 
#chains in the Genus database with same CATH homology
 3V5W A;  5REQ B;  2ODE B;  1OMW A;  3KRW A;  3PVW A;  2V4Z B;  5DO9 B;  2BT2 A;  1EZT A;  1AGR E;  2D9J A;  1DK8 A;  5HE0 A;  2BV1 A;  2CRP A;  2IHB B;  1EZY A;  1FQJ B;  5HE2 A;  5HE3 A;  2IHD A;  1FQI A;  3CIK A;  2DLV A;  2GTP C;  3C7K B;  3KRX A;  2AF0 A;  4PNK A;  4MK0 A;  3QYF A;  3C7L A;  2EBZ A;  2OWI A;  1CMZ A;  2OJ4 A;  2JNU A;  4TND A;  4TNB A;  2IK8 B;  1FQK B;  2JM5 A;  5HE1 A;  2BCJ A;  1EMU A;  4EKD B;  3NYO A;  3PSC A;  3PVU A;  3UZT A;  3NYN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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