2BV1A

Regulator of g-protein signalling 1 (human)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
134
structure length
134
Chain Sequence
KDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords REGULATOR OF G-PROTEIN SIGNALLING 1
total genus 46
structure length 134
sequence length 134
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2bv1A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2bv1A01
2JNUA 3NYNA 2AF0A 4TNDA 2V4ZB 2BT2A 2IHDA 2CRPA 2IK8B 1DK8A 3CIKA 2OWIA 5DO9B 2BV1A 4PNKA 1EMUA 2D9JA 2ODEB 2GTPC 3V5WA 4EKDB 3KRXA 3PVWA 5HE2A 1CMZA 1EZYA 5HE0A 4MK0A 1FQJB 2DLVA 2EBZA 2JM5A 2OJ4A 3C7LA 3PVUA 3UZTA 5HE3A 2IHBB 4TNBA 5HE1A 1OMWA 1FQIA 3NYOA 3C7KB 1AGRE 2BCJA 1EZTA 3KRWA 3PSCA 1FQKB
chains in the Genus database with same CATH superfamily
2JNUA 3NYNA 2AF0A 4TNDA 2V4ZB 2BT2A 2IHDA 2CRPA 2IK8B 1DK8A 3CIKA 2OWIA 5DO9B 2BV1A 4PNKA 1EMUA 2D9JA 2ODEB 2GTPC 3V5WA 4EKDB 3KRXA 3PVWA 5HE2A 1CMZA 1EZYA 5HE0A 3QYFA 3I5QA 4MK0A 1FQJB 2DLVA 2EBZA 2JM5A 2OJ4A 3C7LA 3PVUA 3UZTA 5HE3A 2IHBB 4TNBA 5HE1A 1OMWA 1FQIA 3NYOA 3C7KB 1AGRE 2BCJA 5REQB 1EZTA 4HTEA 3KRWA 3PSCA 1FQKB
chains in the Genus database with same CATH topology
2JNUA 3NYNA 2AF0A 4TNDA 2V4ZB 2BT2A 2IHDA 2CRPA 2IK8B 1DK8A 3CIKA 2OWIA 5DO9B 2BV1A 4PNKA 1EMUA 2D9JA 2ODEB 2GTPC 3V5WA 4EKDB 3KRXA 3PVWA 5HE2A 1CMZA 1EZYA 5HE0A 3QYFA 4MK0A 1FQJB 2DLVA 2EBZA 2JM5A 2OJ4A 3C7LA 3PVUA 3UZTA 5HE3A 2IHBB 4TNBA 5HE1A 1OMWA 1FQIA 3NYOA 3C7KB 1AGRE 2BCJA 5REQB 1EZTA 3KRWA 3PSCA 1FQKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JNU A;  3NYN A;  2AF0 A;  4TND A;  2V4Z B;  2BT2 A;  2IHD A;  2CRP A;  2IK8 B;  1DK8 A;  3CIK A;  2OWI A;  5DO9 B;  2BV1 A;  4PNK A;  1EMU A;  2D9J A;  2ODE B;  2GTP C;  3V5W A;  4EKD B;  3KRX A;  3PVW A;  5HE2 A;  1CMZ A;  1EZY A;  5HE0 A;  4MK0 A;  1FQJ B;  2DLV A;  2EBZ A;  2JM5 A;  2OJ4 A;  3C7L A;  3PVU A;  3UZT A;  5HE3 A;  2IHB B;  4TNB A;  5HE1 A;  1OMW A;  1FQI A;  3NYO A;  3C7K B;  1AGR E;  2BCJ A;  1EZT A;  3KRW A;  3PSC A;  1FQK B; 
#chains in the Genus database with same CATH topology
 2JNU A;  3NYN A;  2AF0 A;  4TND A;  2V4Z B;  2BT2 A;  2IHD A;  2CRP A;  2IK8 B;  1DK8 A;  3CIK A;  2OWI A;  5DO9 B;  2BV1 A;  4PNK A;  1EMU A;  2D9J A;  2ODE B;  2GTP C;  3V5W A;  4EKD B;  3KRX A;  3PVW A;  5HE2 A;  1CMZ A;  1EZY A;  5HE0 A;  3QYF A;  3I5Q A;  4MK0 A;  1FQJ B;  2DLV A;  2EBZ A;  2JM5 A;  2OJ4 A;  3C7L A;  3PVU A;  3UZT A;  5HE3 A;  2IHB B;  4TNB A;  5HE1 A;  1OMW A;  1FQI A;  3NYO A;  3C7K B;  1AGR E;  2BCJ A;  5REQ B;  1EZT A;  4HTE A;  3KRW A;  3PSC A;  1FQK B; 
#chains in the Genus database with same CATH homology
 2JNU A;  3NYN A;  2AF0 A;  4TND A;  2V4Z B;  2BT2 A;  2IHD A;  2CRP A;  2IK8 B;  1DK8 A;  3CIK A;  2OWI A;  5DO9 B;  2BV1 A;  4PNK A;  1EMU A;  2D9J A;  2ODE B;  2GTP C;  3V5W A;  4EKD B;  3KRX A;  3PVW A;  5HE2 A;  1CMZ A;  1EZY A;  5HE0 A;  3QYF A;  4MK0 A;  1FQJ B;  2DLV A;  2EBZ A;  2JM5 A;  2OJ4 A;  3C7L A;  3PVU A;  3UZT A;  5HE3 A;  2IHB B;  4TNB A;  5HE1 A;  1OMW A;  1FQI A;  3NYO A;  3C7K B;  1AGR E;  2BCJ A;  5REQ B;  1EZT A;  3KRW A;  3PSC A;  1FQK B; 
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similar chains in the Genus database (?% sequence similarity)
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