1EMUA

Structure of the axin rgs-homologous domain in complex with a samp repeat from apc
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
132
structure length
132
Chain Sequence
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords AXIN
total genus 51
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2000-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1emuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1emuA01
1OMWA 4EKDB 2OJ4A 3C7KB 2IHDA 1FQIA 4TNDA 2BT2A 3NYOA 3PSCA 1AGRE 1FQJB 2JM5A 1FQKB 2D9JA 3UZTA 4MK0A 3KRXA 2BCJA 3PVUA 2V4ZB 3C7LA 3NYNA 2EBZA 2GTPC 5HE1A 5HE2A 5DO9B 2IK8B 5HE0A 2OWIA 1EZYA 1CMZA 2DLVA 3V5WA 2IHBB 2ODEB 1EMUA 3CIKA 5HE3A 3KRWA 2BV1A 4PNKA 1EZTA 2JNUA 1DK8A 2CRPA 4TNBA 2AF0A 3PVWA
chains in the Genus database with same CATH superfamily
1OMWA 4EKDB 2OJ4A 3C7KB 2IHDA 1FQIA 4TNDA 2BT2A 3NYOA 3PSCA 1AGRE 1FQJB 2JM5A 1FQKB 2D9JA 3UZTA 4MK0A 3KRXA 2BCJA 3PVUA 2V4ZB 3C7LA 3NYNA 2EBZA 2GTPC 5HE1A 3I5QA 5HE2A 5DO9B 2IK8B 5HE0A 2OWIA 1EZYA 1CMZA 5REQB 3QYFA 2DLVA 3V5WA 2IHBB 2ODEB 1EMUA 3CIKA 4HTEA 5HE3A 3KRWA 2BV1A 4PNKA 1EZTA 2JNUA 1DK8A 2CRPA 4TNBA 2AF0A 3PVWA
chains in the Genus database with same CATH topology
1OMWA 4EKDB 2OJ4A 3C7KB 2IHDA 1FQIA 4TNDA 2BT2A 3NYOA 3PSCA 1AGRE 1FQJB 2JM5A 1FQKB 2D9JA 3UZTA 4MK0A 3KRXA 2BCJA 3PVUA 2V4ZB 3C7LA 3NYNA 2EBZA 2GTPC 5HE1A 5HE2A 5DO9B 2IK8B 5HE0A 2OWIA 1EZYA 1CMZA 5REQB 3QYFA 2DLVA 3V5WA 2IHBB 2ODEB 1EMUA 3CIKA 5HE3A 3KRWA 2BV1A 4PNKA 1EZTA 2JNUA 1DK8A 2CRPA 4TNBA 2AF0A 3PVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OMW A;  4EKD B;  2OJ4 A;  3C7K B;  2IHD A;  1FQI A;  4TND A;  2BT2 A;  3NYO A;  3PSC A;  1AGR E;  1FQJ B;  2JM5 A;  1FQK B;  2D9J A;  3UZT A;  4MK0 A;  3KRX A;  2BCJ A;  3PVU A;  2V4Z B;  3C7L A;  3NYN A;  2EBZ A;  2GTP C;  5HE1 A;  5HE2 A;  5DO9 B;  2IK8 B;  5HE0 A;  2OWI A;  1EZY A;  1CMZ A;  2DLV A;  3V5W A;  2IHB B;  2ODE B;  1EMU A;  3CIK A;  5HE3 A;  3KRW A;  2BV1 A;  4PNK A;  1EZT A;  2JNU A;  1DK8 A;  2CRP A;  4TNB A;  2AF0 A;  3PVW A; 
#chains in the Genus database with same CATH topology
 1OMW A;  4EKD B;  2OJ4 A;  3C7K B;  2IHD A;  1FQI A;  4TND A;  2BT2 A;  3NYO A;  3PSC A;  1AGR E;  1FQJ B;  2JM5 A;  1FQK B;  2D9J A;  3UZT A;  4MK0 A;  3KRX A;  2BCJ A;  3PVU A;  2V4Z B;  3C7L A;  3NYN A;  2EBZ A;  2GTP C;  5HE1 A;  3I5Q A;  5HE2 A;  5DO9 B;  2IK8 B;  5HE0 A;  2OWI A;  1EZY A;  1CMZ A;  5REQ B;  3QYF A;  2DLV A;  3V5W A;  2IHB B;  2ODE B;  1EMU A;  3CIK A;  4HTE A;  5HE3 A;  3KRW A;  2BV1 A;  4PNK A;  1EZT A;  2JNU A;  1DK8 A;  2CRP A;  4TNB A;  2AF0 A;  3PVW A; 
#chains in the Genus database with same CATH homology
 1OMW A;  4EKD B;  2OJ4 A;  3C7K B;  2IHD A;  1FQI A;  4TND A;  2BT2 A;  3NYO A;  3PSC A;  1AGR E;  1FQJ B;  2JM5 A;  1FQK B;  2D9J A;  3UZT A;  4MK0 A;  3KRX A;  2BCJ A;  3PVU A;  2V4Z B;  3C7L A;  3NYN A;  2EBZ A;  2GTP C;  5HE1 A;  5HE2 A;  5DO9 B;  2IK8 B;  5HE0 A;  2OWI A;  1EZY A;  1CMZ A;  5REQ B;  3QYF A;  2DLV A;  3V5W A;  2IHB B;  2ODE B;  1EMU A;  3CIK A;  5HE3 A;  3KRW A;  2BV1 A;  4PNK A;  1EZT A;  2JNU A;  1DK8 A;  2CRP A;  4TNB A;  2AF0 A;  3PVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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