1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
molecule tags Signaling protein
source organism Bos taurus
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
2IHDA 1AGRE 2BV1A 1EZYA 2OWIA 1FQIA 1EMUA 5HE1A 5HE3A 2DLVA 2BT2A 3PSCA 2JM5A 5HE2A 1DK8A 1OMWA 2GTPC 2ODEB 3KRWA 4TNBA 1FQKB 3NYNA 3KRXA 1EZTA 1FQJB 4PNKA 3CIKA 2OJ4A 2BCJA 4MK0A 3V5WA 2V4ZB 3C7KB 2IHBB 5HE0A 2JNUA 5DO9B 2EBZA 2AF0A 1CMZA 2IK8B 4EKDB 3C7LA 2CRPA 3PVUA 3NYOA 2D9JA 4TNDA 3UZTA 3PVWA
chains in the Genus database with same CATH superfamily
2IHDA 4HTEA 1AGRE 2BV1A 1EZYA 2OWIA 1FQIA 1EMUA 5HE1A 5HE3A 2DLVA 2BT2A 3PSCA 2JM5A 5HE2A 1DK8A 1OMWA 2GTPC 2ODEB 3KRWA 4TNBA 1FQKB 3NYNA 5REQB 3QYFA 3KRXA 1EZTA 1FQJB 4PNKA 3CIKA 2OJ4A 2BCJA 4MK0A 3V5WA 2V4ZB 3C7KB 3I5QA 2IHBB 5HE0A 2JNUA 5DO9B 2EBZA 2AF0A 1CMZA 2IK8B 4EKDB 3C7LA 2CRPA 3PVUA 3NYOA 2D9JA 4TNDA 3UZTA 3PVWA
chains in the Genus database with same CATH topology
2IHDA 1AGRE 2BV1A 1EZYA 2OWIA 1FQIA 1EMUA 5HE1A 5HE3A 2DLVA 2BT2A 3PSCA 2JM5A 5HE2A 1DK8A 1OMWA 2GTPC 2ODEB 3KRWA 4TNBA 1FQKB 3NYNA 5REQB 3QYFA 3KRXA 1EZTA 1FQJB 4PNKA 3CIKA 2OJ4A 2BCJA 4MK0A 3V5WA 2V4ZB 3C7KB 2IHBB 5HE0A 2JNUA 5DO9B 2EBZA 2AF0A 1CMZA 2IK8B 4EKDB 3C7LA 2CRPA 3PVUA 3NYOA 2D9JA 4TNDA 3UZTA 3PVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IHD A;  1AGR E;  2BV1 A;  1EZY A;  2OWI A;  1FQI A;  1EMU A;  5HE1 A;  5HE3 A;  2DLV A;  2BT2 A;  3PSC A;  2JM5 A;  5HE2 A;  1DK8 A;  1OMW A;  2GTP C;  2ODE B;  3KRW A;  4TNB A;  1FQK B;  3NYN A;  3KRX A;  1EZT A;  1FQJ B;  4PNK A;  3CIK A;  2OJ4 A;  2BCJ A;  4MK0 A;  3V5W A;  2V4Z B;  3C7K B;  2IHB B;  5HE0 A;  2JNU A;  5DO9 B;  2EBZ A;  2AF0 A;  1CMZ A;  2IK8 B;  4EKD B;  3C7L A;  2CRP A;  3PVU A;  3NYO A;  2D9J A;  4TND A;  3UZT A;  3PVW A; 
#chains in the Genus database with same CATH topology
 2IHD A;  4HTE A;  1AGR E;  2BV1 A;  1EZY A;  2OWI A;  1FQI A;  1EMU A;  5HE1 A;  5HE3 A;  2DLV A;  2BT2 A;  3PSC A;  2JM5 A;  5HE2 A;  1DK8 A;  1OMW A;  2GTP C;  2ODE B;  3KRW A;  4TNB A;  1FQK B;  3NYN A;  5REQ B;  3QYF A;  3KRX A;  1EZT A;  1FQJ B;  4PNK A;  3CIK A;  2OJ4 A;  2BCJ A;  4MK0 A;  3V5W A;  2V4Z B;  3C7K B;  3I5Q A;  2IHB B;  5HE0 A;  2JNU A;  5DO9 B;  2EBZ A;  2AF0 A;  1CMZ A;  2IK8 B;  4EKD B;  3C7L A;  2CRP A;  3PVU A;  3NYO A;  2D9J A;  4TND A;  3UZT A;  3PVW A; 
#chains in the Genus database with same CATH homology
 2IHD A;  1AGR E;  2BV1 A;  1EZY A;  2OWI A;  1FQI A;  1EMU A;  5HE1 A;  5HE3 A;  2DLV A;  2BT2 A;  3PSC A;  2JM5 A;  5HE2 A;  1DK8 A;  1OMW A;  2GTP C;  2ODE B;  3KRW A;  4TNB A;  1FQK B;  3NYN A;  5REQ B;  3QYF A;  3KRX A;  1EZT A;  1FQJ B;  4PNK A;  3CIK A;  2OJ4 A;  2BCJ A;  4MK0 A;  3V5W A;  2V4Z B;  3C7K B;  2IHB B;  5HE0 A;  2JNU A;  5DO9 B;  2EBZ A;  2AF0 A;  1CMZ A;  2IK8 B;  4EKD B;  3C7L A;  2CRP A;  3PVU A;  3NYO A;  2D9J A;  4TND A;  3UZT A;  3PVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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