1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
molecule tags Signaling protein
source organism Bos taurus
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
3NYNA 3PSCA 1DK8A 2ODEB 2BCJA 2BV1A 3CIKA 2JM5A 5DO9B 1AGRE 2BT2A 2D9JA 4TNDA 4EKDB 2JNUA 2V4ZB 2GTPC 3V5WA 2IHBB 1FQKB 5HE3A 5HE2A 4TNBA 2AF0A 2DLVA 2CRPA 1FQIA 5HE0A 3KRXA 1EZYA 2EBZA 2IHDA 1EZTA 2OJ4A 3PVUA 1CMZA 1FQJB 3NYOA 3PVWA 3UZTA 3C7KB 5HE1A 3C7LA 4PNKA 2IK8B 2OWIA 3KRWA 1OMWA 1EMUA 4MK0A
chains in the Genus database with same CATH superfamily
3NYNA 3PSCA 3QYFA 1DK8A 2ODEB 2BCJA 2BV1A 3CIKA 2JM5A 5DO9B 1AGRE 2BT2A 2D9JA 4TNDA 3I5QA 4EKDB 4HTEA 2JNUA 2V4ZB 2GTPC 3V5WA 2IHBB 1FQKB 5HE3A 5REQB 5HE2A 4TNBA 2AF0A 2DLVA 2CRPA 1FQIA 5HE0A 3KRXA 1EZYA 2EBZA 2IHDA 1EZTA 2OJ4A 3PVUA 1CMZA 1FQJB 3NYOA 3PVWA 3UZTA 3C7KB 5HE1A 3C7LA 4PNKA 2IK8B 2OWIA 3KRWA 1OMWA 1EMUA 4MK0A
chains in the Genus database with same CATH topology
3NYNA 3PSCA 3QYFA 1DK8A 2ODEB 2BCJA 2BV1A 3CIKA 2JM5A 5DO9B 1AGRE 2BT2A 2D9JA 4TNDA 4EKDB 2JNUA 2V4ZB 2GTPC 3V5WA 2IHBB 1FQKB 5HE3A 5REQB 5HE2A 4TNBA 2AF0A 2DLVA 2CRPA 1FQIA 5HE0A 3KRXA 1EZYA 2EBZA 2IHDA 1EZTA 2OJ4A 3PVUA 1CMZA 1FQJB 3NYOA 3PVWA 3UZTA 3C7KB 5HE1A 3C7LA 4PNKA 2IK8B 2OWIA 3KRWA 1OMWA 1EMUA 4MK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NYN A;  3PSC A;  1DK8 A;  2ODE B;  2BCJ A;  2BV1 A;  3CIK A;  2JM5 A;  5DO9 B;  1AGR E;  2BT2 A;  2D9J A;  4TND A;  4EKD B;  2JNU A;  2V4Z B;  2GTP C;  3V5W A;  2IHB B;  1FQK B;  5HE3 A;  5HE2 A;  4TNB A;  2AF0 A;  2DLV A;  2CRP A;  1FQI A;  5HE0 A;  3KRX A;  1EZY A;  2EBZ A;  2IHD A;  1EZT A;  2OJ4 A;  3PVU A;  1CMZ A;  1FQJ B;  3NYO A;  3PVW A;  3UZT A;  3C7K B;  5HE1 A;  3C7L A;  4PNK A;  2IK8 B;  2OWI A;  3KRW A;  1OMW A;  1EMU A;  4MK0 A; 
#chains in the Genus database with same CATH topology
 3NYN A;  3PSC A;  3QYF A;  1DK8 A;  2ODE B;  2BCJ A;  2BV1 A;  3CIK A;  2JM5 A;  5DO9 B;  1AGR E;  2BT2 A;  2D9J A;  4TND A;  3I5Q A;  4EKD B;  4HTE A;  2JNU A;  2V4Z B;  2GTP C;  3V5W A;  2IHB B;  1FQK B;  5HE3 A;  5REQ B;  5HE2 A;  4TNB A;  2AF0 A;  2DLV A;  2CRP A;  1FQI A;  5HE0 A;  3KRX A;  1EZY A;  2EBZ A;  2IHD A;  1EZT A;  2OJ4 A;  3PVU A;  1CMZ A;  1FQJ B;  3NYO A;  3PVW A;  3UZT A;  3C7K B;  5HE1 A;  3C7L A;  4PNK A;  2IK8 B;  2OWI A;  3KRW A;  1OMW A;  1EMU A;  4MK0 A; 
#chains in the Genus database with same CATH homology
 3NYN A;  3PSC A;  3QYF A;  1DK8 A;  2ODE B;  2BCJ A;  2BV1 A;  3CIK A;  2JM5 A;  5DO9 B;  1AGR E;  2BT2 A;  2D9J A;  4TND A;  4EKD B;  2JNU A;  2V4Z B;  2GTP C;  3V5W A;  2IHB B;  1FQK B;  5HE3 A;  5REQ B;  5HE2 A;  4TNB A;  2AF0 A;  2DLV A;  2CRP A;  1FQI A;  5HE0 A;  3KRX A;  1EZY A;  2EBZ A;  2IHD A;  1EZT A;  2OJ4 A;  3PVU A;  1CMZ A;  1FQJ B;  3NYO A;  3PVW A;  3UZT A;  3C7K B;  5HE1 A;  3C7L A;  4PNK A;  2IK8 B;  2OWI A;  3KRW A;  1OMW A;  1EMU A;  4MK0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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