2IHDA

Crystal structure of human regulator of g-protein signaling 8, rgs8
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
127
structure length
127
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Regulator of G-protein signaling 8
molecule tags Signaling protein
source organism Homo sapiens
total genus 51
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-09-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ihdA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ihdA01
2IHBB 2BT2A 3PVUA 2OJ4A 4EKDB 5DO9B 5HE2A 5HE0A 2BV1A 1EZTA 1EMUA 2D9JA 2JM5A 3PSCA 1DK8A 1FQIA 2V4ZB 1FQKB 3UZTA 3V5WA 4PNKA 4TNBA 2DLVA 3C7KB 2JNUA 3C7LA 3PVWA 1EZYA 3KRXA 1FQJB 4TNDA 2ODEB 5HE3A 4MK0A 1OMWA 1AGRE 3CIKA 2BCJA 5HE1A 2GTPC 2CRPA 2OWIA 3NYNA 2IK8B 3KRWA 2AF0A 3NYOA 2EBZA 2IHDA 1CMZA
chains in the Genus database with same CATH superfamily
2IHBB 2BT2A 3PVUA 2OJ4A 4EKDB 5DO9B 5HE2A 5HE0A 2BV1A 1EZTA 1EMUA 2D9JA 2JM5A 3PSCA 1DK8A 1FQIA 2V4ZB 3I5QA 5REQB 1FQKB 3UZTA 3V5WA 4PNKA 4TNBA 2DLVA 3C7KB 2JNUA 3C7LA 3PVWA 3QYFA 1EZYA 3KRXA 1FQJB 4TNDA 2ODEB 5HE3A 4MK0A 1OMWA 1AGRE 3CIKA 4HTEA 2BCJA 5HE1A 2GTPC 2CRPA 2OWIA 3NYNA 2IK8B 3KRWA 2AF0A 3NYOA 2EBZA 2IHDA 1CMZA
chains in the Genus database with same CATH topology
2IHBB 2BT2A 3PVUA 2OJ4A 4EKDB 5DO9B 5HE2A 5HE0A 2BV1A 1EZTA 1EMUA 2D9JA 2JM5A 3PSCA 1DK8A 1FQIA 2V4ZB 5REQB 1FQKB 3UZTA 3V5WA 4PNKA 4TNBA 2DLVA 3C7KB 2JNUA 3C7LA 3PVWA 3QYFA 1EZYA 3KRXA 1FQJB 4TNDA 2ODEB 5HE3A 4MK0A 1OMWA 1AGRE 3CIKA 2BCJA 5HE1A 2GTPC 2CRPA 2OWIA 3NYNA 2IK8B 3KRWA 2AF0A 3NYOA 2EBZA 2IHDA 1CMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IHB B;  2BT2 A;  3PVU A;  2OJ4 A;  4EKD B;  5DO9 B;  5HE2 A;  5HE0 A;  2BV1 A;  1EZT A;  1EMU A;  2D9J A;  2JM5 A;  3PSC A;  1DK8 A;  1FQI A;  2V4Z B;  1FQK B;  3UZT A;  3V5W A;  4PNK A;  4TNB A;  2DLV A;  3C7K B;  2JNU A;  3C7L A;  3PVW A;  1EZY A;  3KRX A;  1FQJ B;  4TND A;  2ODE B;  5HE3 A;  4MK0 A;  1OMW A;  1AGR E;  3CIK A;  2BCJ A;  5HE1 A;  2GTP C;  2CRP A;  2OWI A;  3NYN A;  2IK8 B;  3KRW A;  2AF0 A;  3NYO A;  2EBZ A;  2IHD A;  1CMZ A; 
#chains in the Genus database with same CATH topology
 2IHB B;  2BT2 A;  3PVU A;  2OJ4 A;  4EKD B;  5DO9 B;  5HE2 A;  5HE0 A;  2BV1 A;  1EZT A;  1EMU A;  2D9J A;  2JM5 A;  3PSC A;  1DK8 A;  1FQI A;  2V4Z B;  3I5Q A;  5REQ B;  1FQK B;  3UZT A;  3V5W A;  4PNK A;  4TNB A;  2DLV A;  3C7K B;  2JNU A;  3C7L A;  3PVW A;  3QYF A;  1EZY A;  3KRX A;  1FQJ B;  4TND A;  2ODE B;  5HE3 A;  4MK0 A;  1OMW A;  1AGR E;  3CIK A;  4HTE A;  2BCJ A;  5HE1 A;  2GTP C;  2CRP A;  2OWI A;  3NYN A;  2IK8 B;  3KRW A;  2AF0 A;  3NYO A;  2EBZ A;  2IHD A;  1CMZ A; 
#chains in the Genus database with same CATH homology
 2IHB B;  2BT2 A;  3PVU A;  2OJ4 A;  4EKD B;  5DO9 B;  5HE2 A;  5HE0 A;  2BV1 A;  1EZT A;  1EMU A;  2D9J A;  2JM5 A;  3PSC A;  1DK8 A;  1FQI A;  2V4Z B;  5REQ B;  1FQK B;  3UZT A;  3V5W A;  4PNK A;  4TNB A;  2DLV A;  3C7K B;  2JNU A;  3C7L A;  3PVW A;  3QYF A;  1EZY A;  3KRX A;  1FQJ B;  4TND A;  2ODE B;  5HE3 A;  4MK0 A;  1OMW A;  1AGR E;  3CIK A;  2BCJ A;  5HE1 A;  2GTP C;  2CRP A;  2OWI A;  3NYN A;  2IK8 B;  3KRW A;  2AF0 A;  3NYO A;  2EBZ A;  2IHD A;  1CMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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