1VGIA

Crystal structure of xenon bound rat heme-heme oxygenase-1 complex
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
212
structure length
212
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
pubmed doi rcsb
molecule keywords Heme oxygenase 1
molecule tags Oxidoreductase
source organism Rattus norvegicus
total genus 90
structure length 212
sequence length 212
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2004-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1vgiA00
1TO9A 1SK7A 1OTVA 1XK2A 1WZGA 2A2OA 3CZYA 1OZEA 1OZLA 1P3UA 3OQLA 1IRMA 3HMLA 1UDDA 3HOKA 1T5PA 4G8WA 4G7PA 4G8UA 2QZCA 4GPHA 4MECA 2RGZA 4G98A 1WNXA 1UBBA 1DVEA 1YAKA 1IVJA 1ULXA 4GOHA 3DDEA 4G7LA 2E7EA 2Q32A 4G7TA 4NY7A 1IX4A 1IX3A 2A6BA 3IBXA 2Z68A 4G8PA 4WWJA 4WMHA 1N45A 2GM8A 3HLXA 3NO6A 3K4FA 4G99A 2QCXA 1WZDA 2RD3A 3B5PA 4LQXA 1S13A 1WNVA 4WX0A 2F2GA 3BJDA 3I9UA 1WOXA 3MOOA 1XK1A 3RM5A 4GPFA 1YAFA 2Q4XA 4G7UA 4RAJA 1VGIA 1P3TA 3MVUA 3I8RA 2DY5A 1OZWA 1WOVA 1OYLA 1XK0A 1IW0A 1Z72A 1WWMA 1OYKA 3TGMA 2A2MA 2ZVUA 1NI6A 4FN6A 1RTWA 1DVGA 3I9TA 1XK3A 2QPPA 3HNHA 1N3UA 1WZFA 4GPCA 1TYHA 1XJZA 1TO9B 2GM7A 1S8CA 1P3VA 3B5OA 4WWZA 1J02A 1OZRA 1WOWA 5BTQA 1TWRA 1TWNA 1J77A 1OTWA 1RCWA 1WNWA 1V8XA 1J2CA 4WD4A 1IW1A 1WE1A
chains in the Genus database with same CATH superfamily
1TO9A 1SK7A 1OTVA 1XK2A 1WZGA 2A2OA 3CZYA 1OZEA 1OZLA 1P3UA 3OQLA 1IRMA 3HMLA 1UDDA 3HOKA 1T5PA 4G8WA 2LCUA 4G7PA 2QZCA 4G8UA 4GPHA 4MECA 2RGZA 4G98A 1WNXA 1UBBA 1DVEA 1YAKA 1IVJA 1ULXA 4GOHA 3DDEA 4G7LA 2E7EA 2Q32A 4G7TA 4NY7A 1IX4A 1IX3A 2A6BA 3IBXA 2Z68A 4G8PA 4WWJA 4WMHA 1N45A 2GM8A 3HLXA 3NO6A 3K4FA 4G99A 2QCXA 1WZDA 2RD3A 3B5PA 4LQXA 1S13A 1WNVA 4WX0A 2F2GA 3BJDA 3I9UA 1WOXA 3MOOA 1XK1A 3RM5A 4GPFA 1YAFA 2Q4XA 4G7UA 4RAJA 1VGIA 1P3TA 3MVUA 3I8RA 2DY5A 1OZWA 1WOVA 1OYLA 1XK0A 1IW0A 1Z72A 1WWMA 1OYKA 3TGMA 2A2MA 2ZVUA 1NI6A 4FN6A 1RTWA 1DVGA 3I9TA 1XK3A 2QPPA 3HNHA 1N3UA 1WZFA 4GPCA 1TYHA 1XJZA 1TO9B 2GM7A 1S8CA 1P3VA 3B5OA 4WWZA 1J02A 1OZRA 1WOWA 5BTQA 1TWRA 1TWNA 1J77A 1OTWA 1RCWA 1WNWA 1V8XA 1J2CA 4WD4A 1IW1A 1WE1A
chains in the Genus database with same CATH topology
1TO9A 1SK7A 1OTVA 1XK2A 1WZGA 2A2OA 3CZYA 1OZEA 1OZLA 1P3UA 3OQLA 1IRMA 3HMLA 1UDDA 3HOKA 1T5PA 4G8WA 4G7PA 4G8UA 2QZCA 4GPHA 4MECA 2RGZA 4G98A 1WNXA 1UBBA 1DVEA 1YAKA 1IVJA 1ULXA 4GOHA 3DDEA 4G7LA 2E7EA 2Q32A 4G7TA 4NY7A 1IX4A 1IX3A 2A6BA 3IBXA 2Z68A 4G8PA 4WWJA 4WMHA 1N45A 2GM8A 3HLXA 3NO6A 3K4FA 4G99A 2QCXA 1WZDA 2RD3A 3B5PA 4LQXA 1S13A 1WNVA 4WX0A 2F2GA 3BJDA 3I9UA 1WOXA 3MOOA 1XK1A 3RM5A 4GPFA 1YAFA 2Q4XA 4G7UA 4RAJA 1VGIA 1P3TA 3MVUA 3I8RA 2DY5A 1OZWA 1WOVA 1OYLA 1XK0A 1IW0A 1Z72A 1WWMA 1OYKA 3TGMA 2A2MA 2ZVUA 1NI6A 4FN6A 1RTWA 1DVGA 3I9TA 1XK3A 2QPPA 3HNHA 1N3UA 1WZFA 4GPCA 1TYHA 1XJZA 1TO9B 2GM7A 1S8CA 1P3VA 3B5OA 4WWZA 1J02A 1OZRA 1WOWA 5BTQA 1TWRA 1TWNA 1J77A 1OTWA 1RCWA 1WNWA 1V8XA 1J2CA 4WD4A 1IW1A 1WE1A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1TO9 A;  1SK7 A;  1OTV A;  1XK2 A;  1WZG A;  2A2O A;  3CZY A;  1OZE A;  1OZL A;  1P3U A;  3OQL A;  1IRM A;  3HML A;  1UDD A;  3HOK A;  1T5P A;  4G8W A;  4G7P A;  4G8U A;  2QZC A;  4GPH A;  4MEC A;  2RGZ A;  4G98 A;  1WNX A;  1UBB A;  1DVE A;  1YAK A;  1IVJ A;  1ULX A;  4GOH A;  3DDE A;  4G7L A;  2E7E A;  2Q32 A;  4G7T A;  4NY7 A;  1IX4 A;  1IX3 A;  2A6B A;  3IBX A;  2Z68 A;  4G8P A;  4WWJ A;  4WMH A;  1N45 A;  2GM8 A;  3HLX A;  3NO6 A;  3K4F A;  4G99 A;  2QCX A;  1WZD A;  2RD3 A;  3B5P A;  4LQX A;  1S13 A;  1WNV A;  4WX0 A;  2F2G A;  3BJD A;  3I9U A;  1WOX A;  3MOO A;  1XK1 A;  3RM5 A;  4GPF A;  1YAF A;  2Q4X A;  4G7U A;  4RAJ A;  1VGI A;  1P3T A;  3MVU A;  3I8R A;  2DY5 A;  1OZW A;  1WOV A;  1OYL A;  1XK0 A;  1IW0 A;  1Z72 A;  1WWM A;  1OYK A;  3TGM A;  2A2M A;  2ZVU A;  1NI6 A;  4FN6 A;  1RTW A;  1DVG A;  3I9T A;  1XK3 A;  2QPP A;  3HNH A;  1N3U A;  1WZF A;  4GPC A;  1TYH A;  1XJZ A;  1TO9 B;  2GM7 A;  1S8C A;  1P3V A;  3B5O A;  4WWZ A;  1J02 A;  1OZR A;  1WOW A;  5BTQ A;  1TWR A;  1TWN A;  1J77 A;  1OTW A;  1RCW A;  1WNW A;  1V8X A;  1J2C A;  4WD4 A;  1IW1 A;  1WE1 A; 
#chains in the Genus database with same CATH topology
 1TO9 A;  1SK7 A;  1OTV A;  1XK2 A;  1WZG A;  2A2O A;  3CZY A;  1OZE A;  1OZL A;  1P3U A;  3OQL A;  1IRM A;  3HML A;  1UDD A;  3HOK A;  1T5P A;  4G8W A;  2LCU A;  4G7P A;  2QZC A;  4G8U A;  4GPH A;  4MEC A;  2RGZ A;  4G98 A;  1WNX A;  1UBB A;  1DVE A;  1YAK A;  1IVJ A;  1ULX A;  4GOH A;  3DDE A;  4G7L A;  2E7E A;  2Q32 A;  4G7T A;  4NY7 A;  1IX4 A;  1IX3 A;  2A6B A;  3IBX A;  2Z68 A;  4G8P A;  4WWJ A;  4WMH A;  1N45 A;  2GM8 A;  3HLX A;  3NO6 A;  3K4F A;  4G99 A;  2QCX A;  1WZD A;  2RD3 A;  3B5P A;  4LQX A;  1S13 A;  1WNV A;  4WX0 A;  2F2G A;  3BJD A;  3I9U A;  1WOX A;  3MOO A;  1XK1 A;  3RM5 A;  4GPF A;  1YAF A;  2Q4X A;  4G7U A;  4RAJ A;  1VGI A;  1P3T A;  3MVU A;  3I8R A;  2DY5 A;  1OZW A;  1WOV A;  1OYL A;  1XK0 A;  1IW0 A;  1Z72 A;  1WWM A;  1OYK A;  3TGM A;  2A2M A;  2ZVU A;  1NI6 A;  4FN6 A;  1RTW A;  1DVG A;  3I9T A;  1XK3 A;  2QPP A;  3HNH A;  1N3U A;  1WZF A;  4GPC A;  1TYH A;  1XJZ A;  1TO9 B;  2GM7 A;  1S8C A;  1P3V A;  3B5O A;  4WWZ A;  1J02 A;  1OZR A;  1WOW A;  5BTQ A;  1TWR A;  1TWN A;  1J77 A;  1OTW A;  1RCW A;  1WNW A;  1V8X A;  1J2C A;  4WD4 A;  1IW1 A;  1WE1 A; 
#chains in the Genus database with same CATH homology
 1TO9 A;  1SK7 A;  1OTV A;  1XK2 A;  1WZG A;  2A2O A;  3CZY A;  1OZE A;  1OZL A;  1P3U A;  3OQL A;  1IRM A;  3HML A;  1UDD A;  3HOK A;  1T5P A;  4G8W A;  4G7P A;  4G8U A;  2QZC A;  4GPH A;  4MEC A;  2RGZ A;  4G98 A;  1WNX A;  1UBB A;  1DVE A;  1YAK A;  1IVJ A;  1ULX A;  4GOH A;  3DDE A;  4G7L A;  2E7E A;  2Q32 A;  4G7T A;  4NY7 A;  1IX4 A;  1IX3 A;  2A6B A;  3IBX A;  2Z68 A;  4G8P A;  4WWJ A;  4WMH A;  1N45 A;  2GM8 A;  3HLX A;  3NO6 A;  3K4F A;  4G99 A;  2QCX A;  1WZD A;  2RD3 A;  3B5P A;  4LQX A;  1S13 A;  1WNV A;  4WX0 A;  2F2G A;  3BJD A;  3I9U A;  1WOX A;  3MOO A;  1XK1 A;  3RM5 A;  4GPF A;  1YAF A;  2Q4X A;  4G7U A;  4RAJ A;  1VGI A;  1P3T A;  3MVU A;  3I8R A;  2DY5 A;  1OZW A;  1WOV A;  1OYL A;  1XK0 A;  1IW0 A;  1Z72 A;  1WWM A;  1OYK A;  3TGM A;  2A2M A;  2ZVU A;  1NI6 A;  4FN6 A;  1RTW A;  1DVG A;  3I9T A;  1XK3 A;  2QPP A;  3HNH A;  1N3U A;  1WZF A;  4GPC A;  1TYH A;  1XJZ A;  1TO9 B;  2GM7 A;  1S8C A;  1P3V A;  3B5O A;  4WWZ A;  1J02 A;  1OZR A;  1WOW A;  5BTQ A;  1TWR A;  1TWN A;  1J77 A;  1OTW A;  1RCW A;  1WNW A;  1V8X A;  1J2C A;  4WD4 A;  1IW1 A;  1WE1 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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#similar chains, but unknotted
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