1XK0A

Crystal structures of the g139a, g139a-no and g143h mutants of human heme oxygenase-1
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
214
structure length
214
Chain Sequence
PQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLADLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYESRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Heme oxygenase 1
total genus 83
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2004-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1xk0A00
2GM7A 1OTVA 3MVUA 1XK2A 1WNWA 3MOOA 1IW0A 2A6BA 4G99A 3K4FA 1SK7A 3I8RA 2QZCA 1IRMA 1TWRA 4WX0A 4LQXA 4NY7A 2DY5A 4G7PA 1IW1A 1RCWA 1OTWA 3NO6A 4G7UA 1XK1A 1VGIA 2GM8A 3OQLA 1IVJA 1N45A 2A2OA 1YAKA 1P3UA 1OYKA 1T5PA 1P3VA 1IX4A 1WWMA 2RD3A 3CZYA 2Q4XA 4WWZA 1J02A 4GOHA 4WWJA 2Q32A 1OZEA 1S8CA 4GPFA 1DVGA 1WOVA 3HMLA 2QCXA 1S13A 1WZDA 2Z68A 3IBXA 3HNHA 1OZWA 4FN6A 1XK3A 4GPHA 1OYLA 1WZGA 1NI6A 2RGZA 3B5OA 1WZFA 2E7EA 1DVEA 3BJDA 1TO9A 2A2MA 4G8UA 4GPCA 1J77A 3TGMA 1WNVA 2QPPA 3RM5A 3HLXA 1OZLA 1XJZA 2F2GA 1J2CA 1UBBA 1P3TA 1IX3A 1YAFA 4WMHA 3I9TA 1RTWA 1WNXA 3DDEA 3I9UA 1UDDA 4MECA 3HOKA 1TO9B 1WOXA 1TWNA 4G8PA 1N3UA 4G7LA 1V8XA 1OZRA 1XK0A 2ZVUA 1Z72A 4G7TA 4RAJA 1WE1A 1ULXA 3B5PA 4G8WA 1WOWA 4G98A 5BTQA 4WD4A 1TYHA
chains in the Genus database with same CATH superfamily
2GM7A 1OTVA 3MVUA 1XK2A 1WNWA 3MOOA 1IW0A 2A6BA 4G99A 3K4FA 1SK7A 3I8RA 2QZCA 1IRMA 1TWRA 4WX0A 4LQXA 4NY7A 2DY5A 4G7PA 1IW1A 1RCWA 1OTWA 3NO6A 4G7UA 1XK1A 1VGIA 2GM8A 3OQLA 1IVJA 1N45A 2A2OA 1YAKA 1P3UA 1OYKA 1T5PA 1P3VA 1IX4A 1WWMA 2RD3A 3CZYA 2Q4XA 4WWZA 1J02A 4GOHA 4WWJA 2Q32A 1OZEA 1S8CA 4GPFA 1DVGA 1WOVA 3HMLA 2QCXA 1S13A 1WZDA 2Z68A 3IBXA 3HNHA 1OZWA 4FN6A 1XK3A 4GPHA 1OYLA 1WZGA 1NI6A 2RGZA 3B5OA 1WZFA 2E7EA 1DVEA 3BJDA 2LCUA 1TO9A 2A2MA 4G8UA 4GPCA 1J77A 3TGMA 1WNVA 2QPPA 3RM5A 3HLXA 1OZLA 1XJZA 2F2GA 1J2CA 1UBBA 1P3TA 1IX3A 1YAFA 4WMHA 3I9TA 1RTWA 1WNXA 3DDEA 3I9UA 1UDDA 4MECA 3HOKA 1TO9B 1WOXA 1TWNA 4G8PA 1N3UA 4G7LA 1V8XA 1OZRA 1XK0A 2ZVUA 1Z72A 4G7TA 4RAJA 1WE1A 1ULXA 3B5PA 4G8WA 1WOWA 4G98A 5BTQA 4WD4A 1TYHA
chains in the Genus database with same CATH topology
2GM7A 1OTVA 3MVUA 1XK2A 1WNWA 3MOOA 1IW0A 2A6BA 4G99A 3K4FA 1SK7A 3I8RA 2QZCA 1IRMA 1TWRA 4WX0A 4LQXA 4NY7A 2DY5A 4G7PA 1IW1A 1RCWA 1OTWA 3NO6A 4G7UA 1XK1A 1VGIA 2GM8A 3OQLA 1IVJA 1N45A 2A2OA 1YAKA 1P3UA 1OYKA 1T5PA 1P3VA 1IX4A 1WWMA 2RD3A 3CZYA 2Q4XA 4WWZA 1J02A 4GOHA 4WWJA 2Q32A 1OZEA 1S8CA 4GPFA 1DVGA 1WOVA 3HMLA 2QCXA 1S13A 1WZDA 2Z68A 3IBXA 3HNHA 1OZWA 4FN6A 1XK3A 4GPHA 1OYLA 1WZGA 1NI6A 2RGZA 3B5OA 1WZFA 2E7EA 1DVEA 3BJDA 1TO9A 2A2MA 4G8UA 4GPCA 1J77A 3TGMA 1WNVA 2QPPA 3RM5A 3HLXA 1OZLA 1XJZA 2F2GA 1J2CA 1UBBA 1P3TA 1IX3A 1YAFA 4WMHA 3I9TA 1RTWA 1WNXA 3DDEA 3I9UA 1UDDA 4MECA 3HOKA 1TO9B 1WOXA 1TWNA 4G8PA 1N3UA 4G7LA 1V8XA 1OZRA 1XK0A 2ZVUA 1Z72A 4G7TA 4RAJA 1WE1A 1ULXA 3B5PA 4G8WA 1WOWA 4G98A 5BTQA 4WD4A 1TYHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GM7 A;  1OTV A;  3MVU A;  1XK2 A;  1WNW A;  3MOO A;  1IW0 A;  2A6B A;  4G99 A;  3K4F A;  1SK7 A;  3I8R A;  2QZC A;  1IRM A;  1TWR A;  4WX0 A;  4LQX A;  4NY7 A;  2DY5 A;  4G7P A;  1IW1 A;  1RCW A;  1OTW A;  3NO6 A;  4G7U A;  1XK1 A;  1VGI A;  2GM8 A;  3OQL A;  1IVJ A;  1N45 A;  2A2O A;  1YAK A;  1P3U A;  1OYK A;  1T5P A;  1P3V A;  1IX4 A;  1WWM A;  2RD3 A;  3CZY A;  2Q4X A;  4WWZ A;  1J02 A;  4GOH A;  4WWJ A;  2Q32 A;  1OZE A;  1S8C A;  4GPF A;  1DVG A;  1WOV A;  3HML A;  2QCX A;  1S13 A;  1WZD A;  2Z68 A;  3IBX A;  3HNH A;  1OZW A;  4FN6 A;  1XK3 A;  4GPH A;  1OYL A;  1WZG A;  1NI6 A;  2RGZ A;  3B5O A;  1WZF A;  2E7E A;  1DVE A;  3BJD A;  1TO9 A;  2A2M A;  4G8U A;  4GPC A;  1J77 A;  3TGM A;  1WNV A;  2QPP A;  3RM5 A;  3HLX A;  1OZL A;  1XJZ A;  2F2G A;  1J2C A;  1UBB A;  1P3T A;  1IX3 A;  1YAF A;  4WMH A;  3I9T A;  1RTW A;  1WNX A;  3DDE A;  3I9U A;  1UDD A;  4MEC A;  3HOK A;  1TO9 B;  1WOX A;  1TWN A;  4G8P A;  1N3U A;  4G7L A;  1V8X A;  1OZR A;  1XK0 A;  2ZVU A;  1Z72 A;  4G7T A;  4RAJ A;  1WE1 A;  1ULX A;  3B5P A;  4G8W A;  1WOW A;  4G98 A;  5BTQ A;  4WD4 A;  1TYH A; 
#chains in the Genus database with same CATH topology
 2GM7 A;  1OTV A;  3MVU A;  1XK2 A;  1WNW A;  3MOO A;  1IW0 A;  2A6B A;  4G99 A;  3K4F A;  1SK7 A;  3I8R A;  2QZC A;  1IRM A;  1TWR A;  4WX0 A;  4LQX A;  4NY7 A;  2DY5 A;  4G7P A;  1IW1 A;  1RCW A;  1OTW A;  3NO6 A;  4G7U A;  1XK1 A;  1VGI A;  2GM8 A;  3OQL A;  1IVJ A;  1N45 A;  2A2O A;  1YAK A;  1P3U A;  1OYK A;  1T5P A;  1P3V A;  1IX4 A;  1WWM A;  2RD3 A;  3CZY A;  2Q4X A;  4WWZ A;  1J02 A;  4GOH A;  4WWJ A;  2Q32 A;  1OZE A;  1S8C A;  4GPF A;  1DVG A;  1WOV A;  3HML A;  2QCX A;  1S13 A;  1WZD A;  2Z68 A;  3IBX A;  3HNH A;  1OZW A;  4FN6 A;  1XK3 A;  4GPH A;  1OYL A;  1WZG A;  1NI6 A;  2RGZ A;  3B5O A;  1WZF A;  2E7E A;  1DVE A;  3BJD A;  2LCU A;  1TO9 A;  2A2M A;  4G8U A;  4GPC A;  1J77 A;  3TGM A;  1WNV A;  2QPP A;  3RM5 A;  3HLX A;  1OZL A;  1XJZ A;  2F2G A;  1J2C A;  1UBB A;  1P3T A;  1IX3 A;  1YAF A;  4WMH A;  3I9T A;  1RTW A;  1WNX A;  3DDE A;  3I9U A;  1UDD A;  4MEC A;  3HOK A;  1TO9 B;  1WOX A;  1TWN A;  4G8P A;  1N3U A;  4G7L A;  1V8X A;  1OZR A;  1XK0 A;  2ZVU A;  1Z72 A;  4G7T A;  4RAJ A;  1WE1 A;  1ULX A;  3B5P A;  4G8W A;  1WOW A;  4G98 A;  5BTQ A;  4WD4 A;  1TYH A; 
#chains in the Genus database with same CATH homology
 2GM7 A;  1OTV A;  3MVU A;  1XK2 A;  1WNW A;  3MOO A;  1IW0 A;  2A6B A;  4G99 A;  3K4F A;  1SK7 A;  3I8R A;  2QZC A;  1IRM A;  1TWR A;  4WX0 A;  4LQX A;  4NY7 A;  2DY5 A;  4G7P A;  1IW1 A;  1RCW A;  1OTW A;  3NO6 A;  4G7U A;  1XK1 A;  1VGI A;  2GM8 A;  3OQL A;  1IVJ A;  1N45 A;  2A2O A;  1YAK A;  1P3U A;  1OYK A;  1T5P A;  1P3V A;  1IX4 A;  1WWM A;  2RD3 A;  3CZY A;  2Q4X A;  4WWZ A;  1J02 A;  4GOH A;  4WWJ A;  2Q32 A;  1OZE A;  1S8C A;  4GPF A;  1DVG A;  1WOV A;  3HML A;  2QCX A;  1S13 A;  1WZD A;  2Z68 A;  3IBX A;  3HNH A;  1OZW A;  4FN6 A;  1XK3 A;  4GPH A;  1OYL A;  1WZG A;  1NI6 A;  2RGZ A;  3B5O A;  1WZF A;  2E7E A;  1DVE A;  3BJD A;  1TO9 A;  2A2M A;  4G8U A;  4GPC A;  1J77 A;  3TGM A;  1WNV A;  2QPP A;  3RM5 A;  3HLX A;  1OZL A;  1XJZ A;  2F2G A;  1J2C A;  1UBB A;  1P3T A;  1IX3 A;  1YAF A;  4WMH A;  3I9T A;  1RTW A;  1WNX A;  3DDE A;  3I9U A;  1UDD A;  4MEC A;  3HOK A;  1TO9 B;  1WOX A;  1TWN A;  4G8P A;  1N3U A;  4G7L A;  1V8X A;  1OZR A;  1XK0 A;  2ZVU A;  1Z72 A;  4G7T A;  4RAJ A;  1WE1 A;  1ULX A;  3B5P A;  4G8W A;  1WOW A;  4G98 A;  5BTQ A;  4WD4 A;  1TYH A; 
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