2IHDA

Crystal structure of human regulator of g-protein signaling 8, rgs8
Total Genus 51
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
127
structure length
127
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 8
total genus 51
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihdA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihdA01
3KRWA 3NYNA 2JM5A 3NYOA 5HE1A 2OWIA 2V4ZB 5HE2A 4MK0A 5HE3A 3C7KB 2ODEB 5DO9B 1OMWA 1AGRE 2AF0A 1CMZA 1FQKB 2JNUA 2GTPC 2OJ4A 2CRPA 2BT2A 2EBZA 4PNKA 4TNBA 2IHDA 3KRXA 1FQIA 4TNDA 3V5WA 1EZYA 2IHBB 3UZTA 2BCJA 2DLVA 1DK8A 1EMUA 3CIKA 3PVWA 2IK8B 2D9JA 3PSCA 1EZTA 5HE0A 2BV1A 3C7LA 4EKDB 1FQJB 3PVUA
chains in the Genus database with same CATH superfamily
3KRWA 3NYNA 2JM5A 3NYOA 5HE1A 2OWIA 2V4ZB 5HE2A 4MK0A 5HE3A 3C7KB 2ODEB 5DO9B 1OMWA 1AGRE 2AF0A 1CMZA 1FQKB 2JNUA 2GTPC 2OJ4A 2CRPA 2BT2A 2EBZA 4PNKA 4TNBA 2IHDA 3KRXA 1FQIA 4TNDA 3I5QA 3V5WA 1EZYA 2IHBB 3UZTA 2BCJA 2DLVA 3QYFA 1DK8A 1EMUA 3CIKA 5REQB 3PVWA 2IK8B 2D9JA 3PSCA 1EZTA 4HTEA 2BV1A 3C7LA 5HE0A 4EKDB 1FQJB 3PVUA
chains in the Genus database with same CATH topology
3KRWA 3NYNA 2JM5A 3NYOA 5HE1A 2OWIA 2V4ZB 5HE2A 4MK0A 5HE3A 3C7KB 2ODEB 5DO9B 1OMWA 1AGRE 2AF0A 1CMZA 1FQKB 2JNUA 2GTPC 2OJ4A 2CRPA 2BT2A 2EBZA 4PNKA 4TNBA 2IHDA 3KRXA 1FQIA 4TNDA 3V5WA 1EZYA 2IHBB 3UZTA 2BCJA 2DLVA 3QYFA 1DK8A 1EMUA 3CIKA 5REQB 3PVWA 2IK8B 2D9JA 3PSCA 1EZTA 5HE0A 2BV1A 3C7LA 4EKDB 1FQJB 3PVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRW A;  3NYN A;  2JM5 A;  3NYO A;  5HE1 A;  2OWI A;  2V4Z B;  5HE2 A;  4MK0 A;  5HE3 A;  3C7K B;  2ODE B;  5DO9 B;  1OMW A;  1AGR E;  2AF0 A;  1CMZ A;  1FQK B;  2JNU A;  2GTP C;  2OJ4 A;  2CRP A;  2BT2 A;  2EBZ A;  4PNK A;  4TNB A;  2IHD A;  3KRX A;  1FQI A;  4TND A;  3V5W A;  1EZY A;  2IHB B;  3UZT A;  2BCJ A;  2DLV A;  1DK8 A;  1EMU A;  3CIK A;  3PVW A;  2IK8 B;  2D9J A;  3PSC A;  1EZT A;  5HE0 A;  2BV1 A;  3C7L A;  4EKD B;  1FQJ B;  3PVU A; 
#chains in the Genus database with same CATH topology
 3KRW A;  3NYN A;  2JM5 A;  3NYO A;  5HE1 A;  2OWI A;  2V4Z B;  5HE2 A;  4MK0 A;  5HE3 A;  3C7K B;  2ODE B;  5DO9 B;  1OMW A;  1AGR E;  2AF0 A;  1CMZ A;  1FQK B;  2JNU A;  2GTP C;  2OJ4 A;  2CRP A;  2BT2 A;  2EBZ A;  4PNK A;  4TNB A;  2IHD A;  3KRX A;  1FQI A;  4TND A;  3I5Q A;  3V5W A;  1EZY A;  2IHB B;  3UZT A;  2BCJ A;  2DLV A;  3QYF A;  1DK8 A;  1EMU A;  3CIK A;  5REQ B;  3PVW A;  2IK8 B;  2D9J A;  3PSC A;  1EZT A;  4HTE A;  2BV1 A;  3C7L A;  5HE0 A;  4EKD B;  1FQJ B;  3PVU A; 
#chains in the Genus database with same CATH homology
 3KRW A;  3NYN A;  2JM5 A;  3NYO A;  5HE1 A;  2OWI A;  2V4Z B;  5HE2 A;  4MK0 A;  5HE3 A;  3C7K B;  2ODE B;  5DO9 B;  1OMW A;  1AGR E;  2AF0 A;  1CMZ A;  1FQK B;  2JNU A;  2GTP C;  2OJ4 A;  2CRP A;  2BT2 A;  2EBZ A;  4PNK A;  4TNB A;  2IHD A;  3KRX A;  1FQI A;  4TND A;  3V5W A;  1EZY A;  2IHB B;  3UZT A;  2BCJ A;  2DLV A;  3QYF A;  1DK8 A;  1EMU A;  3CIK A;  5REQ B;  3PVW A;  2IK8 B;  2D9J A;  3PSC A;  1EZT A;  5HE0 A;  2BV1 A;  3C7L A;  4EKD B;  1FQJ B;  3PVU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...