1FQKB

Crystal structure of the heterodimeric complex of the rgs domain of rgs9, and the gt/i1 chimera alpha subunit [(rgs9)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
136
structure length
136
Chain Sequence
LVDIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
molecule tags Signaling protein
source organism Bos taurus
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
total genus 49
structure length 136
sequence length 136
chains with identical sequence D
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqkB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqkB01
4TNBA 5HE1A 5HE2A 2CRPA 1FQIA 1EMUA 5HE3A 3C7LA 1CMZA 2GTPC 2JM5A 2OWIA 4MK0A 1EZYA 2EBZA 2IK8B 1FQJB 3CIKA 3KRXA 2IHBB 3NYOA 5HE0A 2BV1A 2IHDA 2BCJA 3UZTA 3KRWA 3V5WA 3PVUA 3PSCA 1OMWA 3PVWA 2BT2A 2DLVA 2AF0A 3C7KB 4PNKA 1FQKB 1EZTA 2ODEB 2V4ZB 2JNUA 3NYNA 2D9JA 2OJ4A 4TNDA 4EKDB 1DK8A 5DO9B 1AGRE
chains in the Genus database with same CATH superfamily
4TNBA 5HE1A 5HE2A 2CRPA 1FQIA 3QYFA 1EMUA 5HE3A 3C7LA 1CMZA 2GTPC 2JM5A 2OWIA 4MK0A 1EZYA 2EBZA 3I5QA 2IK8B 1FQJB 3CIKA 3KRXA 2IHBB 3NYOA 5HE0A 5REQB 2BV1A 2IHDA 2BCJA 3UZTA 3KRWA 3V5WA 3PVUA 3PSCA 1OMWA 3PVWA 2BT2A 2DLVA 2AF0A 3C7KB 4PNKA 1FQKB 1EZTA 2ODEB 2V4ZB 2JNUA 3NYNA 2D9JA 2OJ4A 4TNDA 4EKDB 4HTEA 1DK8A 5DO9B 1AGRE
chains in the Genus database with same CATH topology
4TNBA 5HE1A 5HE2A 2CRPA 1FQIA 3QYFA 1EMUA 5HE3A 3C7LA 1CMZA 2GTPC 2JM5A 2OWIA 4MK0A 1EZYA 2EBZA 2IK8B 1FQJB 3CIKA 3KRXA 2IHBB 3NYOA 5HE0A 5REQB 2BV1A 2IHDA 2BCJA 3UZTA 3KRWA 3V5WA 3PVUA 3PSCA 1OMWA 3PVWA 2BT2A 2DLVA 2AF0A 3C7KB 4PNKA 1FQKB 1EZTA 2ODEB 2V4ZB 2JNUA 3NYNA 2D9JA 2OJ4A 4TNDA 4EKDB 1DK8A 5DO9B 1AGRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TNB A;  5HE1 A;  5HE2 A;  2CRP A;  1FQI A;  1EMU A;  5HE3 A;  3C7L A;  1CMZ A;  2GTP C;  2JM5 A;  2OWI A;  4MK0 A;  1EZY A;  2EBZ A;  2IK8 B;  1FQJ B;  3CIK A;  3KRX A;  2IHB B;  3NYO A;  5HE0 A;  2BV1 A;  2IHD A;  2BCJ A;  3UZT A;  3KRW A;  3V5W A;  3PVU A;  3PSC A;  1OMW A;  3PVW A;  2BT2 A;  2DLV A;  2AF0 A;  3C7K B;  4PNK A;  1FQK B;  1EZT A;  2ODE B;  2V4Z B;  2JNU A;  3NYN A;  2D9J A;  2OJ4 A;  4TND A;  4EKD B;  1DK8 A;  5DO9 B;  1AGR E; 
#chains in the Genus database with same CATH topology
 4TNB A;  5HE1 A;  5HE2 A;  2CRP A;  1FQI A;  3QYF A;  1EMU A;  5HE3 A;  3C7L A;  1CMZ A;  2GTP C;  2JM5 A;  2OWI A;  4MK0 A;  1EZY A;  2EBZ A;  3I5Q A;  2IK8 B;  1FQJ B;  3CIK A;  3KRX A;  2IHB B;  3NYO A;  5HE0 A;  5REQ B;  2BV1 A;  2IHD A;  2BCJ A;  3UZT A;  3KRW A;  3V5W A;  3PVU A;  3PSC A;  1OMW A;  3PVW A;  2BT2 A;  2DLV A;  2AF0 A;  3C7K B;  4PNK A;  1FQK B;  1EZT A;  2ODE B;  2V4Z B;  2JNU A;  3NYN A;  2D9J A;  2OJ4 A;  4TND A;  4EKD B;  4HTE A;  1DK8 A;  5DO9 B;  1AGR E; 
#chains in the Genus database with same CATH homology
 4TNB A;  5HE1 A;  5HE2 A;  2CRP A;  1FQI A;  3QYF A;  1EMU A;  5HE3 A;  3C7L A;  1CMZ A;  2GTP C;  2JM5 A;  2OWI A;  4MK0 A;  1EZY A;  2EBZ A;  2IK8 B;  1FQJ B;  3CIK A;  3KRX A;  2IHB B;  3NYO A;  5HE0 A;  5REQ B;  2BV1 A;  2IHD A;  2BCJ A;  3UZT A;  3KRW A;  3V5W A;  3PVU A;  3PSC A;  1OMW A;  3PVW A;  2BT2 A;  2DLV A;  2AF0 A;  3C7K B;  4PNK A;  1FQK B;  1EZT A;  2ODE B;  2V4Z B;  2JNU A;  3NYN A;  2D9J A;  2OJ4 A;  4TND A;  4EKD B;  1DK8 A;  5DO9 B;  1AGR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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