2IHDA

Crystal structure of human regulator of g-protein signaling 8, rgs8
Total Genus 51
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
127
structure length
127
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Regulator of G-protein signaling 8
molecule tags Signaling protein
source organism Homo sapiens
total genus 51
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihdA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihdA01
3UZTA 1CMZA 4TNDA 2DLVA 2JM5A 4MK0A 1EMUA 2AF0A 2OJ4A 4TNBA 1EZTA 2BV1A 3NYNA 1FQIA 2IHDA 1AGRE 2CRPA 2IK8B 3KRWA 1FQKB 3V5WA 3PVWA 1EZYA 3C7LA 2EBZA 2ODEB 3KRXA 3PVUA 1OMWA 2V4ZB 5DO9B 2BCJA 1FQJB 2BT2A 5HE2A 4EKDB 3PSCA 4PNKA 5HE0A 5HE1A 2IHBB 3C7KB 3NYOA 2D9JA 5HE3A 2GTPC 2OWIA 3CIKA 2JNUA 1DK8A
chains in the Genus database with same CATH superfamily
3UZTA 1CMZA 4TNDA 2DLVA 2JM5A 4MK0A 1EMUA 2AF0A 2OJ4A 4TNBA 1EZTA 2BV1A 3NYNA 1FQIA 2IHDA 1AGRE 2CRPA 2IK8B 3KRWA 5REQB 1FQKB 3V5WA 3PVWA 3QYFA 1EZYA 3C7LA 3I5QA 2EBZA 2ODEB 3KRXA 3PVUA 1OMWA 2V4ZB 5DO9B 2BCJA 1FQJB 2BT2A 5HE2A 4EKDB 3PSCA 4PNKA 5HE0A 5HE1A 2IHBB 3C7KB 3NYOA 2D9JA 5HE3A 2GTPC 2OWIA 3CIKA 2JNUA 1DK8A 4HTEA
chains in the Genus database with same CATH topology
3UZTA 1CMZA 4TNDA 2DLVA 2JM5A 4MK0A 1EMUA 2AF0A 2OJ4A 4TNBA 1EZTA 2BV1A 3NYNA 1FQIA 2IHDA 1AGRE 2CRPA 2IK8B 3KRWA 5REQB 1FQKB 3V5WA 3PVWA 3QYFA 1EZYA 3C7LA 2EBZA 2ODEB 3KRXA 3PVUA 1OMWA 2V4ZB 5DO9B 2BCJA 1FQJB 2BT2A 5HE2A 4EKDB 3PSCA 4PNKA 5HE0A 5HE1A 2IHBB 3C7KB 3NYOA 2D9JA 5HE3A 2GTPC 2OWIA 3CIKA 2JNUA 1DK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UZT A;  1CMZ A;  4TND A;  2DLV A;  2JM5 A;  4MK0 A;  1EMU A;  2AF0 A;  2OJ4 A;  4TNB A;  1EZT A;  2BV1 A;  3NYN A;  1FQI A;  2IHD A;  1AGR E;  2CRP A;  2IK8 B;  3KRW A;  1FQK B;  3V5W A;  3PVW A;  1EZY A;  3C7L A;  2EBZ A;  2ODE B;  3KRX A;  3PVU A;  1OMW A;  2V4Z B;  5DO9 B;  2BCJ A;  1FQJ B;  2BT2 A;  5HE2 A;  4EKD B;  3PSC A;  4PNK A;  5HE0 A;  5HE1 A;  2IHB B;  3C7K B;  3NYO A;  2D9J A;  5HE3 A;  2GTP C;  2OWI A;  3CIK A;  2JNU A;  1DK8 A; 
#chains in the Genus database with same CATH topology
 3UZT A;  1CMZ A;  4TND A;  2DLV A;  2JM5 A;  4MK0 A;  1EMU A;  2AF0 A;  2OJ4 A;  4TNB A;  1EZT A;  2BV1 A;  3NYN A;  1FQI A;  2IHD A;  1AGR E;  2CRP A;  2IK8 B;  3KRW A;  5REQ B;  1FQK B;  3V5W A;  3PVW A;  3QYF A;  1EZY A;  3C7L A;  3I5Q A;  2EBZ A;  2ODE B;  3KRX A;  3PVU A;  1OMW A;  2V4Z B;  5DO9 B;  2BCJ A;  1FQJ B;  2BT2 A;  5HE2 A;  4EKD B;  3PSC A;  4PNK A;  5HE0 A;  5HE1 A;  2IHB B;  3C7K B;  3NYO A;  2D9J A;  5HE3 A;  2GTP C;  2OWI A;  3CIK A;  2JNU A;  1DK8 A;  4HTE A; 
#chains in the Genus database with same CATH homology
 3UZT A;  1CMZ A;  4TND A;  2DLV A;  2JM5 A;  4MK0 A;  1EMU A;  2AF0 A;  2OJ4 A;  4TNB A;  1EZT A;  2BV1 A;  3NYN A;  1FQI A;  2IHD A;  1AGR E;  2CRP A;  2IK8 B;  3KRW A;  5REQ B;  1FQK B;  3V5W A;  3PVW A;  3QYF A;  1EZY A;  3C7L A;  2EBZ A;  2ODE B;  3KRX A;  3PVU A;  1OMW A;  2V4Z B;  5DO9 B;  2BCJ A;  1FQJ B;  2BT2 A;  5HE2 A;  4EKD B;  3PSC A;  4PNK A;  5HE0 A;  5HE1 A;  2IHB B;  3C7K B;  3NYO A;  2D9J A;  5HE3 A;  2GTP C;  2OWI A;  3CIK A;  2JNU A;  1DK8 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...