1FWQA

Solution structure of human mss4, a guanine nucleotide exchange factor for rab proteins
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
115
structure length
115
Chain Sequence
ELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords GUANINE NUCLEOTIDE EXCHANGE FACTOR
total genus 13
structure length 115
sequence length 115
ec nomenclature
pdb deposition date 2000-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04421 Mss4 Mss4 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.10 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 1fwqA00
1HXRA 3P3KA 3EBMA 1H6QA 2LOYA 1YZ1A 1FWQA 2KWBA 2FU5A 1TXJA 2HR9A 1H7YA
chains in the Genus database with same CATH superfamily
5AMHA 4TZUA 2YKGA 3CXKA 2KZNA 3MAOA 3P3KA 4AY2A 3CEZA 1H6QA 4V2ZA 4CI1B 2QFBA 1FWQA 4CI2B 3HCGA 3GA3A 3ZD7A 5F98A 3HCIA 4A2VA 3HCJA 3E0MA 1YZ1A 2RQAA 4TZCA 3WX1A 2FU5A 4CI3B 3HCHA 2QFDA 2KWBA 2LVLA 2W4RA 3WX2A 5F9FA 2RMJA 2RQBA 2K8DA 5E3HA 4A2XA 2KV1A 3EBMA 2HR9A 3LRNA 3E0OA 4BPBA 3LRRA 3OG8A 3DJMA 1HXRA 3NCUA 3EQTA 4V30A 2LOYA 3ZD6A 4TZ4C 5F9HA 4V2YA 4V31A 3FACA 1TXJA 1L1DA 1H7YA
chains in the Genus database with same CATH topology
2YKGA 3P3KA 4AY2A 1H6QA 2QFBA 1FWQA 3GA3A 3ZD7A 5F98A 4A2VA 1YZ1A 2RQAA 2FU5A 2QFDA 2KWBA 2LVLA 2W4RA 5F9FA 2RMJA 2RQBA 5E3HA 4A2XA 3EBMA 2HR9A 3LRNA 4BPBA 3LRRA 3OG8A 3DJMA 1HXRA 3NCUA 3EQTA 2LOYA 3ZD6A 5F9HA 3FACA 1TXJA 1H7YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HXR A;  3P3K A;  3EBM A;  1H6Q A;  2LOY A;  1YZ1 A;  1FWQ A;  2KWB A;  2FU5 A;  1TXJ A;  2HR9 A;  1H7Y A; 
#chains in the Genus database with same CATH topology
 5AMH A;  4TZU A;  2YKG A;  3CXK A;  2KZN A;  3MAO A;  3P3K A;  4AY2 A;  3CEZ A;  1H6Q A;  4V2Z A;  4CI1 B;  2QFB A;  1FWQ A;  4CI2 B;  3HCG A;  3GA3 A;  3ZD7 A;  5F98 A;  3HCI A;  4A2V A;  3HCJ A;  3E0M A;  1YZ1 A;  2RQA A;  4TZC A;  3WX1 A;  2FU5 A;  4CI3 B;  3HCH A;  2QFD A;  2KWB A;  2LVL A;  2W4R A;  3WX2 A;  5F9F A;  2RMJ A;  2RQB A;  2K8D A;  5E3H A;  4A2X A;  2KV1 A;  3EBM A;  2HR9 A;  3LRN A;  3E0O A;  4BPB A;  3LRR A;  3OG8 A;  3DJM A;  1HXR A;  3NCU A;  3EQT A;  4V30 A;  2LOY A;  3ZD6 A;  4TZ4 C;  5F9H A;  4V2Y A;  4V31 A;  3FAC A;  1TXJ A;  1L1D A;  1H7Y A; 
#chains in the Genus database with same CATH homology
 2YKG A;  3P3K A;  4AY2 A;  1H6Q A;  2QFB A;  1FWQ A;  3GA3 A;  3ZD7 A;  5F98 A;  4A2V A;  1YZ1 A;  2RQA A;  2FU5 A;  2QFD A;  2KWB A;  2LVL A;  2W4R A;  5F9F A;  2RMJ A;  2RQB A;  5E3H A;  4A2X A;  3EBM A;  2HR9 A;  3LRN A;  4BPB A;  3LRR A;  3OG8 A;  3DJM A;  1HXR A;  3NCU A;  3EQT A;  2LOY A;  3ZD6 A;  5F9H A;  3FAC A;  1TXJ A;  1H7Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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