1DK8A

Crystal structure of the rgs-homologous domain of axin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
147
structure length
147
Chain Sequence
GSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords AXIN
total genus 50
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 1999-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1dk8A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1dk8A01
3NYNA 1DK8A 2OJ4A 2CRPA 1OMWA 5HE3A 2BCJA 1EMUA 3V5WA 2IK8B 5DO9B 3CIKA 2JNUA 2IHDA 5HE2A 2V4ZB 2OWIA 2AF0A 1CMZA 5HE0A 1FQKB 3NYOA 2JM5A 4TNDA 3UZTA 1FQJB 1AGRE 3PSCA 4TNBA 3PVWA 1EZTA 2BT2A 3KRWA 2D9JA 4EKDB 1EZYA 3C7LA 4PNKA 2DLVA 1FQIA 3C7KB 2BV1A 2ODEB 3KRXA 3PVUA 2EBZA 4MK0A 2IHBB 5HE1A 2GTPC
chains in the Genus database with same CATH superfamily
3NYNA 1DK8A 2OJ4A 2CRPA 1OMWA 5HE3A 2BCJA 1EMUA 3V5WA 2IK8B 5DO9B 3CIKA 2JNUA 3QYFA 2IHDA 5HE2A 2V4ZB 3I5QA 2OWIA 2AF0A 1CMZA 5HE0A 1FQKB 3NYOA 2JM5A 4TNDA 3UZTA 1FQJB 1AGRE 3PSCA 4TNBA 3PVWA 1EZTA 2BT2A 3KRWA 2D9JA 5REQB 4EKDB 1EZYA 3C7LA 4PNKA 2DLVA 1FQIA 4HTEA 3C7KB 2BV1A 2ODEB 3KRXA 3PVUA 2EBZA 4MK0A 2IHBB 5HE1A 2GTPC
chains in the Genus database with same CATH topology
3NYNA 1DK8A 2OJ4A 2CRPA 1OMWA 5HE3A 2BCJA 1EMUA 3V5WA 2IK8B 5DO9B 3CIKA 2JNUA 3QYFA 2IHDA 5HE2A 2V4ZB 2OWIA 2AF0A 1CMZA 5HE0A 1FQKB 3NYOA 2JM5A 4TNDA 3UZTA 1FQJB 1AGRE 3PSCA 4TNBA 3PVWA 1EZTA 2BT2A 3KRWA 2D9JA 5REQB 4EKDB 1EZYA 3C7LA 4PNKA 2DLVA 1FQIA 3C7KB 2BV1A 2ODEB 3KRXA 3PVUA 2EBZA 4MK0A 2IHBB 5HE1A 2GTPC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NYN A;  1DK8 A;  2OJ4 A;  2CRP A;  1OMW A;  5HE3 A;  2BCJ A;  1EMU A;  3V5W A;  2IK8 B;  5DO9 B;  3CIK A;  2JNU A;  2IHD A;  5HE2 A;  2V4Z B;  2OWI A;  2AF0 A;  1CMZ A;  5HE0 A;  1FQK B;  3NYO A;  2JM5 A;  4TND A;  3UZT A;  1FQJ B;  1AGR E;  3PSC A;  4TNB A;  3PVW A;  1EZT A;  2BT2 A;  3KRW A;  2D9J A;  4EKD B;  1EZY A;  3C7L A;  4PNK A;  2DLV A;  1FQI A;  3C7K B;  2BV1 A;  2ODE B;  3KRX A;  3PVU A;  2EBZ A;  4MK0 A;  2IHB B;  5HE1 A;  2GTP C; 
#chains in the Genus database with same CATH topology
 3NYN A;  1DK8 A;  2OJ4 A;  2CRP A;  1OMW A;  5HE3 A;  2BCJ A;  1EMU A;  3V5W A;  2IK8 B;  5DO9 B;  3CIK A;  2JNU A;  3QYF A;  2IHD A;  5HE2 A;  2V4Z B;  3I5Q A;  2OWI A;  2AF0 A;  1CMZ A;  5HE0 A;  1FQK B;  3NYO A;  2JM5 A;  4TND A;  3UZT A;  1FQJ B;  1AGR E;  3PSC A;  4TNB A;  3PVW A;  1EZT A;  2BT2 A;  3KRW A;  2D9J A;  5REQ B;  4EKD B;  1EZY A;  3C7L A;  4PNK A;  2DLV A;  1FQI A;  4HTE A;  3C7K B;  2BV1 A;  2ODE B;  3KRX A;  3PVU A;  2EBZ A;  4MK0 A;  2IHB B;  5HE1 A;  2GTP C; 
#chains in the Genus database with same CATH homology
 3NYN A;  1DK8 A;  2OJ4 A;  2CRP A;  1OMW A;  5HE3 A;  2BCJ A;  1EMU A;  3V5W A;  2IK8 B;  5DO9 B;  3CIK A;  2JNU A;  3QYF A;  2IHD A;  5HE2 A;  2V4Z B;  2OWI A;  2AF0 A;  1CMZ A;  5HE0 A;  1FQK B;  3NYO A;  2JM5 A;  4TND A;  3UZT A;  1FQJ B;  1AGR E;  3PSC A;  4TNB A;  3PVW A;  1EZT A;  2BT2 A;  3KRW A;  2D9J A;  5REQ B;  4EKD B;  1EZY A;  3C7L A;  4PNK A;  2DLV A;  1FQI A;  3C7K B;  2BV1 A;  2ODE B;  3KRX A;  3PVU A;  2EBZ A;  4MK0 A;  2IHB B;  5HE1 A;  2GTP C; 
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