2IHBB

Crystal structure of the heterodimeric complex of human rgs10 and activated gi alpha 3
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
122
structure length
111
Chain Sequence
LKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(k) subunit alpha
molecule tags Signaling protein
source organism Homo sapiens
total genus 38
structure length 111
sequence length 122
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihbB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihbB01
2IK8B 1AGRE 3UZTA 2ODEB 1FQIA 1DK8A 5HE3A 2IHBB 3KRWA 1CMZA 2DLVA 3KRXA 5HE1A 3PVWA 3NYNA 2V4ZB 2BV1A 4TNBA 5DO9B 1OMWA 3V5WA 1FQJB 2JM5A 5HE0A 2OWIA 2BCJA 2GTPC 4EKDB 3C7LA 3PSCA 3CIKA 1EZTA 2IHDA 3PVUA 2D9JA 5HE2A 2AF0A 2BT2A 2OJ4A 4MK0A 2EBZA 1EMUA 3C7KB 4TNDA 3NYOA 1FQKB 4PNKA 2CRPA 2JNUA 1EZYA
chains in the Genus database with same CATH superfamily
2IK8B 1AGRE 3UZTA 3QYFA 2ODEB 1FQIA 1DK8A 5HE3A 5REQB 2IHBB 3KRWA 1CMZA 2DLVA 3KRXA 5HE1A 3PVWA 3NYNA 2V4ZB 2BV1A 4TNBA 5DO9B 1OMWA 3V5WA 1FQJB 2JM5A 5HE0A 2OWIA 2BCJA 2GTPC 4EKDB 3C7LA 3PSCA 3CIKA 3I5QA 1EZTA 2IHDA 3PVUA 2D9JA 5HE2A 2AF0A 2BT2A 2OJ4A 4MK0A 2EBZA 1EMUA 3C7KB 4TNDA 3NYOA 1FQKB 4PNKA 2CRPA 2JNUA 4HTEA 1EZYA
chains in the Genus database with same CATH topology
2IK8B 1AGRE 3UZTA 3QYFA 2ODEB 1FQIA 1DK8A 5HE3A 5REQB 2IHBB 3KRWA 1CMZA 2DLVA 3KRXA 5HE1A 3PVWA 3NYNA 2V4ZB 2BV1A 4TNBA 5DO9B 1OMWA 3V5WA 1FQJB 2JM5A 5HE0A 2OWIA 2BCJA 2GTPC 4EKDB 3C7LA 3PSCA 3CIKA 1EZTA 2IHDA 3PVUA 2D9JA 5HE2A 2AF0A 2BT2A 2OJ4A 4MK0A 2EBZA 1EMUA 3C7KB 4TNDA 3NYOA 1FQKB 4PNKA 2CRPA 2JNUA 1EZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IK8 B;  1AGR E;  3UZT A;  2ODE B;  1FQI A;  1DK8 A;  5HE3 A;  2IHB B;  3KRW A;  1CMZ A;  2DLV A;  3KRX A;  5HE1 A;  3PVW A;  3NYN A;  2V4Z B;  2BV1 A;  4TNB A;  5DO9 B;  1OMW A;  3V5W A;  1FQJ B;  2JM5 A;  5HE0 A;  2OWI A;  2BCJ A;  2GTP C;  4EKD B;  3C7L A;  3PSC A;  3CIK A;  1EZT A;  2IHD A;  3PVU A;  2D9J A;  5HE2 A;  2AF0 A;  2BT2 A;  2OJ4 A;  4MK0 A;  2EBZ A;  1EMU A;  3C7K B;  4TND A;  3NYO A;  1FQK B;  4PNK A;  2CRP A;  2JNU A;  1EZY A; 
#chains in the Genus database with same CATH topology
 2IK8 B;  1AGR E;  3UZT A;  3QYF A;  2ODE B;  1FQI A;  1DK8 A;  5HE3 A;  5REQ B;  2IHB B;  3KRW A;  1CMZ A;  2DLV A;  3KRX A;  5HE1 A;  3PVW A;  3NYN A;  2V4Z B;  2BV1 A;  4TNB A;  5DO9 B;  1OMW A;  3V5W A;  1FQJ B;  2JM5 A;  5HE0 A;  2OWI A;  2BCJ A;  2GTP C;  4EKD B;  3C7L A;  3PSC A;  3CIK A;  3I5Q A;  1EZT A;  2IHD A;  3PVU A;  2D9J A;  5HE2 A;  2AF0 A;  2BT2 A;  2OJ4 A;  4MK0 A;  2EBZ A;  1EMU A;  3C7K B;  4TND A;  3NYO A;  1FQK B;  4PNK A;  2CRP A;  2JNU A;  4HTE A;  1EZY A; 
#chains in the Genus database with same CATH homology
 2IK8 B;  1AGR E;  3UZT A;  3QYF A;  2ODE B;  1FQI A;  1DK8 A;  5HE3 A;  5REQ B;  2IHB B;  3KRW A;  1CMZ A;  2DLV A;  3KRX A;  5HE1 A;  3PVW A;  3NYN A;  2V4Z B;  2BV1 A;  4TNB A;  5DO9 B;  1OMW A;  3V5W A;  1FQJ B;  2JM5 A;  5HE0 A;  2OWI A;  2BCJ A;  2GTP C;  4EKD B;  3C7L A;  3PSC A;  3CIK A;  1EZT A;  2IHD A;  3PVU A;  2D9J A;  5HE2 A;  2AF0 A;  2BT2 A;  2OJ4 A;  4MK0 A;  2EBZ A;  1EMU A;  3C7K B;  4TND A;  3NYO A;  1FQK B;  4PNK A;  2CRP A;  2JNU A;  1EZY A; 
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similar chains in the pdb database (?% sequence similarity)

 
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