1VGIA

Crystal structure of xenon bound rat heme-heme oxygenase-1 complex
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
212
structure length
212
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 90
structure length 212
sequence length 212
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2004-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1vgiA00
1P3TA 1WNWA 4G99A 1DVEA 3I8RA 1P3UA 3I9TA 3MOOA 1TYHA 2RGZA 3CZYA 2A2OA 1YAKA 1N45A 2F2GA 1OZWA 1DVGA 1OZRA 1OTWA 1RCWA 1UBBA 1XK1A 1J77A 4WX0A 4G7LA 1VGIA 1TO9B 1OTVA 4LQXA 4WMHA 1OZLA 1XK0A 2DY5A 1TWNA 1WZGA 1V8XA 1WNXA 3B5OA 4G7TA 2Q32A 1TWRA 1XK2A 1J2CA 4WD4A 1WOVA 3I9UA 4G8UA 1SK7A 1IW1A 2GM7A 1P3VA 2QCXA 1WOXA 4GPCA 2A2MA 1WOWA 3IBXA 2A6BA 1NI6A 1XK3A 1XJZA 3OQLA 4MECA 3HNHA 4RAJA 3K4FA 1OZEA 1Z72A 4G98A 1WE1A 2GM8A 2Z68A 3BJDA 3DDEA 1IW0A 1N3UA 1S8CA 1T5PA 4GOHA 3HOKA 2QPPA 3HMLA 4WWZA 2ZVUA 3RM5A 5BTQA 1OYLA 4G8WA 1IVJA 1ULXA 1TO9A 1S13A 1RTWA 4WWJA 2QZCA 3TGMA 2RD3A 4FN6A 4G7UA 4GPHA 4NY7A 1J02A 3MVUA 1IX3A 1WWMA 1IX4A 3NO6A 1UDDA 1WNVA 2Q4XA 3B5PA 4G7PA 4GPFA 4G8PA 2E7EA 1YAFA 3HLXA 1OYKA 1IRMA 1WZFA 1WZDA
chains in the Genus database with same CATH superfamily
1P3TA 1WNWA 4G99A 1DVEA 3I8RA 1P3UA 3I9TA 3MOOA 1TYHA 2RGZA 3CZYA 2A2OA 1YAKA 1N45A 2F2GA 1OZWA 1DVGA 1OZRA 1OTWA 1RCWA 1UBBA 1XK1A 1J77A 4WX0A 4G7LA 1VGIA 1TO9B 1OTVA 4LQXA 4WMHA 1OZLA 1XK0A 2DY5A 1TWNA 1WZGA 1V8XA 1WNXA 3B5OA 4G7TA 2Q32A 1TWRA 1XK2A 1J2CA 4WD4A 1WOVA 3I9UA 4G8UA 1SK7A 1IW1A 2GM7A 1P3VA 2QCXA 1WOXA 2LCUA 4GPCA 2A2MA 1WOWA 3IBXA 2A6BA 1NI6A 1XK3A 1XJZA 3OQLA 4MECA 3HNHA 4RAJA 3K4FA 1OZEA 1Z72A 4G98A 1WE1A 2GM8A 2Z68A 3BJDA 3DDEA 1IW0A 1N3UA 1S8CA 1T5PA 4GOHA 3HOKA 2QPPA 3HMLA 4WWZA 2ZVUA 3RM5A 5BTQA 1OYLA 4G8WA 1IVJA 1ULXA 1TO9A 1S13A 1RTWA 4WWJA 2QZCA 3TGMA 2RD3A 4FN6A 4G7UA 4GPHA 4NY7A 1J02A 3MVUA 1IX3A 1WWMA 1IX4A 3NO6A 1UDDA 1WNVA 2Q4XA 3B5PA 4G7PA 4GPFA 4G8PA 2E7EA 1YAFA 3HLXA 1OYKA 1IRMA 1WZFA 1WZDA
chains in the Genus database with same CATH topology
1P3TA 1WNWA 4G99A 1DVEA 3I8RA 1P3UA 3I9TA 3MOOA 1TYHA 2RGZA 3CZYA 2A2OA 1YAKA 1N45A 2F2GA 1OZWA 1DVGA 1OZRA 1OTWA 1RCWA 1UBBA 1XK1A 1J77A 4WX0A 4G7LA 1VGIA 1TO9B 1OTVA 4LQXA 4WMHA 1OZLA 1XK0A 2DY5A 1TWNA 1WZGA 1V8XA 1WNXA 3B5OA 4G7TA 2Q32A 1TWRA 1XK2A 1J2CA 4WD4A 1WOVA 3I9UA 4G8UA 1SK7A 1IW1A 2GM7A 1P3VA 2QCXA 1WOXA 4GPCA 2A2MA 1WOWA 3IBXA 2A6BA 1NI6A 1XK3A 1XJZA 3OQLA 4MECA 3HNHA 4RAJA 3K4FA 1OZEA 1Z72A 4G98A 1WE1A 2GM8A 2Z68A 3BJDA 3DDEA 1IW0A 1N3UA 1S8CA 1T5PA 4GOHA 3HOKA 2QPPA 3HMLA 4WWZA 2ZVUA 3RM5A 5BTQA 1OYLA 4G8WA 1IVJA 1ULXA 1TO9A 1S13A 1RTWA 4WWJA 2QZCA 3TGMA 2RD3A 4FN6A 4G7UA 4GPHA 4NY7A 1J02A 3MVUA 1IX3A 1WWMA 1IX4A 3NO6A 1UDDA 1WNVA 2Q4XA 3B5PA 4G7PA 4GPFA 4G8PA 2E7EA 1YAFA 3HLXA 1OYKA 1IRMA 1WZFA 1WZDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1P3T A;  1WNW A;  4G99 A;  1DVE A;  3I8R A;  1P3U A;  3I9T A;  3MOO A;  1TYH A;  2RGZ A;  3CZY A;  2A2O A;  1YAK A;  1N45 A;  2F2G A;  1OZW A;  1DVG A;  1OZR A;  1OTW A;  1RCW A;  1UBB A;  1XK1 A;  1J77 A;  4WX0 A;  4G7L A;  1VGI A;  1TO9 B;  1OTV A;  4LQX A;  4WMH A;  1OZL A;  1XK0 A;  2DY5 A;  1TWN A;  1WZG A;  1V8X A;  1WNX A;  3B5O A;  4G7T A;  2Q32 A;  1TWR A;  1XK2 A;  1J2C A;  4WD4 A;  1WOV A;  3I9U A;  4G8U A;  1SK7 A;  1IW1 A;  2GM7 A;  1P3V A;  2QCX A;  1WOX A;  4GPC A;  2A2M A;  1WOW A;  3IBX A;  2A6B A;  1NI6 A;  1XK3 A;  1XJZ A;  3OQL A;  4MEC A;  3HNH A;  4RAJ A;  3K4F A;  1OZE A;  1Z72 A;  4G98 A;  1WE1 A;  2GM8 A;  2Z68 A;  3BJD A;  3DDE A;  1IW0 A;  1N3U A;  1S8C A;  1T5P A;  4GOH A;  3HOK A;  2QPP A;  3HML A;  4WWZ A;  2ZVU A;  3RM5 A;  5BTQ A;  1OYL A;  4G8W A;  1IVJ A;  1ULX A;  1TO9 A;  1S13 A;  1RTW A;  4WWJ A;  2QZC A;  3TGM A;  2RD3 A;  4FN6 A;  4G7U A;  4GPH A;  4NY7 A;  1J02 A;  3MVU A;  1IX3 A;  1WWM A;  1IX4 A;  3NO6 A;  1UDD A;  1WNV A;  2Q4X A;  3B5P A;  4G7P A;  4GPF A;  4G8P A;  2E7E A;  1YAF A;  3HLX A;  1OYK A;  1IRM A;  1WZF A;  1WZD A; 
#chains in the Genus database with same CATH topology
 1P3T A;  1WNW A;  4G99 A;  1DVE A;  3I8R A;  1P3U A;  3I9T A;  3MOO A;  1TYH A;  2RGZ A;  3CZY A;  2A2O A;  1YAK A;  1N45 A;  2F2G A;  1OZW A;  1DVG A;  1OZR A;  1OTW A;  1RCW A;  1UBB A;  1XK1 A;  1J77 A;  4WX0 A;  4G7L A;  1VGI A;  1TO9 B;  1OTV A;  4LQX A;  4WMH A;  1OZL A;  1XK0 A;  2DY5 A;  1TWN A;  1WZG A;  1V8X A;  1WNX A;  3B5O A;  4G7T A;  2Q32 A;  1TWR A;  1XK2 A;  1J2C A;  4WD4 A;  1WOV A;  3I9U A;  4G8U A;  1SK7 A;  1IW1 A;  2GM7 A;  1P3V A;  2QCX A;  1WOX A;  2LCU A;  4GPC A;  2A2M A;  1WOW A;  3IBX A;  2A6B A;  1NI6 A;  1XK3 A;  1XJZ A;  3OQL A;  4MEC A;  3HNH A;  4RAJ A;  3K4F A;  1OZE A;  1Z72 A;  4G98 A;  1WE1 A;  2GM8 A;  2Z68 A;  3BJD A;  3DDE A;  1IW0 A;  1N3U A;  1S8C A;  1T5P A;  4GOH A;  3HOK A;  2QPP A;  3HML A;  4WWZ A;  2ZVU A;  3RM5 A;  5BTQ A;  1OYL A;  4G8W A;  1IVJ A;  1ULX A;  1TO9 A;  1S13 A;  1RTW A;  4WWJ A;  2QZC A;  3TGM A;  2RD3 A;  4FN6 A;  4G7U A;  4GPH A;  4NY7 A;  1J02 A;  3MVU A;  1IX3 A;  1WWM A;  1IX4 A;  3NO6 A;  1UDD A;  1WNV A;  2Q4X A;  3B5P A;  4G7P A;  4GPF A;  4G8P A;  2E7E A;  1YAF A;  3HLX A;  1OYK A;  1IRM A;  1WZF A;  1WZD A; 
#chains in the Genus database with same CATH homology
 1P3T A;  1WNW A;  4G99 A;  1DVE A;  3I8R A;  1P3U A;  3I9T A;  3MOO A;  1TYH A;  2RGZ A;  3CZY A;  2A2O A;  1YAK A;  1N45 A;  2F2G A;  1OZW A;  1DVG A;  1OZR A;  1OTW A;  1RCW A;  1UBB A;  1XK1 A;  1J77 A;  4WX0 A;  4G7L A;  1VGI A;  1TO9 B;  1OTV A;  4LQX A;  4WMH A;  1OZL A;  1XK0 A;  2DY5 A;  1TWN A;  1WZG A;  1V8X A;  1WNX A;  3B5O A;  4G7T A;  2Q32 A;  1TWR A;  1XK2 A;  1J2C A;  4WD4 A;  1WOV A;  3I9U A;  4G8U A;  1SK7 A;  1IW1 A;  2GM7 A;  1P3V A;  2QCX A;  1WOX A;  4GPC A;  2A2M A;  1WOW A;  3IBX A;  2A6B A;  1NI6 A;  1XK3 A;  1XJZ A;  3OQL A;  4MEC A;  3HNH A;  4RAJ A;  3K4F A;  1OZE A;  1Z72 A;  4G98 A;  1WE1 A;  2GM8 A;  2Z68 A;  3BJD A;  3DDE A;  1IW0 A;  1N3U A;  1S8C A;  1T5P A;  4GOH A;  3HOK A;  2QPP A;  3HML A;  4WWZ A;  2ZVU A;  3RM5 A;  5BTQ A;  1OYL A;  4G8W A;  1IVJ A;  1ULX A;  1TO9 A;  1S13 A;  1RTW A;  4WWJ A;  2QZC A;  3TGM A;  2RD3 A;  4FN6 A;  4G7U A;  4GPH A;  4NY7 A;  1J02 A;  3MVU A;  1IX3 A;  1WWM A;  1IX4 A;  3NO6 A;  1UDD A;  1WNV A;  2Q4X A;  3B5P A;  4G7P A;  4GPF A;  4G8P A;  2E7E A;  1YAF A;  3HLX A;  1OYK A;  1IRM A;  1WZF A;  1WZD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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#similar chains, but unknotted
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