1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
3C7LA 4MK0A 2JM5A 5HE3A 4EKDB 3C7KB 3CIKA 2IK8B 5DO9B 2OJ4A 1EMUA 2GTPC 4TNDA 5HE2A 5HE0A 3UZTA 1AGRE 3PVWA 2CRPA 4TNBA 2DLVA 5HE1A 1FQJB 1DK8A 3KRWA 3PSCA 2BCJA 1CMZA 1OMWA 2BV1A 2BT2A 2IHBB 2JNUA 2ODEB 1FQIA 3NYOA 1FQKB 3PVUA 1EZYA 2IHDA 2V4ZB 2AF0A 3KRXA 3NYNA 2D9JA 2OWIA 3V5WA 4PNKA 1EZTA 2EBZA
chains in the Genus database with same CATH superfamily
3C7LA 4MK0A 2JM5A 5HE3A 4EKDB 3C7KB 3CIKA 2IK8B 5DO9B 2OJ4A 1EMUA 2GTPC 4TNDA 5HE2A 5HE0A 3UZTA 1AGRE 3PVWA 2CRPA 4TNBA 2DLVA 5HE1A 1FQJB 1DK8A 3KRWA 3PSCA 2BCJA 1CMZA 1OMWA 2BV1A 2BT2A 3QYFA 2IHBB 2JNUA 2ODEB 5REQB 1FQIA 3NYOA 1FQKB 3PVUA 1EZYA 2IHDA 2V4ZB 2AF0A 3KRXA 3NYNA 2D9JA 4HTEA 2OWIA 3I5QA 3V5WA 4PNKA 1EZTA 2EBZA
chains in the Genus database with same CATH topology
3C7LA 4MK0A 2JM5A 5HE3A 4EKDB 3C7KB 3CIKA 2IK8B 5DO9B 2OJ4A 1EMUA 2GTPC 4TNDA 5HE2A 5HE0A 3UZTA 1AGRE 3PVWA 2CRPA 4TNBA 2DLVA 5HE1A 1FQJB 1DK8A 3KRWA 3PSCA 2BCJA 1CMZA 1OMWA 2BV1A 2BT2A 3QYFA 2IHBB 2JNUA 2ODEB 5REQB 1FQIA 3NYOA 1FQKB 3PVUA 1EZYA 2IHDA 2V4ZB 2AF0A 3KRXA 3NYNA 2D9JA 2OWIA 3V5WA 4PNKA 1EZTA 2EBZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C7L A;  4MK0 A;  2JM5 A;  5HE3 A;  4EKD B;  3C7K B;  3CIK A;  2IK8 B;  5DO9 B;  2OJ4 A;  1EMU A;  2GTP C;  4TND A;  5HE2 A;  5HE0 A;  3UZT A;  1AGR E;  3PVW A;  2CRP A;  4TNB A;  2DLV A;  5HE1 A;  1FQJ B;  1DK8 A;  3KRW A;  3PSC A;  2BCJ A;  1CMZ A;  1OMW A;  2BV1 A;  2BT2 A;  2IHB B;  2JNU A;  2ODE B;  1FQI A;  3NYO A;  1FQK B;  3PVU A;  1EZY A;  2IHD A;  2V4Z B;  2AF0 A;  3KRX A;  3NYN A;  2D9J A;  2OWI A;  3V5W A;  4PNK A;  1EZT A;  2EBZ A; 
#chains in the Genus database with same CATH topology
 3C7L A;  4MK0 A;  2JM5 A;  5HE3 A;  4EKD B;  3C7K B;  3CIK A;  2IK8 B;  5DO9 B;  2OJ4 A;  1EMU A;  2GTP C;  4TND A;  5HE2 A;  5HE0 A;  3UZT A;  1AGR E;  3PVW A;  2CRP A;  4TNB A;  2DLV A;  5HE1 A;  1FQJ B;  1DK8 A;  3KRW A;  3PSC A;  2BCJ A;  1CMZ A;  1OMW A;  2BV1 A;  2BT2 A;  3QYF A;  2IHB B;  2JNU A;  2ODE B;  5REQ B;  1FQI A;  3NYO A;  1FQK B;  3PVU A;  1EZY A;  2IHD A;  2V4Z B;  2AF0 A;  3KRX A;  3NYN A;  2D9J A;  4HTE A;  2OWI A;  3I5Q A;  3V5W A;  4PNK A;  1EZT A;  2EBZ A; 
#chains in the Genus database with same CATH homology
 3C7L A;  4MK0 A;  2JM5 A;  5HE3 A;  4EKD B;  3C7K B;  3CIK A;  2IK8 B;  5DO9 B;  2OJ4 A;  1EMU A;  2GTP C;  4TND A;  5HE2 A;  5HE0 A;  3UZT A;  1AGR E;  3PVW A;  2CRP A;  4TNB A;  2DLV A;  5HE1 A;  1FQJ B;  1DK8 A;  3KRW A;  3PSC A;  2BCJ A;  1CMZ A;  1OMW A;  2BV1 A;  2BT2 A;  3QYF A;  2IHB B;  2JNU A;  2ODE B;  5REQ B;  1FQI A;  3NYO A;  1FQK B;  3PVU A;  1EZY A;  2IHD A;  2V4Z B;  2AF0 A;  3KRX A;  3NYN A;  2D9J A;  2OWI A;  3V5W A;  4PNK A;  1EZT A;  2EBZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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