2IHDA

Crystal structure of human regulator of g-protein signaling 8, rgs8
Total Genus 51
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
127
structure length
127
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 8
total genus 51
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihdA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihdA01
4EKDB 1DK8A 2BT2A 5HE3A 5HE2A 3NYOA 5HE0A 1EMUA 2ODEB 2BV1A 3C7LA 2CRPA 5HE1A 4PNKA 4TNBA 1CMZA 2DLVA 1FQKB 2BCJA 2AF0A 3PVUA 5DO9B 3CIKA 3V5WA 1FQIA 2GTPC 3PVWA 2IK8B 4MK0A 3KRXA 3C7KB 1AGRE 2D9JA 3NYNA 4TNDA 2IHBB 3UZTA 2JM5A 2IHDA 1EZYA 2OJ4A 2JNUA 2EBZA 2OWIA 3PSCA 1OMWA 1EZTA 3KRWA 1FQJB 2V4ZB
chains in the Genus database with same CATH superfamily
4EKDB 1DK8A 2BT2A 5HE3A 5HE2A 3NYOA 5HE0A 1EMUA 2ODEB 2BV1A 3C7LA 2CRPA 5HE1A 4PNKA 4TNBA 1CMZA 3QYFA 2DLVA 5REQB 1FQKB 2BCJA 2AF0A 3PVUA 5DO9B 3CIKA 3V5WA 1FQIA 2GTPC 3PVWA 2IK8B 4HTEA 4MK0A 3KRXA 3C7KB 1AGRE 2D9JA 3NYNA 4TNDA 2IHBB 3UZTA 3I5QA 2JM5A 2IHDA 1EZYA 2OJ4A 2JNUA 2EBZA 2OWIA 3PSCA 1OMWA 1EZTA 3KRWA 1FQJB 2V4ZB
chains in the Genus database with same CATH topology
4EKDB 1DK8A 2BT2A 5HE3A 5HE2A 3NYOA 5HE0A 1EMUA 2ODEB 2BV1A 3C7LA 2CRPA 5HE1A 4PNKA 4TNBA 1CMZA 3QYFA 2DLVA 5REQB 1FQKB 2BCJA 2AF0A 3PVUA 5DO9B 3CIKA 3V5WA 1FQIA 2GTPC 3PVWA 2IK8B 4MK0A 3KRXA 3C7KB 1AGRE 2D9JA 3NYNA 4TNDA 2IHBB 3UZTA 2JM5A 2IHDA 1EZYA 2OJ4A 2JNUA 2EBZA 2OWIA 3PSCA 1OMWA 1EZTA 3KRWA 1FQJB 2V4ZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EKD B;  1DK8 A;  2BT2 A;  5HE3 A;  5HE2 A;  3NYO A;  5HE0 A;  1EMU A;  2ODE B;  2BV1 A;  3C7L A;  2CRP A;  5HE1 A;  4PNK A;  4TNB A;  1CMZ A;  2DLV A;  1FQK B;  2BCJ A;  2AF0 A;  3PVU A;  5DO9 B;  3CIK A;  3V5W A;  1FQI A;  2GTP C;  3PVW A;  2IK8 B;  4MK0 A;  3KRX A;  3C7K B;  1AGR E;  2D9J A;  3NYN A;  4TND A;  2IHB B;  3UZT A;  2JM5 A;  2IHD A;  1EZY A;  2OJ4 A;  2JNU A;  2EBZ A;  2OWI A;  3PSC A;  1OMW A;  1EZT A;  3KRW A;  1FQJ B;  2V4Z B; 
#chains in the Genus database with same CATH topology
 4EKD B;  1DK8 A;  2BT2 A;  5HE3 A;  5HE2 A;  3NYO A;  5HE0 A;  1EMU A;  2ODE B;  2BV1 A;  3C7L A;  2CRP A;  5HE1 A;  4PNK A;  4TNB A;  1CMZ A;  3QYF A;  2DLV A;  5REQ B;  1FQK B;  2BCJ A;  2AF0 A;  3PVU A;  5DO9 B;  3CIK A;  3V5W A;  1FQI A;  2GTP C;  3PVW A;  2IK8 B;  4HTE A;  4MK0 A;  3KRX A;  3C7K B;  1AGR E;  2D9J A;  3NYN A;  4TND A;  2IHB B;  3UZT A;  3I5Q A;  2JM5 A;  2IHD A;  1EZY A;  2OJ4 A;  2JNU A;  2EBZ A;  2OWI A;  3PSC A;  1OMW A;  1EZT A;  3KRW A;  1FQJ B;  2V4Z B; 
#chains in the Genus database with same CATH homology
 4EKD B;  1DK8 A;  2BT2 A;  5HE3 A;  5HE2 A;  3NYO A;  5HE0 A;  1EMU A;  2ODE B;  2BV1 A;  3C7L A;  2CRP A;  5HE1 A;  4PNK A;  4TNB A;  1CMZ A;  3QYF A;  2DLV A;  5REQ B;  1FQK B;  2BCJ A;  2AF0 A;  3PVU A;  5DO9 B;  3CIK A;  3V5W A;  1FQI A;  2GTP C;  3PVW A;  2IK8 B;  4MK0 A;  3KRX A;  3C7K B;  1AGR E;  2D9J A;  3NYN A;  4TND A;  2IHB B;  3UZT A;  2JM5 A;  2IHD A;  1EZY A;  2OJ4 A;  2JNU A;  2EBZ A;  2OWI A;  3PSC A;  1OMW A;  1EZT A;  3KRW A;  1FQJ B;  2V4Z B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...