1DK8A

Crystal structure of the rgs-homologous domain of axin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
147
structure length
147
Chain Sequence
GSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule keywords AXIN
total genus 50
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 1999-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1dk8A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1dk8A01
1EZTA 2IHBB 1CMZA 1EMUA 1FQJB 5HE1A 1FQKB 2JM5A 3PVWA 3PVUA 3KRXA 3CIKA 2EBZA 1DK8A 2CRPA 3C7KB 2OJ4A 1EZYA 2IHDA 2IK8B 2GTPC 4PNKA 2JNUA 4TNBA 1FQIA 3PSCA 3NYOA 5HE2A 3NYNA 5HE0A 2DLVA 5HE3A 3V5WA 4TNDA 3C7LA 3UZTA 1AGRE 2BT2A 4MK0A 2OWIA 2BCJA 1OMWA 3KRWA 2AF0A 2BV1A 2V4ZB 5DO9B 4EKDB 2ODEB 2D9JA
chains in the Genus database with same CATH superfamily
1EZTA 2IHBB 1CMZA 1EMUA 1FQJB 5HE1A 1FQKB 2JM5A 3PVWA 3PVUA 3KRXA 3CIKA 2EBZA 1DK8A 2CRPA 3C7KB 2OJ4A 1EZYA 2IHDA 2IK8B 2GTPC 4PNKA 2JNUA 4TNBA 1FQIA 3PSCA 3NYOA 5HE2A 3NYNA 5HE0A 3QYFA 2DLVA 4HTEA 5HE3A 3V5WA 4TNDA 5REQB 3C7LA 3UZTA 1AGRE 2BT2A 4MK0A 2OWIA 2BCJA 1OMWA 3KRWA 2AF0A 2BV1A 2V4ZB 5DO9B 3I5QA 4EKDB 2ODEB 2D9JA
chains in the Genus database with same CATH topology
1EZTA 2IHBB 1CMZA 1EMUA 1FQJB 5HE1A 1FQKB 2JM5A 3PVWA 3PVUA 3KRXA 3CIKA 2EBZA 1DK8A 2CRPA 3C7KB 2OJ4A 1EZYA 2IHDA 2IK8B 2GTPC 4PNKA 2JNUA 4TNBA 1FQIA 3PSCA 3NYOA 5HE2A 3NYNA 5HE0A 3QYFA 2DLVA 5HE3A 3V5WA 4TNDA 5REQB 3C7LA 3UZTA 1AGRE 2BT2A 4MK0A 2OWIA 2BCJA 1OMWA 3KRWA 2AF0A 2BV1A 2V4ZB 5DO9B 4EKDB 2ODEB 2D9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZT A;  2IHB B;  1CMZ A;  1EMU A;  1FQJ B;  5HE1 A;  1FQK B;  2JM5 A;  3PVW A;  3PVU A;  3KRX A;  3CIK A;  2EBZ A;  1DK8 A;  2CRP A;  3C7K B;  2OJ4 A;  1EZY A;  2IHD A;  2IK8 B;  2GTP C;  4PNK A;  2JNU A;  4TNB A;  1FQI A;  3PSC A;  3NYO A;  5HE2 A;  3NYN A;  5HE0 A;  2DLV A;  5HE3 A;  3V5W A;  4TND A;  3C7L A;  3UZT A;  1AGR E;  2BT2 A;  4MK0 A;  2OWI A;  2BCJ A;  1OMW A;  3KRW A;  2AF0 A;  2BV1 A;  2V4Z B;  5DO9 B;  4EKD B;  2ODE B;  2D9J A; 
#chains in the Genus database with same CATH topology
 1EZT A;  2IHB B;  1CMZ A;  1EMU A;  1FQJ B;  5HE1 A;  1FQK B;  2JM5 A;  3PVW A;  3PVU A;  3KRX A;  3CIK A;  2EBZ A;  1DK8 A;  2CRP A;  3C7K B;  2OJ4 A;  1EZY A;  2IHD A;  2IK8 B;  2GTP C;  4PNK A;  2JNU A;  4TNB A;  1FQI A;  3PSC A;  3NYO A;  5HE2 A;  3NYN A;  5HE0 A;  3QYF A;  2DLV A;  4HTE A;  5HE3 A;  3V5W A;  4TND A;  5REQ B;  3C7L A;  3UZT A;  1AGR E;  2BT2 A;  4MK0 A;  2OWI A;  2BCJ A;  1OMW A;  3KRW A;  2AF0 A;  2BV1 A;  2V4Z B;  5DO9 B;  3I5Q A;  4EKD B;  2ODE B;  2D9J A; 
#chains in the Genus database with same CATH homology
 1EZT A;  2IHB B;  1CMZ A;  1EMU A;  1FQJ B;  5HE1 A;  1FQK B;  2JM5 A;  3PVW A;  3PVU A;  3KRX A;  3CIK A;  2EBZ A;  1DK8 A;  2CRP A;  3C7K B;  2OJ4 A;  1EZY A;  2IHD A;  2IK8 B;  2GTP C;  4PNK A;  2JNU A;  4TNB A;  1FQI A;  3PSC A;  3NYO A;  5HE2 A;  3NYN A;  5HE0 A;  3QYF A;  2DLV A;  5HE3 A;  3V5W A;  4TND A;  5REQ B;  3C7L A;  3UZT A;  1AGR E;  2BT2 A;  4MK0 A;  2OWI A;  2BCJ A;  1OMW A;  3KRW A;  2AF0 A;  2BV1 A;  2V4Z B;  5DO9 B;  4EKD B;  2ODE B;  2D9J A; 
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similar chains in the pdb database (?% sequence similarity)

 
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