2EBZA

Solution structure of the rgs domain from human regulator of g-protein signaling 12 (rgs12)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
155
structure length
155
Chain Sequence
GSSGSSGRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the RGS domain from human Regulator of G-protein signaling 12 (RGS12)
rcsb
molecule keywords Regulator of G-protein signaling 12
molecule tags Signaling protein
source organism Homo sapiens
total genus 33
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2007-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ebzA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ebzA01
3CIKA 4PNKA 1FQIA 2BV1A 3NYNA 5HE1A 1EZYA 5HE3A 1EMUA 2ODEB 3KRWA 2BT2A 3V5WA 1AGRE 2GTPC 1FQKB 2AF0A 5HE0A 2IK8B 1CMZA 4MK0A 2JM5A 3KRXA 2JNUA 3C7KB 1FQJB 2EBZA 3PSCA 4EKDB 4TNDA 2OJ4A 2IHBB 4TNBA 1DK8A 5HE2A 2V4ZB 2BCJA 3PVWA 3NYOA 1OMWA 1EZTA 2D9JA 5DO9B 2IHDA 3UZTA 3PVUA 2CRPA 2OWIA 2DLVA 3C7LA
chains in the Genus database with same CATH superfamily
3CIKA 3I5QA 1FQIA 4PNKA 4HTEA 2BV1A 3NYNA 5HE1A 1EZYA 5HE3A 1EMUA 2ODEB 3KRWA 2BT2A 3V5WA 1AGRE 2GTPC 1FQKB 2AF0A 5HE0A 3QYFA 2IK8B 1CMZA 4MK0A 2JM5A 3KRXA 2JNUA 3C7KB 1FQJB 2EBZA 3PSCA 4EKDB 5REQB 4TNDA 2OJ4A 2IHBB 4TNBA 1DK8A 5HE2A 2V4ZB 2BCJA 3PVWA 3NYOA 1OMWA 1EZTA 2D9JA 5DO9B 2IHDA 3UZTA 3PVUA 2CRPA 2OWIA 2DLVA 3C7LA
chains in the Genus database with same CATH topology
3CIKA 4PNKA 1FQIA 2BV1A 3NYNA 5HE1A 1EZYA 5HE3A 1EMUA 2ODEB 3KRWA 2BT2A 3V5WA 1AGRE 2GTPC 1FQKB 2AF0A 5HE0A 3QYFA 2IK8B 1CMZA 4MK0A 2JM5A 3KRXA 2JNUA 3C7KB 1FQJB 2EBZA 3PSCA 4EKDB 5REQB 4TNDA 2OJ4A 2IHBB 4TNBA 1DK8A 5HE2A 2V4ZB 2BCJA 3PVWA 3NYOA 1OMWA 1EZTA 2D9JA 5DO9B 2IHDA 3UZTA 3PVUA 2CRPA 2OWIA 2DLVA 3C7LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CIK A;  4PNK A;  1FQI A;  2BV1 A;  3NYN A;  5HE1 A;  1EZY A;  5HE3 A;  1EMU A;  2ODE B;  3KRW A;  2BT2 A;  3V5W A;  1AGR E;  2GTP C;  1FQK B;  2AF0 A;  5HE0 A;  2IK8 B;  1CMZ A;  4MK0 A;  2JM5 A;  3KRX A;  2JNU A;  3C7K B;  1FQJ B;  2EBZ A;  3PSC A;  4EKD B;  4TND A;  2OJ4 A;  2IHB B;  4TNB A;  1DK8 A;  5HE2 A;  2V4Z B;  2BCJ A;  3PVW A;  3NYO A;  1OMW A;  1EZT A;  2D9J A;  5DO9 B;  2IHD A;  3UZT A;  3PVU A;  2CRP A;  2OWI A;  2DLV A;  3C7L A; 
#chains in the Genus database with same CATH topology
 3CIK A;  3I5Q A;  1FQI A;  4PNK A;  4HTE A;  2BV1 A;  3NYN A;  5HE1 A;  1EZY A;  5HE3 A;  1EMU A;  2ODE B;  3KRW A;  2BT2 A;  3V5W A;  1AGR E;  2GTP C;  1FQK B;  2AF0 A;  5HE0 A;  3QYF A;  2IK8 B;  1CMZ A;  4MK0 A;  2JM5 A;  3KRX A;  2JNU A;  3C7K B;  1FQJ B;  2EBZ A;  3PSC A;  4EKD B;  5REQ B;  4TND A;  2OJ4 A;  2IHB B;  4TNB A;  1DK8 A;  5HE2 A;  2V4Z B;  2BCJ A;  3PVW A;  3NYO A;  1OMW A;  1EZT A;  2D9J A;  5DO9 B;  2IHD A;  3UZT A;  3PVU A;  2CRP A;  2OWI A;  2DLV A;  3C7L A; 
#chains in the Genus database with same CATH homology
 3CIK A;  4PNK A;  1FQI A;  2BV1 A;  3NYN A;  5HE1 A;  1EZY A;  5HE3 A;  1EMU A;  2ODE B;  3KRW A;  2BT2 A;  3V5W A;  1AGR E;  2GTP C;  1FQK B;  2AF0 A;  5HE0 A;  3QYF A;  2IK8 B;  1CMZ A;  4MK0 A;  2JM5 A;  3KRX A;  2JNU A;  3C7K B;  1FQJ B;  2EBZ A;  3PSC A;  4EKD B;  5REQ B;  4TND A;  2OJ4 A;  2IHB B;  4TNB A;  1DK8 A;  5HE2 A;  2V4Z B;  2BCJ A;  3PVW A;  3NYO A;  1OMW A;  1EZT A;  2D9J A;  5DO9 B;  2IHD A;  3UZT A;  3PVU A;  2CRP A;  2OWI A;  2DLV A;  3C7L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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