1N45A

X-ray crystal structure of human heme oxygenase-1 (ho-1) in complex with its substrate heme
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
214
structure length
214
Chain Sequence
PQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords heme oxygenase 1
total genus 82
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2002-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1n45A00
1XK3A 1XK2A 1WNVA 1UDDA 3IBXA 1RCWA 4WMHA 3HNHA 3TGMA 4GPHA 1WNXA 1TO9A 1P3UA 4NY7A 1WNWA 3MOOA 3RM5A 1OTVA 1ULXA 1OZLA 4G8PA 1WZDA 1OYKA 1SK7A 2ZVUA 3BJDA 4G7PA 1XK0A 2DY5A 3NO6A 1XK1A 4GPFA 3HMLA 4WWZA 1IW1A 4FN6A 5BTQA 1J77A 1IX3A 1RTWA 2A2OA 1J2CA 4WX0A 1J02A 4MECA 1TWNA 4G99A 3HLXA 1IRMA 1TWRA 4GPCA 1WZGA 3CZYA 1N45A 1N3UA 1WOVA 2GM7A 1T5PA 4WWJA 4LQXA 4G7TA 1DVGA 1IX4A 1OTWA 3I9TA 2Q4XA 2F2GA 1P3TA 3I8RA 3DDEA 2QPPA 1WOXA 1P3VA 1WWMA 1WE1A 1OZRA 2QZCA 2QCXA 1NI6A 1S8CA 1OYLA 4G7LA 1UBBA 4G7UA 1DVEA 3MVUA 1IW0A 1XJZA 2E7EA 2A6BA 1OZEA 2Q32A 4G8UA 1WZFA 1WOWA 3OQLA 3B5PA 1TYHA 4G8WA 2RGZA 1YAFA 1IVJA 1S13A 1VGIA 2RD3A 2A2MA 3HOKA 1TO9B 3I9UA 4GOHA 1OZWA 3B5OA 4WD4A 4G98A 4RAJA 1Z72A 1YAKA 2Z68A 1V8XA 3K4FA 2GM8A
chains in the Genus database with same CATH superfamily
1XK3A 1XK2A 1WNVA 1UDDA 3IBXA 1RCWA 4WMHA 3HNHA 3TGMA 4GPHA 1WNXA 1TO9A 1P3UA 4NY7A 1WNWA 3MOOA 3RM5A 1OTVA 1ULXA 1OZLA 4G8PA 1WZDA 1OYKA 1SK7A 2ZVUA 3BJDA 4G7PA 1XK0A 2DY5A 3NO6A 1XK1A 4GPFA 3HMLA 4WWZA 1IW1A 4FN6A 5BTQA 1J77A 1IX3A 1RTWA 2A2OA 1J2CA 4WX0A 1J02A 4MECA 1TWNA 4G99A 3HLXA 1IRMA 1TWRA 4GPCA 1WZGA 3CZYA 1N45A 1N3UA 1WOVA 2GM7A 1T5PA 4WWJA 4LQXA 4G7TA 1DVGA 1IX4A 1OTWA 3I9TA 2Q4XA 2F2GA 1P3TA 3I8RA 3DDEA 2QPPA 1WOXA 1P3VA 1WWMA 1WE1A 1OZRA 2QZCA 2QCXA 1NI6A 1S8CA 1OYLA 4G7LA 1UBBA 4G7UA 1DVEA 3MVUA 1IW0A 1XJZA 2E7EA 2A6BA 1OZEA 2Q32A 2LCUA 4G8UA 1WZFA 1WOWA 3OQLA 3B5PA 1TYHA 4G8WA 2RGZA 1YAFA 1IVJA 1S13A 1VGIA 2RD3A 2A2MA 3HOKA 1TO9B 3I9UA 4GOHA 1OZWA 3B5OA 4WD4A 4G98A 4RAJA 1Z72A 1YAKA 2Z68A 1V8XA 3K4FA 2GM8A
chains in the Genus database with same CATH topology
1XK3A 1XK2A 1WNVA 1UDDA 3IBXA 1RCWA 4WMHA 3HNHA 3TGMA 4GPHA 1WNXA 1TO9A 1P3UA 4NY7A 1WNWA 3MOOA 3RM5A 1OTVA 1ULXA 1OZLA 4G8PA 1WZDA 1OYKA 1SK7A 2ZVUA 3BJDA 4G7PA 1XK0A 2DY5A 3NO6A 1XK1A 4GPFA 3HMLA 4WWZA 1IW1A 4FN6A 5BTQA 1J77A 1IX3A 1RTWA 2A2OA 1J2CA 4WX0A 1J02A 4MECA 1TWNA 4G99A 3HLXA 1IRMA 1TWRA 4GPCA 1WZGA 3CZYA 1N45A 1N3UA 1WOVA 2GM7A 1T5PA 4WWJA 4LQXA 4G7TA 1DVGA 1IX4A 1OTWA 3I9TA 2Q4XA 2F2GA 1P3TA 3I8RA 3DDEA 2QPPA 1WOXA 1P3VA 1WWMA 1WE1A 1OZRA 2QZCA 2QCXA 1NI6A 1S8CA 1OYLA 4G7LA 1UBBA 4G7UA 1DVEA 3MVUA 1IW0A 1XJZA 2E7EA 2A6BA 1OZEA 2Q32A 4G8UA 1WZFA 1WOWA 3OQLA 3B5PA 1TYHA 4G8WA 2RGZA 1YAFA 1IVJA 1S13A 1VGIA 2RD3A 2A2MA 3HOKA 1TO9B 3I9UA 4GOHA 1OZWA 3B5OA 4WD4A 4G98A 4RAJA 1Z72A 1YAKA 2Z68A 1V8XA 3K4FA 2GM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XK3 A;  1XK2 A;  1WNV A;  1UDD A;  3IBX A;  1RCW A;  4WMH A;  3HNH A;  3TGM A;  4GPH A;  1WNX A;  1TO9 A;  1P3U A;  4NY7 A;  1WNW A;  3MOO A;  3RM5 A;  1OTV A;  1ULX A;  1OZL A;  4G8P A;  1WZD A;  1OYK A;  1SK7 A;  2ZVU A;  3BJD A;  4G7P A;  1XK0 A;  2DY5 A;  3NO6 A;  1XK1 A;  4GPF A;  3HML A;  4WWZ A;  1IW1 A;  4FN6 A;  5BTQ A;  1J77 A;  1IX3 A;  1RTW A;  2A2O A;  1J2C A;  4WX0 A;  1J02 A;  4MEC A;  1TWN A;  4G99 A;  3HLX A;  1IRM A;  1TWR A;  4GPC A;  1WZG A;  3CZY A;  1N45 A;  1N3U A;  1WOV A;  2GM7 A;  1T5P A;  4WWJ A;  4LQX A;  4G7T A;  1DVG A;  1IX4 A;  1OTW A;  3I9T A;  2Q4X A;  2F2G A;  1P3T A;  3I8R A;  3DDE A;  2QPP A;  1WOX A;  1P3V A;  1WWM A;  1WE1 A;  1OZR A;  2QZC A;  2QCX A;  1NI6 A;  1S8C A;  1OYL A;  4G7L A;  1UBB A;  4G7U A;  1DVE A;  3MVU A;  1IW0 A;  1XJZ A;  2E7E A;  2A6B A;  1OZE A;  2Q32 A;  4G8U A;  1WZF A;  1WOW A;  3OQL A;  3B5P A;  1TYH A;  4G8W A;  2RGZ A;  1YAF A;  1IVJ A;  1S13 A;  1VGI A;  2RD3 A;  2A2M A;  3HOK A;  1TO9 B;  3I9U A;  4GOH A;  1OZW A;  3B5O A;  4WD4 A;  4G98 A;  4RAJ A;  1Z72 A;  1YAK A;  2Z68 A;  1V8X A;  3K4F A;  2GM8 A; 
#chains in the Genus database with same CATH topology
 1XK3 A;  1XK2 A;  1WNV A;  1UDD A;  3IBX A;  1RCW A;  4WMH A;  3HNH A;  3TGM A;  4GPH A;  1WNX A;  1TO9 A;  1P3U A;  4NY7 A;  1WNW A;  3MOO A;  3RM5 A;  1OTV A;  1ULX A;  1OZL A;  4G8P A;  1WZD A;  1OYK A;  1SK7 A;  2ZVU A;  3BJD A;  4G7P A;  1XK0 A;  2DY5 A;  3NO6 A;  1XK1 A;  4GPF A;  3HML A;  4WWZ A;  1IW1 A;  4FN6 A;  5BTQ A;  1J77 A;  1IX3 A;  1RTW A;  2A2O A;  1J2C A;  4WX0 A;  1J02 A;  4MEC A;  1TWN A;  4G99 A;  3HLX A;  1IRM A;  1TWR A;  4GPC A;  1WZG A;  3CZY A;  1N45 A;  1N3U A;  1WOV A;  2GM7 A;  1T5P A;  4WWJ A;  4LQX A;  4G7T A;  1DVG A;  1IX4 A;  1OTW A;  3I9T A;  2Q4X A;  2F2G A;  1P3T A;  3I8R A;  3DDE A;  2QPP A;  1WOX A;  1P3V A;  1WWM A;  1WE1 A;  1OZR A;  2QZC A;  2QCX A;  1NI6 A;  1S8C A;  1OYL A;  4G7L A;  1UBB A;  4G7U A;  1DVE A;  3MVU A;  1IW0 A;  1XJZ A;  2E7E A;  2A6B A;  1OZE A;  2Q32 A;  2LCU A;  4G8U A;  1WZF A;  1WOW A;  3OQL A;  3B5P A;  1TYH A;  4G8W A;  2RGZ A;  1YAF A;  1IVJ A;  1S13 A;  1VGI A;  2RD3 A;  2A2M A;  3HOK A;  1TO9 B;  3I9U A;  4GOH A;  1OZW A;  3B5O A;  4WD4 A;  4G98 A;  4RAJ A;  1Z72 A;  1YAK A;  2Z68 A;  1V8X A;  3K4F A;  2GM8 A; 
#chains in the Genus database with same CATH homology
 1XK3 A;  1XK2 A;  1WNV A;  1UDD A;  3IBX A;  1RCW A;  4WMH A;  3HNH A;  3TGM A;  4GPH A;  1WNX A;  1TO9 A;  1P3U A;  4NY7 A;  1WNW A;  3MOO A;  3RM5 A;  1OTV A;  1ULX A;  1OZL A;  4G8P A;  1WZD A;  1OYK A;  1SK7 A;  2ZVU A;  3BJD A;  4G7P A;  1XK0 A;  2DY5 A;  3NO6 A;  1XK1 A;  4GPF A;  3HML A;  4WWZ A;  1IW1 A;  4FN6 A;  5BTQ A;  1J77 A;  1IX3 A;  1RTW A;  2A2O A;  1J2C A;  4WX0 A;  1J02 A;  4MEC A;  1TWN A;  4G99 A;  3HLX A;  1IRM A;  1TWR A;  4GPC A;  1WZG A;  3CZY A;  1N45 A;  1N3U A;  1WOV A;  2GM7 A;  1T5P A;  4WWJ A;  4LQX A;  4G7T A;  1DVG A;  1IX4 A;  1OTW A;  3I9T A;  2Q4X A;  2F2G A;  1P3T A;  3I8R A;  3DDE A;  2QPP A;  1WOX A;  1P3V A;  1WWM A;  1WE1 A;  1OZR A;  2QZC A;  2QCX A;  1NI6 A;  1S8C A;  1OYL A;  4G7L A;  1UBB A;  4G7U A;  1DVE A;  3MVU A;  1IW0 A;  1XJZ A;  2E7E A;  2A6B A;  1OZE A;  2Q32 A;  4G8U A;  1WZF A;  1WOW A;  3OQL A;  3B5P A;  1TYH A;  4G8W A;  2RGZ A;  1YAF A;  1IVJ A;  1S13 A;  1VGI A;  2RD3 A;  2A2M A;  3HOK A;  1TO9 B;  3I9U A;  4GOH A;  1OZW A;  3B5O A;  4WD4 A;  4G98 A;  4RAJ A;  1Z72 A;  1YAK A;  2Z68 A;  1V8X A;  3K4F A;  2GM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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