1OYKA

Crystal structures of the ferric, ferrous, and ferrous-no forms of the asp140ala mutant of human heme oxygenase-1: catalytic implications
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
214
structure length
214
Chain Sequence
PQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGALSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Heme oxygenase 1
total genus 82
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2003-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1oykA00
3DDEA 1V8XA 2GM7A 1IW0A 4G7UA 2E7EA 2A6BA 4RAJA 1WZFA 2QCXA 1IRMA 4G7PA 1Z72A 3I9UA 4G99A 4GPCA 4G8UA 1TWRA 1WOWA 1WZDA 1XK0A 1N3UA 4MECA 3NO6A 1WWMA 1OZEA 1YAKA 1IVJA 1OTWA 4FN6A 4GPFA 3CZYA 4NY7A 4G8PA 1UDDA 2RD3A 1J77A 4G8WA 1WNVA 1S13A 2GM8A 1YAFA 1UBBA 3HOKA 3HMLA 1OZRA 3OQLA 3BJDA 1OZLA 1J2CA 3RM5A 1WOXA 1P3VA 2QZCA 2QPPA 2F2GA 1XK3A 1TWNA 4G7LA 1P3TA 3B5PA 3I9TA 1DVGA 4WMHA 1NI6A 1WZGA 1OYLA 1SK7A 5BTQA 3I8RA 4WWZA 3MOOA 3TGMA 1WE1A 4GPHA 2Q32A 1TO9A 1DVEA 1OYKA 1VGIA 2DY5A 2Q4XA 4WX0A 1N45A 1TYHA 2Z68A 3MVUA 3K4FA 1RTWA 1ULXA 1S8CA 4G98A 1IX3A 4LQXA 1OZWA 4WD4A 1P3UA 1IX4A 1OTVA 1WNXA 1T5PA 1J02A 1XK2A 2A2MA 1TO9B 1IW1A 1RCWA 4GOHA 4WWJA 3HLXA 1XJZA 1WOVA 2RGZA 2ZVUA 1XK1A 4G7TA 3IBXA 3B5OA 2A2OA 3HNHA 1WNWA
chains in the Genus database with same CATH superfamily
3DDEA 1V8XA 2GM7A 1IW0A 4G7UA 2E7EA 2A6BA 4RAJA 1WZFA 2QCXA 1IRMA 4G7PA 1Z72A 2LCUA 3I9UA 4G99A 4GPCA 4G8UA 1TWRA 1WOWA 1WZDA 1XK0A 1N3UA 4MECA 3NO6A 1WWMA 1OZEA 1YAKA 1IVJA 1OTWA 4FN6A 4GPFA 3CZYA 4NY7A 4G8PA 1UDDA 2RD3A 1J77A 4G8WA 1WNVA 1S13A 2GM8A 1YAFA 1UBBA 3HOKA 3HMLA 1OZRA 3OQLA 3BJDA 1OZLA 1J2CA 3RM5A 1WOXA 1P3VA 2QZCA 2QPPA 2F2GA 1XK3A 1TWNA 4G7LA 1P3TA 3B5PA 3I9TA 1DVGA 4WMHA 1NI6A 1WZGA 1OYLA 1SK7A 5BTQA 3I8RA 4WWZA 3MOOA 3TGMA 1WE1A 4GPHA 2Q32A 1TO9A 1DVEA 1OYKA 1VGIA 2DY5A 2Q4XA 4WX0A 1N45A 1TYHA 2Z68A 3MVUA 3K4FA 1RTWA 1ULXA 1S8CA 4G98A 1IX3A 4LQXA 1OZWA 4WD4A 1P3UA 1IX4A 1OTVA 1WNXA 1T5PA 1J02A 1XK2A 2A2MA 1TO9B 1IW1A 1RCWA 4GOHA 4WWJA 3HLXA 1XJZA 1WOVA 2RGZA 2ZVUA 1XK1A 4G7TA 3IBXA 3B5OA 2A2OA 3HNHA 1WNWA
chains in the Genus database with same CATH topology
3DDEA 1V8XA 2GM7A 1IW0A 4G7UA 2E7EA 2A6BA 4RAJA 1WZFA 2QCXA 1IRMA 4G7PA 1Z72A 3I9UA 4G99A 4GPCA 4G8UA 1TWRA 1WOWA 1WZDA 1XK0A 1N3UA 4MECA 3NO6A 1WWMA 1OZEA 1YAKA 1IVJA 1OTWA 4FN6A 4GPFA 3CZYA 4NY7A 4G8PA 1UDDA 2RD3A 1J77A 4G8WA 1WNVA 1S13A 2GM8A 1YAFA 1UBBA 3HOKA 3HMLA 1OZRA 3OQLA 3BJDA 1OZLA 1J2CA 3RM5A 1WOXA 1P3VA 2QZCA 2QPPA 2F2GA 1XK3A 1TWNA 4G7LA 1P3TA 3B5PA 3I9TA 1DVGA 4WMHA 1NI6A 1WZGA 1OYLA 1SK7A 5BTQA 3I8RA 4WWZA 3MOOA 3TGMA 1WE1A 4GPHA 2Q32A 1TO9A 1DVEA 1OYKA 1VGIA 2DY5A 2Q4XA 4WX0A 1N45A 1TYHA 2Z68A 3MVUA 3K4FA 1RTWA 1ULXA 1S8CA 4G98A 1IX3A 4LQXA 1OZWA 4WD4A 1P3UA 1IX4A 1OTVA 1WNXA 1T5PA 1J02A 1XK2A 2A2MA 1TO9B 1IW1A 1RCWA 4GOHA 4WWJA 3HLXA 1XJZA 1WOVA 2RGZA 2ZVUA 1XK1A 4G7TA 3IBXA 3B5OA 2A2OA 3HNHA 1WNWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DDE A;  1V8X A;  2GM7 A;  1IW0 A;  4G7U A;  2E7E A;  2A6B A;  4RAJ A;  1WZF A;  2QCX A;  1IRM A;  4G7P A;  1Z72 A;  3I9U A;  4G99 A;  4GPC A;  4G8U A;  1TWR A;  1WOW A;  1WZD A;  1XK0 A;  1N3U A;  4MEC A;  3NO6 A;  1WWM A;  1OZE A;  1YAK A;  1IVJ A;  1OTW A;  4FN6 A;  4GPF A;  3CZY A;  4NY7 A;  4G8P A;  1UDD A;  2RD3 A;  1J77 A;  4G8W A;  1WNV A;  1S13 A;  2GM8 A;  1YAF A;  1UBB A;  3HOK A;  3HML A;  1OZR A;  3OQL A;  3BJD A;  1OZL A;  1J2C A;  3RM5 A;  1WOX A;  1P3V A;  2QZC A;  2QPP A;  2F2G A;  1XK3 A;  1TWN A;  4G7L A;  1P3T A;  3B5P A;  3I9T A;  1DVG A;  4WMH A;  1NI6 A;  1WZG A;  1OYL A;  1SK7 A;  5BTQ A;  3I8R A;  4WWZ A;  3MOO A;  3TGM A;  1WE1 A;  4GPH A;  2Q32 A;  1TO9 A;  1DVE A;  1OYK A;  1VGI A;  2DY5 A;  2Q4X A;  4WX0 A;  1N45 A;  1TYH A;  2Z68 A;  3MVU A;  3K4F A;  1RTW A;  1ULX A;  1S8C A;  4G98 A;  1IX3 A;  4LQX A;  1OZW A;  4WD4 A;  1P3U A;  1IX4 A;  1OTV A;  1WNX A;  1T5P A;  1J02 A;  1XK2 A;  2A2M A;  1TO9 B;  1IW1 A;  1RCW A;  4GOH A;  4WWJ A;  3HLX A;  1XJZ A;  1WOV A;  2RGZ A;  2ZVU A;  1XK1 A;  4G7T A;  3IBX A;  3B5O A;  2A2O A;  3HNH A;  1WNW A; 
#chains in the Genus database with same CATH topology
 3DDE A;  1V8X A;  2GM7 A;  1IW0 A;  4G7U A;  2E7E A;  2A6B A;  4RAJ A;  1WZF A;  2QCX A;  1IRM A;  4G7P A;  1Z72 A;  2LCU A;  3I9U A;  4G99 A;  4GPC A;  4G8U A;  1TWR A;  1WOW A;  1WZD A;  1XK0 A;  1N3U A;  4MEC A;  3NO6 A;  1WWM A;  1OZE A;  1YAK A;  1IVJ A;  1OTW A;  4FN6 A;  4GPF A;  3CZY A;  4NY7 A;  4G8P A;  1UDD A;  2RD3 A;  1J77 A;  4G8W A;  1WNV A;  1S13 A;  2GM8 A;  1YAF A;  1UBB A;  3HOK A;  3HML A;  1OZR A;  3OQL A;  3BJD A;  1OZL A;  1J2C A;  3RM5 A;  1WOX A;  1P3V A;  2QZC A;  2QPP A;  2F2G A;  1XK3 A;  1TWN A;  4G7L A;  1P3T A;  3B5P A;  3I9T A;  1DVG A;  4WMH A;  1NI6 A;  1WZG A;  1OYL A;  1SK7 A;  5BTQ A;  3I8R A;  4WWZ A;  3MOO A;  3TGM A;  1WE1 A;  4GPH A;  2Q32 A;  1TO9 A;  1DVE A;  1OYK A;  1VGI A;  2DY5 A;  2Q4X A;  4WX0 A;  1N45 A;  1TYH A;  2Z68 A;  3MVU A;  3K4F A;  1RTW A;  1ULX A;  1S8C A;  4G98 A;  1IX3 A;  4LQX A;  1OZW A;  4WD4 A;  1P3U A;  1IX4 A;  1OTV A;  1WNX A;  1T5P A;  1J02 A;  1XK2 A;  2A2M A;  1TO9 B;  1IW1 A;  1RCW A;  4GOH A;  4WWJ A;  3HLX A;  1XJZ A;  1WOV A;  2RGZ A;  2ZVU A;  1XK1 A;  4G7T A;  3IBX A;  3B5O A;  2A2O A;  3HNH A;  1WNW A; 
#chains in the Genus database with same CATH homology
 3DDE A;  1V8X A;  2GM7 A;  1IW0 A;  4G7U A;  2E7E A;  2A6B A;  4RAJ A;  1WZF A;  2QCX A;  1IRM A;  4G7P A;  1Z72 A;  3I9U A;  4G99 A;  4GPC A;  4G8U A;  1TWR A;  1WOW A;  1WZD A;  1XK0 A;  1N3U A;  4MEC A;  3NO6 A;  1WWM A;  1OZE A;  1YAK A;  1IVJ A;  1OTW A;  4FN6 A;  4GPF A;  3CZY A;  4NY7 A;  4G8P A;  1UDD A;  2RD3 A;  1J77 A;  4G8W A;  1WNV A;  1S13 A;  2GM8 A;  1YAF A;  1UBB A;  3HOK A;  3HML A;  1OZR A;  3OQL A;  3BJD A;  1OZL A;  1J2C A;  3RM5 A;  1WOX A;  1P3V A;  2QZC A;  2QPP A;  2F2G A;  1XK3 A;  1TWN A;  4G7L A;  1P3T A;  3B5P A;  3I9T A;  1DVG A;  4WMH A;  1NI6 A;  1WZG A;  1OYL A;  1SK7 A;  5BTQ A;  3I8R A;  4WWZ A;  3MOO A;  3TGM A;  1WE1 A;  4GPH A;  2Q32 A;  1TO9 A;  1DVE A;  1OYK A;  1VGI A;  2DY5 A;  2Q4X A;  4WX0 A;  1N45 A;  1TYH A;  2Z68 A;  3MVU A;  3K4F A;  1RTW A;  1ULX A;  1S8C A;  4G98 A;  1IX3 A;  4LQX A;  1OZW A;  4WD4 A;  1P3U A;  1IX4 A;  1OTV A;  1WNX A;  1T5P A;  1J02 A;  1XK2 A;  2A2M A;  1TO9 B;  1IW1 A;  1RCW A;  4GOH A;  4WWJ A;  3HLX A;  1XJZ A;  1WOV A;  2RGZ A;  2ZVU A;  1XK1 A;  4G7T A;  3IBX A;  3B5O A;  2A2O A;  3HNH A;  1WNW A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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