2BT2A

Structure of the regulator of g-protein signaling 16
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
143
structure length
143
Chain Sequence
NLYFQSMRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords REGULATOR OF G-PROTEIN SIGNALING 16
total genus 57
structure length 143
sequence length 143
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2bt2A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2bt2A01
3CIKA 2BT2A 3C7LA 1EZTA 3PVUA 1DK8A 2JM5A 2JNUA 1EZYA 2V4ZB 3PSCA 4MK0A 1FQIA 5HE0A 4EKDB 2DLVA 1FQKB 1FQJB 2EBZA 2BV1A 2BCJA 3NYNA 4TNDA 3UZTA 2D9JA 3KRWA 1OMWA 3NYOA 2GTPC 2IHBB 3KRXA 4TNBA 2OJ4A 2IK8B 5HE3A 2OWIA 2AF0A 1EMUA 5DO9B 3C7KB 1CMZA 5HE2A 3V5WA 2ODEB 4PNKA 2CRPA 2IHDA 1AGRE 3PVWA 5HE1A
chains in the Genus database with same CATH superfamily
3QYFA 3CIKA 2BT2A 3C7LA 1EZTA 3I5QA 3PVUA 1DK8A 2JM5A 2JNUA 1EZYA 2V4ZB 3PSCA 4HTEA 4MK0A 1FQIA 5HE0A 4EKDB 2DLVA 1FQKB 1FQJB 2EBZA 2BV1A 2BCJA 3NYNA 4TNDA 3UZTA 2D9JA 3KRWA 1OMWA 3NYOA 2GTPC 2IHBB 3KRXA 4TNBA 2OJ4A 2IK8B 5HE3A 2OWIA 2AF0A 1EMUA 5DO9B 3C7KB 1CMZA 5REQB 5HE2A 3V5WA 2ODEB 4PNKA 2CRPA 2IHDA 1AGRE 3PVWA 5HE1A
chains in the Genus database with same CATH topology
3QYFA 3CIKA 2BT2A 3C7LA 1EZTA 3PVUA 1DK8A 2JM5A 2JNUA 1EZYA 2V4ZB 3PSCA 4MK0A 1FQIA 5HE0A 4EKDB 2DLVA 1FQKB 1FQJB 2EBZA 2BV1A 2BCJA 3NYNA 4TNDA 3UZTA 2D9JA 3KRWA 1OMWA 3NYOA 2GTPC 2IHBB 3KRXA 4TNBA 2OJ4A 2IK8B 5HE3A 2OWIA 2AF0A 1EMUA 5DO9B 3C7KB 1CMZA 5REQB 5HE2A 3V5WA 2ODEB 4PNKA 2CRPA 2IHDA 1AGRE 3PVWA 5HE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CIK A;  2BT2 A;  3C7L A;  1EZT A;  3PVU A;  1DK8 A;  2JM5 A;  2JNU A;  1EZY A;  2V4Z B;  3PSC A;  4MK0 A;  1FQI A;  5HE0 A;  4EKD B;  2DLV A;  1FQK B;  1FQJ B;  2EBZ A;  2BV1 A;  2BCJ A;  3NYN A;  4TND A;  3UZT A;  2D9J A;  3KRW A;  1OMW A;  3NYO A;  2GTP C;  2IHB B;  3KRX A;  4TNB A;  2OJ4 A;  2IK8 B;  5HE3 A;  2OWI A;  2AF0 A;  1EMU A;  5DO9 B;  3C7K B;  1CMZ A;  5HE2 A;  3V5W A;  2ODE B;  4PNK A;  2CRP A;  2IHD A;  1AGR E;  3PVW A;  5HE1 A; 
#chains in the Genus database with same CATH topology
 3QYF A;  3CIK A;  2BT2 A;  3C7L A;  1EZT A;  3I5Q A;  3PVU A;  1DK8 A;  2JM5 A;  2JNU A;  1EZY A;  2V4Z B;  3PSC A;  4HTE A;  4MK0 A;  1FQI A;  5HE0 A;  4EKD B;  2DLV A;  1FQK B;  1FQJ B;  2EBZ A;  2BV1 A;  2BCJ A;  3NYN A;  4TND A;  3UZT A;  2D9J A;  3KRW A;  1OMW A;  3NYO A;  2GTP C;  2IHB B;  3KRX A;  4TNB A;  2OJ4 A;  2IK8 B;  5HE3 A;  2OWI A;  2AF0 A;  1EMU A;  5DO9 B;  3C7K B;  1CMZ A;  5REQ B;  5HE2 A;  3V5W A;  2ODE B;  4PNK A;  2CRP A;  2IHD A;  1AGR E;  3PVW A;  5HE1 A; 
#chains in the Genus database with same CATH homology
 3QYF A;  3CIK A;  2BT2 A;  3C7L A;  1EZT A;  3PVU A;  1DK8 A;  2JM5 A;  2JNU A;  1EZY A;  2V4Z B;  3PSC A;  4MK0 A;  1FQI A;  5HE0 A;  4EKD B;  2DLV A;  1FQK B;  1FQJ B;  2EBZ A;  2BV1 A;  2BCJ A;  3NYN A;  4TND A;  3UZT A;  2D9J A;  3KRW A;  1OMW A;  3NYO A;  2GTP C;  2IHB B;  3KRX A;  4TNB A;  2OJ4 A;  2IK8 B;  5HE3 A;  2OWI A;  2AF0 A;  1EMU A;  5DO9 B;  3C7K B;  1CMZ A;  5REQ B;  5HE2 A;  3V5W A;  2ODE B;  4PNK A;  2CRP A;  2IHD A;  1AGR E;  3PVW A;  5HE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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