2FU5A

Structure of rab8 in complex with mss4
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
117
structure length
107
Chain Sequence
QGHMVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleotide exchange via local protein unfolding-structure of Rab8 in complex with MSS4
pubmed doi rcsb
molecule keywords Guanine nucleotide exchange factor MSS4
molecule tags Signaling protein
source organism Homo sapiens
total genus 23
structure length 107
sequence length 117
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04421 Mss4 Mss4 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.10 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2fu5A00
1TXJA 1YZ1A 1H6QA 3P3KA 3EBMA 2FU5A 1HXRA 2LOYA 1FWQA 2HR9A 1H7YA 2KWBA
chains in the Genus database with same CATH superfamily
3ZD6A 2KV1A 5F98A 3HCJA 4CI3B 3GA3A 5F9FA 1HXRA 2LOYA 4BPBA 4TZ4C 2HR9A 4CI2B 2KWBA 1TXJA 3OG8A 2YKGA 2RQAA 3WX1A 2K8DA 2QFBA 3CEZA 3E0MA 3NCUA 4AY2A 4A2VA 2FU5A 3LRNA 3HCIA 4V30A 2RMJA 3HCHA 2RQBA 4TZCA 1H6QA 4A2XA 2KZNA 1L1DA 3LRRA 3EQTA 4CI1B 4V2YA 5E3HA 3EBMA 4V31A 3MAOA 1H7YA 3ZD7A 1YZ1A 5F9HA 3E0OA 3HCGA 3WX2A 5AMHA 3DJMA 3CXKA 3FACA 4TZUA 4V2ZA 2W4RA 1FWQA 2LVLA 3P3KA 2QFDA
chains in the Genus database with same CATH topology
3ZD6A 5F98A 3GA3A 5F9FA 1HXRA 2LOYA 4BPBA 2HR9A 2KWBA 1TXJA 3OG8A 2YKGA 2RQAA 2QFBA 4AY2A 3NCUA 4A2VA 2FU5A 3LRNA 2RMJA 4A2XA 2RQBA 1H6QA 3LRRA 3EQTA 5E3HA 3EBMA 1H7YA 3ZD7A 1YZ1A 5F9HA 3DJMA 3FACA 2W4RA 1FWQA 2LVLA 3P3KA 2QFDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TXJ A;  1YZ1 A;  1H6Q A;  3P3K A;  3EBM A;  2FU5 A;  1HXR A;  2LOY A;  1FWQ A;  2HR9 A;  1H7Y A;  2KWB A; 
#chains in the Genus database with same CATH topology
 3ZD6 A;  2KV1 A;  5F98 A;  3HCJ A;  4CI3 B;  3GA3 A;  5F9F A;  1HXR A;  2LOY A;  4BPB A;  4TZ4 C;  2HR9 A;  4CI2 B;  2KWB A;  1TXJ A;  3OG8 A;  2YKG A;  2RQA A;  3WX1 A;  2K8D A;  2QFB A;  3CEZ A;  3E0M A;  3NCU A;  4AY2 A;  4A2V A;  2FU5 A;  3LRN A;  3HCI A;  4V30 A;  2RMJ A;  3HCH A;  2RQB A;  4TZC A;  1H6Q A;  4A2X A;  2KZN A;  1L1D A;  3LRR A;  3EQT A;  4CI1 B;  4V2Y A;  5E3H A;  3EBM A;  4V31 A;  3MAO A;  1H7Y A;  3ZD7 A;  1YZ1 A;  5F9H A;  3E0O A;  3HCG A;  3WX2 A;  5AMH A;  3DJM A;  3CXK A;  3FAC A;  4TZU A;  4V2Z A;  2W4R A;  1FWQ A;  2LVL A;  3P3K A;  2QFD A; 
#chains in the Genus database with same CATH homology
 3ZD6 A;  5F98 A;  3GA3 A;  5F9F A;  1HXR A;  2LOY A;  4BPB A;  2HR9 A;  2KWB A;  1TXJ A;  3OG8 A;  2YKG A;  2RQA A;  2QFB A;  4AY2 A;  3NCU A;  4A2V A;  2FU5 A;  3LRN A;  2RMJ A;  4A2X A;  2RQB A;  1H6Q A;  3LRR A;  3EQT A;  5E3H A;  3EBM A;  1H7Y A;  3ZD7 A;  1YZ1 A;  5F9H A;  3DJM A;  3FAC A;  2W4R A;  1FWQ A;  2LVL A;  3P3K A;  2QFD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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