1EMUA

Structure of the axin rgs-homologous domain in complex with a samp repeat from apc
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
132
structure length
132
Chain Sequence
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords AXIN
total genus 51
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2000-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1emuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1emuA01
2OJ4A 5HE2A 1OMWA 3UZTA 1EZYA 3C7KB 3PVUA 2JM5A 4MK0A 1FQJB 1EMUA 3PVWA 2D9JA 2BT2A 3CIKA 1FQKB 2JNUA 4PNKA 2BV1A 4TNBA 2AF0A 5DO9B 3NYNA 5HE1A 2V4ZB 3C7LA 2DLVA 2IHDA 1FQIA 2ODEB 4TNDA 2IHBB 2OWIA 4EKDB 1CMZA 2CRPA 3KRXA 3V5WA 2BCJA 1DK8A 2GTPC 5HE0A 1EZTA 2EBZA 2IK8B 1AGRE 3PSCA 5HE3A 3KRWA 3NYOA
chains in the Genus database with same CATH superfamily
2OJ4A 5HE2A 1OMWA 3UZTA 1EZYA 3C7KB 3PVUA 2JM5A 4MK0A 5REQB 1FQJB 1EMUA 3PVWA 2D9JA 3QYFA 3I5QA 2BT2A 3CIKA 1FQKB 2JNUA 4PNKA 2BV1A 4TNBA 2AF0A 5DO9B 3NYNA 5HE1A 4HTEA 2V4ZB 3C7LA 2DLVA 2IHDA 1FQIA 2ODEB 4TNDA 2IHBB 2OWIA 4EKDB 1CMZA 2CRPA 3KRXA 3V5WA 2BCJA 1DK8A 2GTPC 5HE0A 1EZTA 2EBZA 2IK8B 1AGRE 3PSCA 5HE3A 3KRWA 3NYOA
chains in the Genus database with same CATH topology
2OJ4A 5HE2A 1OMWA 3UZTA 1EZYA 3C7KB 3PVUA 2JM5A 4MK0A 5REQB 1FQJB 1EMUA 3PVWA 2D9JA 3QYFA 2BT2A 3CIKA 1FQKB 2JNUA 4PNKA 2BV1A 4TNBA 2AF0A 5DO9B 3NYNA 5HE1A 2V4ZB 3C7LA 2DLVA 2IHDA 1FQIA 2ODEB 4TNDA 2IHBB 2OWIA 4EKDB 1CMZA 2CRPA 3KRXA 3V5WA 2BCJA 1DK8A 2GTPC 5HE0A 1EZTA 2EBZA 2IK8B 1AGRE 3PSCA 5HE3A 3KRWA 3NYOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OJ4 A;  5HE2 A;  1OMW A;  3UZT A;  1EZY A;  3C7K B;  3PVU A;  2JM5 A;  4MK0 A;  1FQJ B;  1EMU A;  3PVW A;  2D9J A;  2BT2 A;  3CIK A;  1FQK B;  2JNU A;  4PNK A;  2BV1 A;  4TNB A;  2AF0 A;  5DO9 B;  3NYN A;  5HE1 A;  2V4Z B;  3C7L A;  2DLV A;  2IHD A;  1FQI A;  2ODE B;  4TND A;  2IHB B;  2OWI A;  4EKD B;  1CMZ A;  2CRP A;  3KRX A;  3V5W A;  2BCJ A;  1DK8 A;  2GTP C;  5HE0 A;  1EZT A;  2EBZ A;  2IK8 B;  1AGR E;  3PSC A;  5HE3 A;  3KRW A;  3NYO A; 
#chains in the Genus database with same CATH topology
 2OJ4 A;  5HE2 A;  1OMW A;  3UZT A;  1EZY A;  3C7K B;  3PVU A;  2JM5 A;  4MK0 A;  5REQ B;  1FQJ B;  1EMU A;  3PVW A;  2D9J A;  3QYF A;  3I5Q A;  2BT2 A;  3CIK A;  1FQK B;  2JNU A;  4PNK A;  2BV1 A;  4TNB A;  2AF0 A;  5DO9 B;  3NYN A;  5HE1 A;  4HTE A;  2V4Z B;  3C7L A;  2DLV A;  2IHD A;  1FQI A;  2ODE B;  4TND A;  2IHB B;  2OWI A;  4EKD B;  1CMZ A;  2CRP A;  3KRX A;  3V5W A;  2BCJ A;  1DK8 A;  2GTP C;  5HE0 A;  1EZT A;  2EBZ A;  2IK8 B;  1AGR E;  3PSC A;  5HE3 A;  3KRW A;  3NYO A; 
#chains in the Genus database with same CATH homology
 2OJ4 A;  5HE2 A;  1OMW A;  3UZT A;  1EZY A;  3C7K B;  3PVU A;  2JM5 A;  4MK0 A;  5REQ B;  1FQJ B;  1EMU A;  3PVW A;  2D9J A;  3QYF A;  2BT2 A;  3CIK A;  1FQK B;  2JNU A;  4PNK A;  2BV1 A;  4TNB A;  2AF0 A;  5DO9 B;  3NYN A;  5HE1 A;  2V4Z B;  3C7L A;  2DLV A;  2IHD A;  1FQI A;  2ODE B;  4TND A;  2IHB B;  2OWI A;  4EKD B;  1CMZ A;  2CRP A;  3KRX A;  3V5W A;  2BCJ A;  1DK8 A;  2GTP C;  5HE0 A;  1EZT A;  2EBZ A;  2IK8 B;  1AGR E;  3PSC A;  5HE3 A;  3KRW A;  3NYO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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