1FWQA

Solution structure of human mss4, a guanine nucleotide exchange factor for rab proteins
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
115
structure length
115
Chain Sequence
ELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Metal binding protein
source organism Homo sapiens
publication title Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface.
pubmed doi rcsb
molecule keywords GUANINE NUCLEOTIDE EXCHANGE FACTOR
total genus 13
structure length 115
sequence length 115
ec nomenclature
pdb deposition date 2000-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04421 Mss4 Mss4 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.10 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 1fwqA00
2LOYA 2FU5A 2HR9A 3EBMA 1HXRA 1TXJA 3P3KA 1H7YA 1FWQA 2KWBA 1H6QA 1YZ1A
chains in the Genus database with same CATH superfamily
3ZD6A 2FU5A 3OG8A 4TZ4C 3LRRA 1HXRA 3HCHA 5E3HA 3NCUA 2QFDA 1H6QA 3HCGA 2LOYA 2YKGA 2K8DA 3HCIA 3WX2A 2KV1A 1TXJA 1H7YA 3DJMA 4V30A 3CEZA 3HCJA 4V2ZA 2KWBA 5AMHA 4A2VA 4AY2A 4V31A 1YZ1A 3GA3A 3MAOA 5F98A 4CI3B 4CI1B 3EBMA 5F9FA 3P3KA 4V2YA 1FWQA 2RMJA 2RQBA 3CXKA 4BPBA 4CI2B 4TZUA 3WX1A 2HR9A 2KZNA 3LRNA 1L1DA 3EQTA 2LVLA 3E0MA 2RQAA 4TZCA 5F9HA 4A2XA 3E0OA 2QFBA 3FACA 2W4RA 3ZD7A
chains in the Genus database with same CATH topology
3ZD6A 2FU5A 3OG8A 3LRRA 1HXRA 5E3HA 3NCUA 2QFDA 1H6QA 2LOYA 2YKGA 1TXJA 1H7YA 3DJMA 4A2VA 4AY2A 2KWBA 1YZ1A 3GA3A 5F98A 3EBMA 5F9FA 3P3KA 1FWQA 2RMJA 2RQBA 4BPBA 2HR9A 3EQTA 3LRNA 2LVLA 5F9HA 2RQAA 4A2XA 2QFBA 3FACA 2W4RA 3ZD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LOY A;  2FU5 A;  2HR9 A;  3EBM A;  1HXR A;  1TXJ A;  3P3K A;  1H7Y A;  1FWQ A;  2KWB A;  1H6Q A;  1YZ1 A; 
#chains in the Genus database with same CATH topology
 3ZD6 A;  2FU5 A;  3OG8 A;  4TZ4 C;  3LRR A;  1HXR A;  3HCH A;  5E3H A;  3NCU A;  2QFD A;  1H6Q A;  3HCG A;  2LOY A;  2YKG A;  2K8D A;  3HCI A;  3WX2 A;  2KV1 A;  1TXJ A;  1H7Y A;  3DJM A;  4V30 A;  3CEZ A;  3HCJ A;  4V2Z A;  2KWB A;  5AMH A;  4A2V A;  4AY2 A;  4V31 A;  1YZ1 A;  3GA3 A;  3MAO A;  5F98 A;  4CI3 B;  4CI1 B;  3EBM A;  5F9F A;  3P3K A;  4V2Y A;  1FWQ A;  2RMJ A;  2RQB A;  3CXK A;  4BPB A;  4CI2 B;  4TZU A;  3WX1 A;  2HR9 A;  2KZN A;  3LRN A;  1L1D A;  3EQT A;  2LVL A;  3E0M A;  2RQA A;  4TZC A;  5F9H A;  4A2X A;  3E0O A;  2QFB A;  3FAC A;  2W4R A;  3ZD7 A; 
#chains in the Genus database with same CATH homology
 3ZD6 A;  2FU5 A;  3OG8 A;  3LRR A;  1HXR A;  5E3H A;  3NCU A;  2QFD A;  1H6Q A;  2LOY A;  2YKG A;  1TXJ A;  1H7Y A;  3DJM A;  4A2V A;  4AY2 A;  2KWB A;  1YZ1 A;  3GA3 A;  5F98 A;  3EBM A;  5F9F A;  3P3K A;  1FWQ A;  2RMJ A;  2RQB A;  4BPB A;  2HR9 A;  3EQT A;  3LRN A;  2LVL A;  5F9H A;  2RQA A;  4A2X A;  2QFB A;  3FAC A;  2W4R A;  3ZD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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