2BT2A

Structure of the regulator of g-protein signaling 16
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
143
structure length
143
Chain Sequence
NLYFQSMRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits.
pubmed doi rcsb
molecule keywords REGULATOR OF G-PROTEIN SIGNALING 16
molecule tags Signaling protein
source organism Homo sapiens
total genus 57
structure length 143
sequence length 143
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2bt2A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2bt2A01
3KRWA 3PVUA 2AF0A 3UZTA 3NYNA 2CRPA 2OWIA 5HE2A 1FQJB 1DK8A 2IHDA 3C7KB 1CMZA 2DLVA 2BCJA 2BT2A 2ODEB 2V4ZB 3KRXA 1EZTA 2BV1A 2IHBB 2IK8B 1FQKB 2OJ4A 3V5WA 1EZYA 3CIKA 5HE0A 4TNDA 3PSCA 5HE3A 2JNUA 2GTPC 3NYOA 4TNBA 5HE1A 4EKDB 1OMWA 4PNKA 5DO9B 3PVWA 4MK0A 1AGRE 2JM5A 3C7LA 2EBZA 1EMUA 1FQIA 2D9JA
chains in the Genus database with same CATH superfamily
3KRWA 3PVUA 2AF0A 3UZTA 3NYNA 2CRPA 5REQB 2OWIA 5HE2A 1FQJB 1DK8A 2IHDA 3C7KB 1CMZA 2DLVA 2BCJA 2BT2A 2ODEB 2V4ZB 3KRXA 1EZTA 2BV1A 2IHBB 2IK8B 1FQKB 2OJ4A 3V5WA 1EZYA 3CIKA 5HE0A 4TNDA 3PSCA 5HE3A 2JNUA 2GTPC 3NYOA 4TNBA 5HE1A 4EKDB 1OMWA 4PNKA 5DO9B 3QYFA 3PVWA 4HTEA 4MK0A 1AGRE 3I5QA 2JM5A 3C7LA 2EBZA 1EMUA 1FQIA 2D9JA
chains in the Genus database with same CATH topology
3KRWA 3PVUA 2AF0A 3UZTA 3NYNA 2CRPA 5REQB 2OWIA 5HE2A 1FQJB 1DK8A 2IHDA 3C7KB 1CMZA 2DLVA 2BCJA 2BT2A 2ODEB 2V4ZB 3KRXA 1EZTA 2BV1A 2IHBB 2IK8B 1FQKB 2OJ4A 3V5WA 1EZYA 3CIKA 5HE0A 4TNDA 3PSCA 5HE3A 2JNUA 2GTPC 3NYOA 4TNBA 5HE1A 4EKDB 1OMWA 4PNKA 5DO9B 3QYFA 3PVWA 4MK0A 1AGRE 2JM5A 3C7LA 2EBZA 1EMUA 1FQIA 2D9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRW A;  3PVU A;  2AF0 A;  3UZT A;  3NYN A;  2CRP A;  2OWI A;  5HE2 A;  1FQJ B;  1DK8 A;  2IHD A;  3C7K B;  1CMZ A;  2DLV A;  2BCJ A;  2BT2 A;  2ODE B;  2V4Z B;  3KRX A;  1EZT A;  2BV1 A;  2IHB B;  2IK8 B;  1FQK B;  2OJ4 A;  3V5W A;  1EZY A;  3CIK A;  5HE0 A;  4TND A;  3PSC A;  5HE3 A;  2JNU A;  2GTP C;  3NYO A;  4TNB A;  5HE1 A;  4EKD B;  1OMW A;  4PNK A;  5DO9 B;  3PVW A;  4MK0 A;  1AGR E;  2JM5 A;  3C7L A;  2EBZ A;  1EMU A;  1FQI A;  2D9J A; 
#chains in the Genus database with same CATH topology
 3KRW A;  3PVU A;  2AF0 A;  3UZT A;  3NYN A;  2CRP A;  5REQ B;  2OWI A;  5HE2 A;  1FQJ B;  1DK8 A;  2IHD A;  3C7K B;  1CMZ A;  2DLV A;  2BCJ A;  2BT2 A;  2ODE B;  2V4Z B;  3KRX A;  1EZT A;  2BV1 A;  2IHB B;  2IK8 B;  1FQK B;  2OJ4 A;  3V5W A;  1EZY A;  3CIK A;  5HE0 A;  4TND A;  3PSC A;  5HE3 A;  2JNU A;  2GTP C;  3NYO A;  4TNB A;  5HE1 A;  4EKD B;  1OMW A;  4PNK A;  5DO9 B;  3QYF A;  3PVW A;  4HTE A;  4MK0 A;  1AGR E;  3I5Q A;  2JM5 A;  3C7L A;  2EBZ A;  1EMU A;  1FQI A;  2D9J A; 
#chains in the Genus database with same CATH homology
 3KRW A;  3PVU A;  2AF0 A;  3UZT A;  3NYN A;  2CRP A;  5REQ B;  2OWI A;  5HE2 A;  1FQJ B;  1DK8 A;  2IHD A;  3C7K B;  1CMZ A;  2DLV A;  2BCJ A;  2BT2 A;  2ODE B;  2V4Z B;  3KRX A;  1EZT A;  2BV1 A;  2IHB B;  2IK8 B;  1FQK B;  2OJ4 A;  3V5W A;  1EZY A;  3CIK A;  5HE0 A;  4TND A;  3PSC A;  5HE3 A;  2JNU A;  2GTP C;  3NYO A;  4TNB A;  5HE1 A;  4EKD B;  1OMW A;  4PNK A;  5DO9 B;  3QYF A;  3PVW A;  4MK0 A;  1AGR E;  2JM5 A;  3C7L A;  2EBZ A;  1EMU A;  1FQI A;  2D9J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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