2E7EA

Bent-binding of cyanide to the heme iron in rat heme oxygenase-1
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
212
structure length
212
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Alternative cyanide-binding modes to the haem iron in haem oxygenase
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 88
structure length 212
sequence length 212
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2007-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 2e7eA00
1XJZA 1S8CA 1XK1A 2DY5A 2QCXA 1OZEA 2A6BA 1OZRA 4G7PA 3CZYA 3RM5A 4G7UA 4G8PA 1OYLA 1WNWA 1N45A 4GPCA 1DVGA 4FN6A 3B5OA 3OQLA 1TWRA 1DVEA 3I8RA 3HOKA 1RCWA 1WOXA 3MVUA 1J02A 1XK2A 1TO9A 1UBBA 2RGZA 1TO9B 1IVJA 4WMHA 1IW0A 2QPPA 3B5PA 1WE1A 1XK0A 1J77A 2A2OA 3MOOA 1TYHA 4GPHA 1WNVA 1OZLA 2GM7A 3HLXA 4RAJA 3I9UA 4G7LA 3IBXA 3BJDA 1WZFA 1S13A 1TWNA 1IX4A 1WZDA 1WOWA 1YAFA 1IW1A 4G99A 4G8UA 1P3TA 5BTQA 3HNHA 2E7EA 1OTWA 4G98A 1OTVA 4NY7A 1ULXA 1WWMA 3NO6A 1Z72A 1IX3A 1NI6A 1P3UA 1UDDA 4WWJA 2RD3A 3TGMA 2A2MA 2F2GA 4G8WA 4WX0A 1V8XA 1J2CA 2GM8A 2QZCA 2Q32A 1WOVA 2Q4XA 3I9TA 4G7TA 1IRMA 3DDEA 1WNXA 4GPFA 1VGIA 1WZGA 4WD4A 2Z68A 1OZWA 1SK7A 3K4FA 1OYKA 1T5PA 2ZVUA 4LQXA 1P3VA 4GOHA 1XK3A 1YAKA 3HMLA 1RTWA 1N3UA 4WWZA 4MECA
chains in the Genus database with same CATH superfamily
1XJZA 1S8CA 1XK1A 2DY5A 2QCXA 1OZEA 2A6BA 1OZRA 4G7PA 3CZYA 3RM5A 4G7UA 4G8PA 1OYLA 1WNWA 1N45A 4GPCA 1DVGA 4FN6A 3B5OA 3OQLA 1TWRA 1DVEA 3I8RA 3HOKA 1RCWA 1WOXA 3MVUA 1J02A 1XK2A 1TO9A 1UBBA 2RGZA 1TO9B 1IVJA 4WMHA 1IW0A 2QPPA 3B5PA 1WE1A 1XK0A 1J77A 2A2OA 3MOOA 1TYHA 4GPHA 1WNVA 1OZLA 2GM7A 3HLXA 4RAJA 3I9UA 4G7LA 3IBXA 3BJDA 1WZFA 1S13A 1TWNA 1IX4A 1WZDA 1WOWA 1YAFA 1IW1A 4G99A 4G8UA 1P3TA 5BTQA 3HNHA 2E7EA 1OTWA 4G98A 1OTVA 4NY7A 1ULXA 1WWMA 3NO6A 1Z72A 1IX3A 1NI6A 1P3UA 1UDDA 4WWJA 2RD3A 3TGMA 2A2MA 2F2GA 4G8WA 4WX0A 1V8XA 1J2CA 2GM8A 2QZCA 2Q32A 1WOVA 2Q4XA 3I9TA 4G7TA 1IRMA 3DDEA 1WNXA 4GPFA 1VGIA 2LCUA 1WZGA 4WD4A 2Z68A 1OZWA 1SK7A 3K4FA 1OYKA 1T5PA 2ZVUA 4LQXA 1P3VA 4GOHA 1XK3A 1YAKA 3HMLA 1RTWA 1N3UA 4WWZA 4MECA
chains in the Genus database with same CATH topology
1XJZA 1S8CA 1XK1A 2DY5A 2QCXA 1OZEA 2A6BA 1OZRA 4G7PA 3CZYA 3RM5A 4G7UA 4G8PA 1OYLA 1WNWA 1N45A 4GPCA 1DVGA 4FN6A 3B5OA 3OQLA 1TWRA 1DVEA 3I8RA 3HOKA 1RCWA 1WOXA 3MVUA 1J02A 1XK2A 1TO9A 1UBBA 2RGZA 1TO9B 1IVJA 4WMHA 1IW0A 2QPPA 3B5PA 1WE1A 1XK0A 1J77A 2A2OA 3MOOA 1TYHA 4GPHA 1WNVA 1OZLA 2GM7A 3HLXA 4RAJA 3I9UA 4G7LA 3IBXA 3BJDA 1WZFA 1S13A 1TWNA 1IX4A 1WZDA 1WOWA 1YAFA 1IW1A 4G99A 4G8UA 1P3TA 5BTQA 3HNHA 2E7EA 1OTWA 4G98A 1OTVA 4NY7A 1ULXA 1WWMA 3NO6A 1Z72A 1IX3A 1NI6A 1P3UA 1UDDA 4WWJA 2RD3A 3TGMA 2A2MA 2F2GA 4G8WA 4WX0A 1V8XA 1J2CA 2GM8A 2QZCA 2Q32A 1WOVA 2Q4XA 3I9TA 4G7TA 1IRMA 3DDEA 1WNXA 4GPFA 1VGIA 1WZGA 4WD4A 2Z68A 1OZWA 1SK7A 3K4FA 1OYKA 1T5PA 2ZVUA 4LQXA 1P3VA 4GOHA 1XK3A 1YAKA 3HMLA 1RTWA 1N3UA 4WWZA 4MECA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XJZ A;  1S8C A;  1XK1 A;  2DY5 A;  2QCX A;  1OZE A;  2A6B A;  1OZR A;  4G7P A;  3CZY A;  3RM5 A;  4G7U A;  4G8P A;  1OYL A;  1WNW A;  1N45 A;  4GPC A;  1DVG A;  4FN6 A;  3B5O A;  3OQL A;  1TWR A;  1DVE A;  3I8R A;  3HOK A;  1RCW A;  1WOX A;  3MVU A;  1J02 A;  1XK2 A;  1TO9 A;  1UBB A;  2RGZ A;  1TO9 B;  1IVJ A;  4WMH A;  1IW0 A;  2QPP A;  3B5P A;  1WE1 A;  1XK0 A;  1J77 A;  2A2O A;  3MOO A;  1TYH A;  4GPH A;  1WNV A;  1OZL A;  2GM7 A;  3HLX A;  4RAJ A;  3I9U A;  4G7L A;  3IBX A;  3BJD A;  1WZF A;  1S13 A;  1TWN A;  1IX4 A;  1WZD A;  1WOW A;  1YAF A;  1IW1 A;  4G99 A;  4G8U A;  1P3T A;  5BTQ A;  3HNH A;  2E7E A;  1OTW A;  4G98 A;  1OTV A;  4NY7 A;  1ULX A;  1WWM A;  3NO6 A;  1Z72 A;  1IX3 A;  1NI6 A;  1P3U A;  1UDD A;  4WWJ A;  2RD3 A;  3TGM A;  2A2M A;  2F2G A;  4G8W A;  4WX0 A;  1V8X A;  1J2C A;  2GM8 A;  2QZC A;  2Q32 A;  1WOV A;  2Q4X A;  3I9T A;  4G7T A;  1IRM A;  3DDE A;  1WNX A;  4GPF A;  1VGI A;  1WZG A;  4WD4 A;  2Z68 A;  1OZW A;  1SK7 A;  3K4F A;  1OYK A;  1T5P A;  2ZVU A;  4LQX A;  1P3V A;  4GOH A;  1XK3 A;  1YAK A;  3HML A;  1RTW A;  1N3U A;  4WWZ A;  4MEC A; 
#chains in the Genus database with same CATH topology
 1XJZ A;  1S8C A;  1XK1 A;  2DY5 A;  2QCX A;  1OZE A;  2A6B A;  1OZR A;  4G7P A;  3CZY A;  3RM5 A;  4G7U A;  4G8P A;  1OYL A;  1WNW A;  1N45 A;  4GPC A;  1DVG A;  4FN6 A;  3B5O A;  3OQL A;  1TWR A;  1DVE A;  3I8R A;  3HOK A;  1RCW A;  1WOX A;  3MVU A;  1J02 A;  1XK2 A;  1TO9 A;  1UBB A;  2RGZ A;  1TO9 B;  1IVJ A;  4WMH A;  1IW0 A;  2QPP A;  3B5P A;  1WE1 A;  1XK0 A;  1J77 A;  2A2O A;  3MOO A;  1TYH A;  4GPH A;  1WNV A;  1OZL A;  2GM7 A;  3HLX A;  4RAJ A;  3I9U A;  4G7L A;  3IBX A;  3BJD A;  1WZF A;  1S13 A;  1TWN A;  1IX4 A;  1WZD A;  1WOW A;  1YAF A;  1IW1 A;  4G99 A;  4G8U A;  1P3T A;  5BTQ A;  3HNH A;  2E7E A;  1OTW A;  4G98 A;  1OTV A;  4NY7 A;  1ULX A;  1WWM A;  3NO6 A;  1Z72 A;  1IX3 A;  1NI6 A;  1P3U A;  1UDD A;  4WWJ A;  2RD3 A;  3TGM A;  2A2M A;  2F2G A;  4G8W A;  4WX0 A;  1V8X A;  1J2C A;  2GM8 A;  2QZC A;  2Q32 A;  1WOV A;  2Q4X A;  3I9T A;  4G7T A;  1IRM A;  3DDE A;  1WNX A;  4GPF A;  1VGI A;  2LCU A;  1WZG A;  4WD4 A;  2Z68 A;  1OZW A;  1SK7 A;  3K4F A;  1OYK A;  1T5P A;  2ZVU A;  4LQX A;  1P3V A;  4GOH A;  1XK3 A;  1YAK A;  3HML A;  1RTW A;  1N3U A;  4WWZ A;  4MEC A; 
#chains in the Genus database with same CATH homology
 1XJZ A;  1S8C A;  1XK1 A;  2DY5 A;  2QCX A;  1OZE A;  2A6B A;  1OZR A;  4G7P A;  3CZY A;  3RM5 A;  4G7U A;  4G8P A;  1OYL A;  1WNW A;  1N45 A;  4GPC A;  1DVG A;  4FN6 A;  3B5O A;  3OQL A;  1TWR A;  1DVE A;  3I8R A;  3HOK A;  1RCW A;  1WOX A;  3MVU A;  1J02 A;  1XK2 A;  1TO9 A;  1UBB A;  2RGZ A;  1TO9 B;  1IVJ A;  4WMH A;  1IW0 A;  2QPP A;  3B5P A;  1WE1 A;  1XK0 A;  1J77 A;  2A2O A;  3MOO A;  1TYH A;  4GPH A;  1WNV A;  1OZL A;  2GM7 A;  3HLX A;  4RAJ A;  3I9U A;  4G7L A;  3IBX A;  3BJD A;  1WZF A;  1S13 A;  1TWN A;  1IX4 A;  1WZD A;  1WOW A;  1YAF A;  1IW1 A;  4G99 A;  4G8U A;  1P3T A;  5BTQ A;  3HNH A;  2E7E A;  1OTW A;  4G98 A;  1OTV A;  4NY7 A;  1ULX A;  1WWM A;  3NO6 A;  1Z72 A;  1IX3 A;  1NI6 A;  1P3U A;  1UDD A;  4WWJ A;  2RD3 A;  3TGM A;  2A2M A;  2F2G A;  4G8W A;  4WX0 A;  1V8X A;  1J2C A;  2GM8 A;  2QZC A;  2Q32 A;  1WOV A;  2Q4X A;  3I9T A;  4G7T A;  1IRM A;  3DDE A;  1WNX A;  4GPF A;  1VGI A;  1WZG A;  4WD4 A;  2Z68 A;  1OZW A;  1SK7 A;  3K4F A;  1OYK A;  1T5P A;  2ZVU A;  4LQX A;  1P3V A;  4GOH A;  1XK3 A;  1YAK A;  3HML A;  1RTW A;  1N3U A;  4WWZ A;  4MEC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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