1EMUA

Structure of the axin rgs-homologous domain in complex with a samp repeat from apc
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
132
structure length
132
Chain Sequence
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
molecule keywords AXIN
molecule tags Signaling protein
source organism Homo sapiens
total genus 51
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2000-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1emuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1emuA01
2CRPA 2BT2A 2IK8B 3UZTA 1FQIA 3NYOA 2EBZA 3PSCA 1CMZA 4EKDB 3V5WA 5HE0A 2BCJA 2IHBB 4MK0A 2ODEB 5HE2A 2AF0A 1FQKB 1AGRE 3C7LA 2V4ZB 2JM5A 2DLVA 1EZTA 1OMWA 2JNUA 5HE3A 1FQJB 5DO9B 3CIKA 1EMUA 1EZYA 1DK8A 3KRXA 3KRWA 4TNBA 3C7KB 2IHDA 2D9JA 4PNKA 2BV1A 2OWIA 3PVUA 2OJ4A 3PVWA 4TNDA 2GTPC 3NYNA 5HE1A
chains in the Genus database with same CATH superfamily
2CRPA 2BT2A 2IK8B 3UZTA 1FQIA 3NYOA 2EBZA 3PSCA 1CMZA 4EKDB 3V5WA 5HE0A 2BCJA 2IHBB 4MK0A 2ODEB 4HTEA 5HE2A 2AF0A 1FQKB 1AGRE 3C7LA 2V4ZB 2JM5A 3QYFA 2DLVA 1EZTA 1OMWA 2JNUA 5HE3A 1FQJB 5DO9B 3CIKA 5REQB 1EMUA 1EZYA 1DK8A 3KRXA 3I5QA 3KRWA 4TNBA 3C7KB 2IHDA 2D9JA 4PNKA 2BV1A 2OWIA 3PVUA 2OJ4A 3PVWA 4TNDA 2GTPC 3NYNA 5HE1A
chains in the Genus database with same CATH topology
2CRPA 2BT2A 2IK8B 3UZTA 1FQIA 3NYOA 2EBZA 3PSCA 1CMZA 4EKDB 3V5WA 5HE0A 2BCJA 2IHBB 4MK0A 2ODEB 5HE2A 2AF0A 1FQKB 1AGRE 3C7LA 2V4ZB 2JM5A 3QYFA 2DLVA 1EZTA 1OMWA 2JNUA 5HE3A 1FQJB 5DO9B 3CIKA 5REQB 1EMUA 1EZYA 1DK8A 3KRXA 3KRWA 4TNBA 3C7KB 2IHDA 2D9JA 4PNKA 2BV1A 2OWIA 3PVUA 2OJ4A 3PVWA 4TNDA 2GTPC 3NYNA 5HE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CRP A;  2BT2 A;  2IK8 B;  3UZT A;  1FQI A;  3NYO A;  2EBZ A;  3PSC A;  1CMZ A;  4EKD B;  3V5W A;  5HE0 A;  2BCJ A;  2IHB B;  4MK0 A;  2ODE B;  5HE2 A;  2AF0 A;  1FQK B;  1AGR E;  3C7L A;  2V4Z B;  2JM5 A;  2DLV A;  1EZT A;  1OMW A;  2JNU A;  5HE3 A;  1FQJ B;  5DO9 B;  3CIK A;  1EMU A;  1EZY A;  1DK8 A;  3KRX A;  3KRW A;  4TNB A;  3C7K B;  2IHD A;  2D9J A;  4PNK A;  2BV1 A;  2OWI A;  3PVU A;  2OJ4 A;  3PVW A;  4TND A;  2GTP C;  3NYN A;  5HE1 A; 
#chains in the Genus database with same CATH topology
 2CRP A;  2BT2 A;  2IK8 B;  3UZT A;  1FQI A;  3NYO A;  2EBZ A;  3PSC A;  1CMZ A;  4EKD B;  3V5W A;  5HE0 A;  2BCJ A;  2IHB B;  4MK0 A;  2ODE B;  4HTE A;  5HE2 A;  2AF0 A;  1FQK B;  1AGR E;  3C7L A;  2V4Z B;  2JM5 A;  3QYF A;  2DLV A;  1EZT A;  1OMW A;  2JNU A;  5HE3 A;  1FQJ B;  5DO9 B;  3CIK A;  5REQ B;  1EMU A;  1EZY A;  1DK8 A;  3KRX A;  3I5Q A;  3KRW A;  4TNB A;  3C7K B;  2IHD A;  2D9J A;  4PNK A;  2BV1 A;  2OWI A;  3PVU A;  2OJ4 A;  3PVW A;  4TND A;  2GTP C;  3NYN A;  5HE1 A; 
#chains in the Genus database with same CATH homology
 2CRP A;  2BT2 A;  2IK8 B;  3UZT A;  1FQI A;  3NYO A;  2EBZ A;  3PSC A;  1CMZ A;  4EKD B;  3V5W A;  5HE0 A;  2BCJ A;  2IHB B;  4MK0 A;  2ODE B;  5HE2 A;  2AF0 A;  1FQK B;  1AGR E;  3C7L A;  2V4Z B;  2JM5 A;  3QYF A;  2DLV A;  1EZT A;  1OMW A;  2JNU A;  5HE3 A;  1FQJ B;  5DO9 B;  3CIK A;  5REQ B;  1EMU A;  1EZY A;  1DK8 A;  3KRX A;  3KRW A;  4TNB A;  3C7K B;  2IHD A;  2D9J A;  4PNK A;  2BV1 A;  2OWI A;  3PVU A;  2OJ4 A;  3PVW A;  4TND A;  2GTP C;  3NYN A;  5HE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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